Clinical trials: Thumb Osteoarthritis
Osteoarthritis Thumb
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
- Trial name
- NCT06193499
- Testing
- Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Thumb Arthritis
The Impact of Thumb Carpometacarpal Osteoarthritis on General Health
This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of…
- Trial name
- NCT01133197
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis Thumb
Restoration of Thumb Strength and Function in Basal Joint Arthritis: A Comparative Effectiveness Trial (RESTART)
The purpose of this study is to evaluate the basis for three widely held fundamental tenets about surgical intervention for thumb basal joint arthritis; 1.
- Trial name
- RESTART (NCT04458584)
- Testing
- Trapeziectomy with ligament reconstruction (I; LRTI), Trapeziectomy with suture suspensionplasty (II; SS), Arthroscopic Trapeziectomy (III; AT)
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Thumb Osteoarthritis
Distraction vs Interposition Arthroplasty for Basilar Thumb Osteoarthritis
Surgical management for osteoarthritis of the thumb is indicated when conservative measures have failed, and numerous techniques have been proposed.
- Trial name
- NCT04155853
- Testing
- Interposition Arthroplasty, Hematoma and Distraction Arthroplasty
- Where
- Greece
- Volunteers
- 22 people
- Sponsor
- Aristotle University Of Thessaloniki
Carpometacarpal (CMC) Osteoarthritis
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
The goal of this study is to investigate if a timed release steroid injection may be beneficial in treating carpometacarpal (CMC) joint (thumb) osteoarthritis. The main questions to be answered are: 1.
- Trial name
- NCT06237153
- Testing
- Triamcinolone Acetonide extended release suspension
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marie Badalamente
Thumb Osteoarthritis
Thumb Carpometacarpal Joint Denervation Versus Trapeziectomy
This is a prospective study tracking the outcomes of patients who undergo either of two treatments for thumb carpo-metacarpal joint arthritis: trapeziectomy with ligament reconstruction (LRTI) or denervation.
- Trial name
- NCT03558204
- Testing
- Denervation of the thumb CMC joint, trapeziectomy with ligament reconstruction (LRTI)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Johns Hopkins University
Osteoarthritis Thumb, Arthrosis of First Carpometacarpal Joint
CMC I Stability Intraoperative
The goal of the current study is to objectively measure intraoperative the initial thumb stability after trapezium removal when performing trapeziectomy, alone or in combination with suspension and tendon interposition and to…
- Conditions
- Osteoarthritis Thumb, Arthrosis of First Carpometacarpal Joint, Joint Instability
- Trial name
- NCT03687775
- Testing
- Stability assessment
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Schulthess Klinik
Osteoarthritis, Osteoarthritis Thumb Base Joint
Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis
The goal of this study is to determine the success rate of a single Carpometacarpal (CMC) thumb injection after arthroplasty surgery for primary osteoarthritis of the CMC joint.
- Conditions
- Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
- Trial name
- CTM CMC (NCT06171529)
- Testing
- CTM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana Hand to Shoulder Center
Thumb Osteoarthritis
Efficacy of Trapeziectomy Versus Sham Surgery in the Treatment of Osteoarthritis at the Base of the Thumb
A multi-center randomized placebo-controlled clinical trial which determines the efficacy of trapeziectomy in patients with persistent painful osteoarthritis at the base of the thumb.
- Trial name
- FINTASY (NCT05127005)
- Testing
- Trapeziectomy
- Where
- 4 sites in Finland
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Osteoarthritis Thumb Base Joint
Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial
This clinical trial aims to evaluate the safety and effectiveness of the lnDx Implant in the treatment of thumb base joint arthritis.
- Trial name
- THANKS (NCT05644132)
- Testing
- InDx Implant for the carpometacarpal joint
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Loci Orthopaedics
Osteoarthritis
Safety Study of Thumb Orthoses in Osteoarthritis in the Base of the Thumb (BTOA)
The prevalence of digital osteoarthritis varies according to whether a radiological or clinical definition is adopted. Interventions: Thumb orthoses to be worn at night and usual care vs usual care.
- Trial name
- NCT00350896
- Testing
- Thumb orthoses
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Soft Tissue Injuries, Distal Radius Fracture
Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.
Trauma and soft injuries of the wrist, hand and fingers have a high incidence, and large social and healthcare costs are generated, mainly due to productivity loss.
- Conditions
- Soft Tissue Injuries, Distal Radius Fracture, Metacarpal Fracture, Carpal Fracture
- Trial name
- NCT04669704
- Testing
- Experimental: Tablet application, Comparator: Conventional treatment
- Where
- 2 sites in Spain
- Volunteers
- 663 people
- Sponsor
- University of Seville
Osteoarthritis Thumb
Influence of the Radiological Stage on the Efficiency of Viscosupplementation in Basal Thumb Arthritis
The rhizarthrose is the most frequent affection of the hand at the age fifty and beyond. For the moderate forms of the disease, the majority of the studies recommend the recourse to the viscosupplement because of its efficiency…
- Trial name
- INSTINCT (NCT03622736)
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Labrha
Osteoarthritis
Thumb Muscle Thickness and Strength in CMC Osteoarthritis
A total of 34 patients aged between 50-80 years, diagnosed with first carpometacarpal joint osteoarthritis based on hand radiographs taken within the last 3 months, will be included in the study from the Physical Therapy and…
- Trial name
- NCT06730698
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Beylikduzu State Hospital
Rhizarthrosis
Study of Medical Ultrasound for Rhizarthrosis
It was never investigated which preservative non-invasive treatments are superior to treat rhizarthrosis. This randomized study compares the effect of 1. hand therapy vs. 2. therapeutic ultrasound vs. 3.
- Trial name
- NCT04115085
- Testing
- Hand therapy (18 treatments), Therapeutic ultrasound (18 treatments), Combined hand therapy and therapeutic ultrasound (18 treatments)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Waldfriede Hospital
Osteoarthritis, Hip, Osteoarthritis Thumb
Evaluate Clinical Benefit of Local Treatment With KD Intra-Articular® Gel in Patients With Osteoarthritis (NO-DOLOR2)
Prospective observational, national, multicentre, open study with a class III medical device with EC marking. Study to evaluate the clinical benefit of local treatment with KD intra-articular® gel in patients with osteoarthritis…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis Thumb, Osteoarthritis Ankle
- Trial name
- NO-DOLOR2 (NCT05275244)
- Testing
- KD Intra-Articular® gel
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Procare Health Iberia S.L.
Thumb Osteoarthritis
Effectiveness of Proprioceptive Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Objective: To establish the effectiveness of a proprioceptive training program as a complementary therapy for a traditional protocol in position control, pain intensity, upper limb function and occupation performance for patients…
- Trial name
- NCT04777526
- Testing
- Proprioception exercises, Joint protection program, Thumb orthosis
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- University of Malaga
Hand Osteoarthritis, Wrist Osteoarthritis
Effects of 12-week Digital Treatment in Patients With Hand OA on Pain and Function
The purpose of this study is to evaluate the effect of a 12 week digital treatment program for patients with hand osteoarthritis.
- Conditions
- Hand Osteoarthritis, Wrist Osteoarthritis, Thumb Osteoarthritis, Finger Osteoarthritis
- Trial name
- NCT05499559
- Testing
- Joint Academy digital treatment
- Where
- Sweden
- Volunteers
- 846 people
- Sponsor
- Joint Academy
Hand Osteoarthritis
Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis
The aim of this study is to compare the effect of Whale and Colditz static orthosis on pain and functional abilities of hand in thumb carpometacarpal osteoarthritis as a unique treatment.
- Trial name
- NCT02780999
- Testing
- Whale orthosis, Colditz orthosis
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Malaga