Clinical trials: Thrombosis, Venous
Venous Thromboembolism (VTE), Post Partum Women
Prevention of Postpartum Venous Thromboembolism in Women at Intermediate Risk
Venous thromboembolism (VTE) is currently the second cause of death in women of reproductive age worldwide. The incidence of VTE during pregnancy is 1.2 to 1.4/1000 women, half of VTE occurring during postpartum and as PE in…
- Trial name
- MUM-VTE (NCT06845423)
- Testing
- Low molecular weight heparin
- Where
- 18 sites in France
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Brest
Sleep Apnea Syndromes, Venous Thromboembolism
Sleep Apnea and Tromboembolic Disease
There is some evidence for a hypercoagulable state in sleep apnea-hipopnea syndrome (SAHS), which could play a role in the increased cardiovascular morbility and mortality.
- Trial name
- NCT00501358
- Where
- Spain
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Venous Thrombosis
Evaluation of PD 0348292 for Preventing Blood Clots in the Lungs or Deep Leg Veins of Patients After Knee Surgery
To study the safety and effectiveness of several doses of PD 0348292 compared to enoxaparin in preventing blood clots in the lungs or deep leg veins of patients after knee surgery
- Trial name
- NCT00306254
- Testing
- PD 0348292, Enoxaparin
- Where
- 134 sites in United States, Australia and 14 more
- Volunteers
- 1,225 people
- Sponsor
- Pfizer
Decompressive Craniectomy, Brain Injuries
Good Prognosis Factors After Decompressive Craniectomy : a Ten-year Retrospective Study
Decompressive craniectomy is a treatment of refractory intracranial hypertension after various etiologies : malignant ischemic stroke, traumatic brain injury, intraparenchymal hemorrhage, aneurysmal subarachnoid hemorrhage…
- Conditions
- Decompressive Craniectomy, Brain Injuries, Treatment Outcome
- Trial name
- NCT04682951
- Testing
- Decompressive Craniectomy
- Where
- France
- Volunteers
- 544 people
- Sponsor
- Central Hospital, Nancy, France
Age-related Macular Degeneration, Diabetic Macular Edema
Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGF
Comparable data for bevacizumab and aflibercept are lacking, as are studies comparing the systemic levels of ranibizumab, bevacizumab, and aflibercept and their relative effects on circulating vascular endothelial growth factor.
- Conditions
- Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
- Trial name
- NCT02118831
- Testing
- Blood Sample Collection, Aflibercept, Bevacizumab
- Volunteers
- 56 people
- Sponsor
- California Retina Consultants
Venous Thromboembolic Disease
Cost Effectiveness Analysis of an Ancillary Study of the REMOTEV Study
The implications of the medico-economic impact are essential in the choice of first-line therapists. The economic impact is an important criterion to recommend the privileged use of Direct Oral Anticoagulants (AOD) in first…
- Trial name
- NCT03887806
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Venous Thromboembolism (VTE), Occult Cancer
External Validation of the CLOVER Score for Detecting Occult Cancer in Venous Thromboembolism Patients
This study aims to externally validate the CLOVER score, a machine learning-based predictive model designed to identify patients with venous thromboembolism (VTE) who are at increased risk of having an occult cancer.
- Trial name
- CLOVER (NCT07310693)
- Where
- 12 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Infanta Leonor University Hospital
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Venous Thrombosis
Venous Thromboembolism Taskforce Audit Program
To determine the effect of an interventional campaign run by a dedicated "VTE Nurse Educator" over a 6-month period and the effect on prophylaxis rates.
- Trial name
- NCT00535171
- Where
- Australia
- Volunteers
- 8,764 people
- Sponsor
- Sanofi
Liver Cirrhosis
Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis
The aim of this study is to investigate the pharmacokinetic and pharmacodynamic parameters of rivaroxaban and apixaban in patients with compensated liver cirrhosis (Child-Pugh class A and B).
- Trial name
- NCT04874428
- Testing
- Rivaroxaban 10 mg Oral Tablet, Apixaban 2.5 mg Oral Tablet
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Primary Brain Tumor
Innohep for Prophylaxis of Venous Thromboembolism in Brain Tumor Patients
To determine the safety of prophylaxis with Tinzaparin low molecular weight heparin in primary brain tumor patients. 2. To determine the incidence of deep venous thrombosis or pulmonary embolism in brain tumor patients who will…
- Trial name
- NCT00629447
- Testing
- Innohep
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Pulmonary Embolism, Embolism
Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
The clinical significance of pulmonary embolism (PE) limited to the subsegmental pulmonary arteries, so called isolated subsegmental pulmonary embolism (SSPE), remains controversial.
- Conditions
- Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases
- Trial name
- SAFE-SSPE (NCT04263038)
- Testing
- Rivaroxaban
- Where
- 40 sites in Belgium, Canada and 3 more
- Volunteers
- 276 people
- Sponsor
- Drahomir Aujesky
Deep Vein Thrombosis
Prophylactic Anticoagulation for Preventing Deep Vein Thrombosis After Total Hip Arthroplasty
Deep vein thrombosis (DVT) remains a life-threatening complication of arthroplasty. It remains controversial for anticoagulation strategies after total hip arthroplasty (THA).
- Trial name
- NCT01446887
- Testing
- prophylactic anticoagulation
- Where
- China
- Sponsor
- JIANG Qing
Fractures
Prediction of Venous Thrombosis After Fracture Operation: Comparative Analysis of Different Fracture Sites
The goal of this observational study is to analyze the clinical characteristics of patients who develop lower limb deep vein thrombosis (DVT) following fracture surgery, with a focus on comparing different fracture sites.
- Trial name
- NCT06877052
- Where
- China
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Foshan Hospital of Traditional Chinese Medicine
Deep Vein Thrombosis
Ultrasound (US)-Doppler for the Diagnosis of Asymptomatic Deep Vein Thrombosis (DVT) in Gynecologic Cancer Patients
The aim of this study is to determine the prevalence of asymptomatic lower extremity DVT detected by Doppler ultrasound in a selected group of patients suffering from gynecological malignancies.
- Trial name
- NCT00285038
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical…
- Conditions
- Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Branch Retinal Vein Occlusion
- Trial name
- VOYAGER (NCT05476926)
- Testing
- Faricimab, Port Delivery System with Ranibizumab
- Where
- 299 sites in United States, Argentina and 27 more
- Volunteers
- 6,000 people
- Sponsor
- Hoffmann-La Roche
Contraception, Female Contraception
Postmarketing Study of ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) in Relation to Venous Thromboembolism (Blood Clots), Stroke and Heart Attacks
The purpose of the study is to assess the occurrence of venous thromboembolism (blood clots), stroke, and heart attack in current users of ORTHO EVRA compared to current users of norgestimate-containing oral contraceptives with…
- Trial name
- NCT00331071
- Testing
- Monophasic or triphasic Oral contraceptive tablet, Ortho Evra transdermal patch containing 6 mg NGMN/0.75 mg EE
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Deep Vein Thrombosis
Ancillary Study of the ULTREC Project
The ULTREC research project is designed to assess the safety of a negative strategy relying on Colour Doppler Ultrasound (CDUS) for excluding the diagnosis of a new thrombosis.
- Trial name
- ULTRECAncillar (NCT05300139)
- Testing
- Color Doppler Ultrasound
- Where
- 12 sites in France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Central Venous Catheter Thrombosis
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical…
- Trial name
- PHOTO CAT (NCT06417541)
- Testing
- Diseased patients with an indwelling central venous catheter who is referred to autopsy, Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Thomas Kander
Macular Edema, Retinal Vein Occlusion
Study of Ozurdex® Treatment Practice in Patients With Macular Oedema Due to Retinal Vein Occlusion
Epidemiological study of Ozurdex® in sites treating patients with retinal vein occlusion.
- Trial name
- NCT01618266
- Testing
- dexamethasone intravitreal implant
- Where
- France
- Volunteers
- 375 people
- Sponsor
- Allergan
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