Clinical trials: Thromboembolic Disease
Intracranial Thrombosis
Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates
Our overall aim is to examine if ultrasound is as accurate as MRI and/or CT in the evaluation of dural venous sinuses. We hypothesize that sonography will be accurate (accuracy >80%) for diagnosing specific anatomic findings of…
- Trial name
- NCT00555932
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- The Hospital for Sick Children
Venous Thromboembolism
Comparative Study of Prophylactic Agent for Venous Thromboembolism After Total Knee Arthroplasty
The purpose of this study is to compare the efficacy of two prophylactic agent(aspirin 300mg/day and rivaroxaban 10mg/day) for venous thromboembolism after total knee arthroplasty.
- Trial name
- NCT02271399
- Testing
- acetylsalicylic acid, rivaroxaban
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Hanyang University Seoul Hospital
Cardiovascular Diseases, Thromboembolism
Epidemiology of Venous Thromboembolism
To evaluate potentially modifiable lifestyle predictors of venous thromboembolism and their joint associations with biochemical and genetic determinants.
- Conditions
- Cardiovascular Diseases, Thromboembolism, Peripheral Vascular Diseases
- Trial name
- NCT00041457
- Sponsor
- Brigham and Women's Hospital
Extracorporeal Membrane Oxygenation Complication, Hemorrhage
ECMO Hemostatic Transfusions in Children
Critically ill children supported by extracorporeal membrane oxygenation (ECMO) receive large volumes of prophylactic platelet transfusions to prevent bleeding.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Thromboembolism, Transfusion Adverse Reaction
- Trial name
- ECSTATIC (NCT05796557)
- Testing
- Platelet Transfusion
- Where
- 10 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- Yale University
Malignant Tumor
Evaluation of Fibrin Structure Marker in Cancer Patients Treated and Not Treated With LMWH
The purpose of the study is to assess the fibrin structure marker in the plasma of cancer patients, treated or not treated with LMWH at prophylactic or therapeutic doses, in order to determine the venous thromboembolic risk.
- Trial name
- FICT (NCT02552381)
- Testing
- Fibrin Structure
- Where
- France
- Volunteers
- 389 people
- Sponsor
- Diagnostica Stago R&D
Cardiovascular Diseases, Thromboembolism
Risk Factors for Venous Thromboembolism in the Community
To evaluate the trends in the incidence of venous thromboembolism, to determine the risk factors for venous thromboembolism in patients with medical and surgical illness, and to evaluate the efficacy of the anticoagulant therapy…
- Trial name
- NCT00011180
- Where
- United States
- Volunteers
- 385 people
- Sponsor
- Mayo Clinic
Venous Thrombosis, Critical Illness
Risk Prediction of Venous Thromboembolism in Critically Ill
Introduction: Venous thromboembolism (VTE), including both deep vein thrombosis and pulmonary embolism, is a frequent cause of morbidity and mortality.
- Trial name
- NCT03773939
- Where
- Netherlands
- Volunteers
- 5,400 people
- Sponsor
- University Medical Center Groningen
Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Right Atrial Fibrosis in Pulmonary Hypertension
The study aim to assess right atrial (RA) remodeling, in terms of RA fibrosis, in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients.
- Conditions
- Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension
- Trial name
- RAFE-PH (NCT04663230)
- Testing
- cardiac magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Cerebral Venous Thrombosis
The Efficacy and Safety of Dabigatran Etexilate for the Treatment of Cerebral Venous Thrombosis
This is a single-center, prospective, randomized (1:1), open-label study with two parallel groups. This study is planned to investigate the efficacy and safety of dabigatran etexilate comparing with warfarin for the treatment of…
- Trial name
- NCT03217448
- Testing
- Dabigatran etexilate, Warfarin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Capital Medical University
Pulmonary Embolism, Venous Thromboembolism
Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use
The researchers hypothesize that existing-prescription notifications directed to pharmacists are more likely to lead to a prescription change than existing-prescription notifications directed to prescribers.
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Atrial Fibrillation
- Trial name
- NCT05351749
- Testing
- New-prescription Alert, New-prescription Alert with referral option, Existing-prescription notification to prescriber
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- University of Michigan
Venous Thromboembolism
Screening for Occult Malignancy in Idiopathic Venous Thromboembolism
Prospective controlled randomized study. Aim of this study is to assess the feasibility and sensitivity of CT scanning of the thorax, abdomen and pelvis for the detection of occult cancer in patients with idiopathic venous…
- Trial name
- NCT00361647
- Testing
- Diagnostic screening for occult malignancy
- Where
- Italy
- Sponsor
- University of Padova
Malignant Neoplasm
Radiation Impact on Thromboembolic Events
The aim of the present study is to determine the frequency and to identify main risk factors for venous thromboembolism of venous thromboembolic complications in a population of cancer patients treated with a curative intent by…
- Trial name
- RIT (NCT02696447)
- Testing
- Biomarkers assays
- Where
- 2 sites in France
- Volunteers
- 450 people
- Sponsor
- Institut de Cancérologie de la Loire
Thromboembolism
OASIS-6 : The Safety and Efficacy of Fondaparinux Versus Control Therapy in Patients With ST Segment Elevation Acute Myocardial Infarction
This is a randomized, double blindcontrolled, parallel group, multi-center, multinational study of fondaparinux vs. control in patients with STEMI (ST segment myocardial infarction) randomized within 24 hours of the onset of…
- Trial name
- NCT00064428
- Testing
- fondaparinux - UFH not indicated, Control - UFH not indicated, Fondaparinux - UFH indicated
- Volunteers
- 12,092 people
- Sponsor
- GlaxoSmithKline
Cerebral Thrombosis, Venous Thrombosis
TOF-MRV Versus Post-Contrast 3D T1 MRI in Dural Venous Sinus Thrombosis
This cross-sectional study aims to compare the diagnostic performance of time-of-flight MR venography and post-contrast 3D T1-weighted MRI in the detection of dural venous sinus thrombosis.
- Trial name
- NCT07888062
- Volunteers
- 80 people
- Sponsor
- Assiut University
Venous Thromboembolism
Detecting Circulating Emboli in Patients with Acute Venous Thromboembolism
The purpose of this study is to further evaluate and adjust the photoacoustic flow cytometry device and its use in detecting circulating emboli.
- Trial name
- PAFC (NCT02735759)
- Testing
- Photoacoustic flow cytometry device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arkansas
COVID, Acute Coronary Syndrome
Cardiovascular Complications and COVID-19 (CovCardioVasc-Study)
Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death).
- Conditions
- COVID, Acute Coronary Syndrome, Myocardial Infarction, Myocarditis
- Trial name
- CovCardioVasc (NCT04335162)
- Where
- 8 sites in France
- Volunteers
- 198 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Venous Thromboembolism
Active Comparator-Controlled Study to Assess Safety and Efficacy of ISIS-FXIRx in Total Knee Arthroplasty
The purpose of this study is: To assess the safety and efficacy profile of ISIS-FXIRx, including incidence of bleeding and VTE, in patients undergoing total knee arthroplasty.
- Trial name
- NCT01713361
- Testing
- ISIS-FXIRx Dose #2, ISIS-FXIRx Dose #3, Enoxaparin
- Where
- 21 sites in Bulgaria, Canada and 3 more
- Volunteers
- 315 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Pelvic Fractures, Acetabular Fractures
Incidence of Venous Thromboembolism in Patients With Pelvic and Acetabular Fractures (PAF)
The goal of this observational study is to investigate the incidence of venous thromboembolism (VTE) in patients with pelvic and acetabular fractures (PAF).
- Conditions
- Pelvic Fractures, Acetabular Fractures, Pelvic Trauma, Venous Thromboembolic Event
- Trial name
- PAF-VTE (NCT07165587)
- Testing
- Bilateral duplex ultrasonography
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Venous Thromboembolism, Malignancy
Mortality Due to Malignancy in Patients With Idiopathic Venous Thromboembolism
Background Patients with an idiopathic venous thromboembolism (IVTE) appear to have a risk of approximately 10% for symptomatic malignancy within 3 years after the IVTE.
- Trial name
- Trousseau (NCT01088334)
- Testing
- screening
- Where
- 10 sites in Netherlands
- Volunteers
- 630 people
- Sponsor
- Slotervaart Hospital
Thromboembolism
Thromboprophylaxis and Bariatric Surgery
This trial is an assessment of the efficacy of three thromboprophylaxis regimens in two types of bariatric surgery. gastric banding and gastric bypass on anti-Xa activity levels The study includes two groups of 150 patients…
- Trial name
- NCT00444652
- Testing
- Enoxaparin
- Where
- 10 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France