Clinical trials: Thumb Carpometacarpal Osteoarthritis
Rhizarthrosis
Rhizarthrosis Study
Rhizarthrosis is the wear of the thumb saddle joint. It is a very common disease affecting up to 25% of postmenopausal women. There are currently various conservative and surgical methods available for treatment.
- Trial name
- RHI (NCT04587570)
- Testing
- Infiltration with PRP, Infiltration with Fat, Infiltration with PRP and Fat
- Where
- Austria
- Volunteers
- 131 people
- Sponsor
- Medical University of Graz
Thumb Osteoarthritis, Hand Osteoarthritis
Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis
One of the standard treatment methods in individuals with thumb osteoarthritis (OA) is exercise. Combination therapy options involving these exercises can be applied to patients.
- Trial name
- NCT07112742
- Testing
- High-Intensity Laser Therapy and Exercise, High-Intensity Laser Therapy at a Non-Therapeutic Dose Combined With Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- TC Erciyes University
Thumb Carpometacarpal Joint Osteoarthritis
Biomechanical Evaluation With Finite Element Models in Thumb Carpometacarpal Osteoarthitis: Prospective Comparative Analysis of Loads in Arthroplasty With or Without Implants
To better understand the load distribution in the Thumb Carpometacarpal Joint (CMC joint) in presence of osteoarthritis and how surgery by means of a suspension-resection arthroplasty or a joint replacement by means of a metal…
- Trial name
- NCT07614269
- Testing
- Trapezectomy and carpometacarpal joint resection-supension arthroplasty, Trapeziometacarpal joint prosthesis
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Thumb Osteoarthritis
Trapeziometacarpal Joint Arthroplasty Versus Trapeziectomy for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is common and may cause severe pain and functional limitation. Trapeziectomy is widely used, whereas prosthetic arthroplasty may offer faster early recovery.
- Trial name
- T3 (NCT07552831)
- Testing
- trapeziometacarpal arthroplasty, Trapeziectomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Thumb Carpometacarpal Joint Osteoarthritis
Platelet-rich Plasma for Thumb Carpometacarpal Joint Osteoarthritis
The purpose of this study is to investigate a case series of patients treated with Platelet-rich plasma for thumb carpometacarpal joint osteoarthritis.
- Trial name
- NCT04886349
- Testing
- Platelet-rich plasma
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic
Thumb Osteoarthritis
Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis
Compare outcomes of ARA for isolated CMC OA versus to simultaneous ARA of CMC plus STT
- Trial name
- ARA:BJA-OA (NCT02958137)
- Testing
- Arthroscopic Resection Arthroplasty
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Specialist, PC, Davenport, IA
Thumb Osteoarthritis
Can Video Assisted Therapy Replace In-Person Occupational Therapy After Hand Surgery: a Noninferiority Study
This study will investigate a video assisted, home therapy program where participants complete hand therapy on their own following thumb arthroplasty. In this program, participants will receive prerecorded informational videos.
- Trial name
- NCT04625244
- Testing
- Video assisted home therapy
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Osteoarthritis Thumb, Joint Diseases
Radial Nerve Mobilization in Hand Thumb Osteoarthritis Patients
Hand-thumb carpometacarpal (1st CMC) joint osteoarthritis is defined as the degeneration occurring between the articular surfaces of the 1st metacarpal bone and the trapezium bone.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Radial Neuropathy
- Trial name
- NCT05650970
- Testing
- routine therapy, radial nerve mobilization exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Gazi University
Osteoarthritis Thumb Base Joint
Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial
This clinical trial aims to evaluate the safety and effectiveness of the lnDx Implant in the treatment of thumb base joint arthritis.
- Trial name
- THANKS (NCT05644132)
- Testing
- InDx Implant for the carpometacarpal joint
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Loci Orthopaedics
Carpometacarpal Osteoarthritis
Thumb Osteoarthritis: A Cross-Sectional Study of Mechanisms
This study examines carpometacarpal osteoarthritis (CMC OA) and aims to elucidate the biomechanical, neuromuscular, and somatosensory mechanisms that contribute to CMC OA symptoms by using orthopaedic biomechanics and…
- Trial name
- NCT04104477
- Testing
- Range of Motion Tasks, Strength Tasks
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Florida
Thumb Osteoarthritis
Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty
This study aims to compare post-surgical outcomes of individuals who receive either a custom orthosis or prefabricated splint after carpometacarpal arthroplasty.
- Trial name
- NCT05307510
- Testing
- Prefabricated splint, Custom Orthosis
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Toledo
Osteoarthritis Thumb, Thumb Carpometacarpal Joint Osteoarthritis
TOUCH® CMC 1 New Enrollment US Study
The purpose of this study is to meet a PMA (P240020) condition of approval of the TOUCH® CMC 1 Prosthesis to evaluate the effectiveness and safety of the prosthesis in the United States (US) population.
- Trial name
- PAS002 (NCT07405983)
- Testing
- TOUCH® CMC 1 Prosthesis
- Where
- 4 sites in United States
- Volunteers
- 163 people
- Sponsor
- Keri Medical SA
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
GraftJacket Versus Tendon Interposition for Trapeziometacarpal Osteoarthritis
Studies at the shoulder, Achilles tendon and thumb show satisfactory results regarding the use of GaftJacket. Initial trials at the thumb show, that the GraftJacket can be safely and successfully used in TMC OA surgery and…
- Trial name
- NCT01724840
- Testing
- GraftJacket, Tendon Interposition
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Schulthess Klinik
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Osteoarthritis Thumb, Osteoarthritis, Knee
Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints
The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints.
- Conditions
- Osteoarthritis Thumb, Osteoarthritis, Knee, Metabolic Disease
- Trial name
- NCT06370312
- Testing
- Trapeziectomy
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Trapeziometacarpal Osteoarthritis, Thumb Carpometacarpal Osteoarthritis
Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 2-3
Trapeziometacarpal osteoarthritis is a common cause of pain and loss of hand function in postmenopausal women. Many surgical treatments have been described and recent literature has show that the relatively simple trapeziectomy…
- Trial name
- NCT02204488
- Testing
- Total Joint Arthroplasty, Trapeziectomy
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Isala
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Use of FlexHD as Post Trapeziectomy Spacer
The objective of this study is to show that using FlexHD® (or HADM) to fill the empty space created by removal of the trapezium improves the subject's outcome and subsequent functionality of the basilar joint arthroplasty…
- Trial name
- MTF (NCT01998594)
- Testing
- Arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Rhizarthrosis
Dual Mobility Total Joint Prosthesis (Touch) for Thumb Carpometacarpal Joint Osteoarthritis
The dual mobility concept currently represents the newest generation of thumb carpometacarpal prostheses. The aim of this study was to evaluate the outcomes of TOUCH® prosthesis.
- Trial name
- NCT05047744
- Testing
- Touch Dual Mobility CMC I Prosthesis
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Kepler University Hospital
Thumb Osteoarthritis
Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision-Making
This is a retrospective cohort study utilizing radiographic and computed tomography (CT) imaging data collected during routine clinical care at Schulthess Klinik Zürich.
- Trial name
- TMCAI (NCT07148349)
- Testing
- No Intervention: Observational Cohort
- Where
- Switzerland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Thumb Osteoarthritis, Hand Injuries
Extracorporeal Shock Waves Therapy (ESWT) vs Exercise in Thumb Osteoarthritis
Osteoarthritis (OA) is a chronic joint disease with a high prevalence and a negative impact on the quality of life and a high economic burden.
- Trial name
- SWEX-TO (NCT06056765)
- Testing
- "Minilith", Storz, Swiss
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari