Clinical trials: Thoracoscopy, active
Lung, Lung Adenocarcinoma
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs.
- Conditions
- Lung, Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Cancer, Non-Small Cell
- Trial name
- NCT06602661
- Testing
- Fissureless Lobectomy with Reinforced Staple Lines, Fissureless Lobectomy with Non-Reinforced Staple Lines
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Surrey Thoracic Surgery Group
Pleural Infection
Study of Medical Thoracoscopy in Early Pleural Infection
Pleural infection (which is the infection in the space around the lungs called the pleura) is a severe infection that is difficult to treat and can lead substantial disability or even death.
- Trial name
- STEP (NCT07858721)
- Testing
- Medical thoracoscopy plus standard of care, Standard of Care (Investigator Choice)
- Volunteers
- 128 people
- Sponsor
- Alexandria University
Pain, Postoperative, Intrathoracic Procedure
Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
The researchers will compare the common methods of post-surgical pain control, such as epidural or intercostal nerve block with a newer method called cryoablation.
- Trial name
- NCT06384664
- Testing
- Atricure's crysoSPHERE probe, Standard of Care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Malignant Pleural Effusion
Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion
Comparision between pleurodesis by pleural abrasion using medical thoracoscopy and bleomycin instillation via indwelling pleural catheter.
- Trial name
- NCT06691009
- Testing
- Group 1 (mechanical pleurodesis), Group 2 chemical pleurodesis by bleomycin)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Pleural Effusion Disorder
Dual-function Semirigid Thoracoscopy Versus Rigid Thoracoscopy for the Diagnosis of Pleural Disease
Medical thoracoscopy (rigid and semirigid) is an effective, safe method for diagnosing and managing pleural diseases. Rigid thoracoscopy demonstrates superior overall diagnostic yield compared to semirigid techniques (flexible…
- Trial name
- NCT07114783
- Testing
- Dual-function semi-rigid thoracoscopy, Rigid thoracoscopy
- Volunteers
- 92 people
- Sponsor
- China-Japan Friendship Hospital
Pleural Effusion Disorder
Ultrasounic Elastography-guided Pleural Biopsy Followed by As-needed Medical Thoracoscopic Pleural Biopsy Versus Immediate Medical Thoracoscopic Pleural Biopsy for the Diagnosis of Pleural Effusion
Brief Summary The goal of this clinical trial is to determine whether an initial diagnostic approach using ultrasound elastography-guided pleural biopsy (UEPB) is non-inferior to immediate medical thoracoscopic pleural biopsy in…
- Trial name
- NCT07419620
- Testing
- Ultrasoinc elastography-guided pleural biopsy followed by as-needed medical thoracoscopic pleural biopsy, Semi-rigid thoracoscopic pleural biopsy
- Where
- China
- Volunteers
- 420 people
- Sponsor
- China-Japan Friendship Hospital
Diabete Mellitus, VATS
Total Intravenous and Balanced Anesthesia in Diabetic Patients Undergoing Video-Assisted Thoracoscopy
Video-assisted thoracoscopy is a minimally invasive surgical technique used to diagnose and treat problems in chest. Diabetics are more prone to infections, slower wound healing and other complications during and after surgery.
- Conditions
- Diabete Mellitus, VATS, TIVA
- Trial name
- NCT07496593
- Testing
- Propofol + fentanyl + Atracurium, Isoflurane and Atracurium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Esketamine Plus Dexmedetomidine Affect Postoperative Quality, Thoracoscopy
The Effect of Esketamine Combined With Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thoracoscopic Surgery
Brief Summary：Video-assisted thoracoscopic surgery (VATS) has a wide range of applications, including the diagnosis and treatment of lung cancer, and has gradually replaced traditional open thoracotomy.
- Conditions
- Esketamine Plus Dexmedetomidine Affect Postoperative Quality, Thoracoscopy, Lung Neoplasms
- Trial name
- NCT07125573
- Testing
- Saline Solution (NaCl 0,9%), Low-dose esketamine infusion, High-dose esketamine infusion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Malignant Pleural Effusions (Mpe), Medical Thoracoscopy
Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural Effusion
Pleural effusion is a common problem in hospital patients. It may arise from a wide range of diseases. There is a multitude of recognised causes of pleural effusion, and in addition, other pleural conditions such as pleural…
- Conditions
- Malignant Pleural Effusions (Mpe), Medical Thoracoscopy, Pleural Effusion
- Trial name
- FLEXPLEUR2 (NCT07726784)
- Testing
- Single-Use Flexible Bronchoscope, Semi-Rigid Pleuroscope
- Where
- 2 sites in Malaysia
- Volunteers
- 36 people
- Sponsor
- National University of Malaysia
Air Leak From Lung, Lung Surgery
Prospective Study Evaluating the Effectiveness of Intraoperative Ventilation for Predicting Postoperative Air Leaks During Major Lung Resections by Conventional or Robotic Thoracoscopy
Air leak from lung after major pulmonary resections is alveolar-pleural microfistulas resulting from damage to the visceral pleura during lung surgery.
- Trial name
- NODRAIN (NCT07350265)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pleural Diseases
Dual-function Semirigid Thoracoscopy Versus Semirigid Thoracoscopy for the Diagnosis of Pleural Diseases: A Multicenter Open-label Randomized Controlled Trial
We designed and developed a novel dual-function semirigid thoracoscope (UE FET-680; UE Corporation, Zhejiang, China) with a straight channel adapted to flexible and rigid forceps for pleural biopsy.
- Trial name
- NCT06744725
- Testing
- Pleural biopsy using dual-function semirigid thoracoscopy, Pleural biopsy using semirigid thoracoscopy
- Where
- China
- Volunteers
- 334 people
- Sponsor
- China-Japan Friendship Hospital
Medical Thoracoscopy
Safety and Efficacy of Dexmedetomidate vs. Midazolam for Procedural Sedation During Medical Thoracoscopy
Medical thoracoscopy can be performed under procedural sedation (conscious sedation) in most of the cases. Procedural sedation is a state where the patient lies comfortably without much movement, does not feel pain and has a…
- Trial name
- DEMISE-MT (NCT07184801)
- Testing
- Dexmedetomidine, Midazolam
- Where
- India
- Volunteers
- 56 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pleural Infection, Pleural Infections
Role of Medical Thoracoscopy in Pleural Infection (PROMPT Trial)
The PROMPT study is testing whether an early keyhole procedure called Medical Thoracoscopy, which lets doctors look inside the chest and remove infected fluid, works better than current standard treatment (medicines to break up…
- Conditions
- Pleural Infection, Pleural Infections, Pleural Infections and Inflammations
- Trial name
- PROMPT (NCT07550530)
- Testing
- medical thoracoscopy, Standard of Care
- Volunteers
- 170 people
- Sponsor
- Università Politecnica delle Marche
Malignant Pleural Neoplasm
EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement
This phase II trial investigates the effect of EXPAREL compared to lidocane as a local anesthetic in patients who are undergoing pleuroscopy with pleural biopsy and indwelling pleural catheter placement.
- Trial name
- NCT05044468
- Testing
- Lidocaine, Liposomal Bupivacaine, Questionnaire Administration
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative, Pharmacokinetics
Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy
The purpose of this study is to assess pharmacokinetics of liposomal bupivacaine (Exparel) after multilevel intercostal injections of this local anesthetic for pain control during and after thoracoscopic surgeries.
- Trial name
- NCT03737292
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Esophageal Cancer
Clinical Study on the Efficacy of Single-port Inflatable Mediastinoscopy Combined With Laparoscopic-assisted Small Incision Surgery and Thoracoscopy Combined With Laparoscopic Surgery for Radical Esophagectomy
We previously developed a novel non-trans thoracic esophagectomy, the single-port inflatable mediastinoscopy combined with laparoscopy for the radical esophagectomy of esophageal cancer.This study is evaluating the feasibility…
- Trial name
- NCT05105945
- Testing
- Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery, Thoracoscopy Combined With Laparoscopic Surgery
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Mesotheliomas Pleural, Malignant Pleural Mesothelioma
The IMmunotherapy Pleural 5-ALA PDT
Pilot study of the feasibility of an innovative multimodal treatment combining intrapleural photodynamic therapy with videothoracoscopy followed by adjuvant immunotherapy with anti-PD-1 Nivolumab antibodies in patients with…
- Trial name
- IMPALA (NCT04400539)
- Testing
- intrapleural photodynamic therapy with videothoracoscopy, Nivolumab Injection
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Lille
Thymoma
Robot-assisted vs VATS for Thymoma
The aim of this study is to explore the advantages of robot-assisted thymectomy in long-term survival benefits and short-term clinical efficacy compared with video-assisted thoracoscopic thymectomy based on a multi-center…
- Trial name
- NCT06029621
- Testing
- RATS for Thymectomy, VATS for Thymectomy
- Where
- 2 sites in China
- Volunteers
- 304 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Suspected Malignant Lung Neoplasm, Pleural Effusion
First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.
Non randomized study with two groups. The study group includes patients with suspected malignant pleural effusion, in whom the investigation of pleural effusion begins directly with pleural biopsy by Local Anesthesia Thoracoscopy…
- Conditions
- Suspected Malignant Lung Neoplasm, Pleural Effusion, Pleural Effusion, Malignant, Mesothelioma, Malignant
- Trial name
- FLAT (NCT06946498)
- Testing
- Local Anesthesia Thoracoscopy, Pleuroscopy with Rigid Thoracoscope and Forceps biopsies
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
PLEURA DISEASE
Ultrasound Guided Erectror Spinae Block Versus Intracavitary During Medical Thoracoscopy
The primary aim: is to compare the effect of US guided ESP block at two levels versus intracavitary blockade in medical thoracoscopy on total peri-procedural (intraoperative and post-operative 12 hours) nalbuphine consumption…
- Trial name
- ESPB (NCT07572019)
- Testing
- ultrasound-guided erector spinae plane block in medical pleuroscopy, Intracavitary anaesthesia ICA
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University