Clinical trials: Thumb Carpometacarpal Osteoarthritis, active
Carpometacarpal (CMC) Osteoarthritis
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
The goal of this study is to investigate if a timed release steroid injection may be beneficial in treating carpometacarpal (CMC) joint (thumb) osteoarthritis. The main questions to be answered are: 1.
- Trial name
- NCT06237153
- Testing
- Triamcinolone Acetonide extended release suspension
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marie Badalamente
Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis
The goal of this clinical trial is to learn about the use of turmeric (Curcumin) as a treatment for pain of thumb-joint arthritis. Turmeric is commonly being used as an over-the-counter treatment for musculoskeletal pain.
- Trial name
- NCT06359665
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brent DeGeorge
Trapeziometacarpal Osteoarthritis, Thumb Osteoarthritis
ICF-Based Biopsychosocial Assessment With AI-Assisted Profile Prediction: Trapeziometacarpal Osteoarthritis Model
Trapeziometacarpal osteoarthritis (TMC OA) is a common condition affecting the base of the thumb that causes pain, weakness, and difficulty with daily hand use.
- Conditions
- Trapeziometacarpal Osteoarthritis, Thumb Osteoarthritis, Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
- Trial name
- ICF (NCT07458971)
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Hacettepe University
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
Rhizarthrosis
Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb
Only 4 randomized controlled clinical trials have been published to date to assess the short-term effectiveness of intra-articular Botulinum Toxin injection on pain, function and quality of life in patients suffering from chronic…
- Trial name
- NCT04829565
- Testing
- Botulinum toxin
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Trapeziometacarpal Osteoarthritis
Thumb Proprioception in Trapeziometacarpal Osteoarthritis
This study looks at people who have osteoarthritis at the base of the thumb. It examines how well the thumb can sense its position and movement. The study has three goals: 1.
- Trial name
- NCT07447323
- Testing
- Thumb Proprioception Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Thumb Osteoarthritis
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the…
- Trial name
- NCT04828954
- Testing
- Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Thumb Osteoarthritis, Hand Osteoarthritis
Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis
One of the standard treatment methods in individuals with thumb osteoarthritis (OA) is exercise. Combination therapy options involving these exercises can be applied to patients.
- Trial name
- NCT07112742
- Testing
- High-Intensity Laser Therapy and Exercise, High-Intensity Laser Therapy at a Non-Therapeutic Dose Combined With Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- TC Erciyes University
Thumb Carpometacarpal Joint Osteoarthritis
Biomechanical Evaluation With Finite Element Models in Thumb Carpometacarpal Osteoarthitis: Prospective Comparative Analysis of Loads in Arthroplasty With or Without Implants
To better understand the load distribution in the Thumb Carpometacarpal Joint (CMC joint) in presence of osteoarthritis and how surgery by means of a suspension-resection arthroplasty or a joint replacement by means of a metal…
- Trial name
- NCT07614269
- Testing
- Trapezectomy and carpometacarpal joint resection-supension arthroplasty, Trapeziometacarpal joint prosthesis
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Thumb Osteoarthritis
Trapeziometacarpal Joint Arthroplasty Versus Trapeziectomy for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is common and may cause severe pain and functional limitation. Trapeziectomy is widely used, whereas prosthetic arthroplasty may offer faster early recovery.
- Trial name
- T3 (NCT07552831)
- Testing
- trapeziometacarpal arthroplasty, Trapeziectomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis Thumb, Thumb Carpometacarpal Joint Osteoarthritis
TOUCH® CMC 1 New Enrollment US Study
The purpose of this study is to meet a PMA (P240020) condition of approval of the TOUCH® CMC 1 Prosthesis to evaluate the effectiveness and safety of the prosthesis in the United States (US) population.
- Trial name
- PAS002 (NCT07405983)
- Testing
- TOUCH® CMC 1 Prosthesis
- Where
- 4 sites in United States
- Volunteers
- 163 people
- Sponsor
- Keri Medical SA
Osteoarthritis Thumb, Osteoarthritis, Knee
Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints
The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints.
- Conditions
- Osteoarthritis Thumb, Osteoarthritis, Knee, Metabolic Disease
- Trial name
- NCT06370312
- Testing
- Trapeziectomy
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Thumb Osteoarthritis
Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision-Making
This is a retrospective cohort study utilizing radiographic and computed tomography (CT) imaging data collected during routine clinical care at Schulthess Klinik Zürich.
- Trial name
- TMCAI (NCT07148349)
- Testing
- No Intervention: Observational Cohort
- Where
- Switzerland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Thumb Osteoarthritis
Thumb Base Osteoarthritis: Ultrasound-guided Platelet-rich Plasma Versus Placebo Injection
The goal of this clinical trial is to evaluate whether platelet-rich plasma (PRP) injections improve pain and function in adults with thumb base osteoarthritis (CMC-I OA).
- Trial name
- Thumbs-up (NCT07491302)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Saline (0.9% NaCl)
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- Goed Medisch Centrum