Clinical trials: Thyroid; Functional Disturbance
Thyroid Dysfunction
Thyroid Dysfunction in Head and Neck Surgery Patients
Specific Aim I: Determine absorption of iodine after oropharyngeal application of povidone-iodine 10% solution when used in head and neck surgery involving the upper aero-digestive tract.
- Trial name
- NCT00592514
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Arkansas
Thyroid Diseases, Hypocalcemia
Use of Prophylactic Steroids in the Prevention of Post-thyroidectomy Hypocalcaemia and Voice Dysfunction
Total thyroidectomy for benign surgical pathologies is associated with risks related to temporary hypocalcaemia and vocal quality dysfunction.
- Conditions
- Thyroid Diseases, Hypocalcemia, Vocal Cord Dysfunction
- Trial name
- NCT04752852
- Testing
- Dexamethasone
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Pakistan
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Diabete Mellitus, Hypogonadism
Hypothalamic-pituitary Dysfunction in Diabetes
Type 2 Diabetes mellitus (T2DM) is a chronic disease with a high prevalence and several comorbidities impacting on public health and society.
- Conditions
- Diabete Mellitus, Hypogonadism, Hypogonadotropic Hypogonadism, Hypergonadotropic Hypogonadism
- Trial name
- DIAPO (NCT05752591)
- Testing
- Diagnostic testing
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Auxologico Italiano
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia
Infants and children undergoing cardiac surgery require mechanical support for circulation called cardiopulmonary bypass. The artificial pump ensures that blood flow to the body is maintained during surgical procedure on the…
- Trial name
- I-TRICC (NCT02222532)
- Testing
- Tetronine
- Where
- Indonesia
- Volunteers
- 224 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Coronary Atherosclerosis, Coronary Artery Disease
Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging
In a prospective international multicenter observational study, 1080 stable chest pain patients (REALITY Advanced registry of CCTA patients) with the suspected chronic coronary syndrome will be enrolled.
- Conditions
- Coronary Atherosclerosis, Coronary Artery Disease, Contrast-induced Nephropathy, Cerebrovascular Disease
- Trial name
- REALITY (NCT02440646)
- Testing
- Coronary computed tomography angiography, Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 4 sites in Estonia, Netherlands and 1 more
- Volunteers
- 1,080 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Chronic Kidney Disease on Hemodialysis, Thyroid Gland Disease
Interleukin-6 and Thyroid Dysfunction in Hemodialysis Patients
Chronic kidney disease (CKD) is often associated with multiorgan complications, including thyroid hormone dysfunction. Interleukin-6 (IL-6), a pro-inflammatory cytokine, has been proposed as a marker of inflammation that may…
- Trial name
- NCT07328113
- Testing
- Thyroid hormone
- Where
- Indonesia
- Volunteers
- 65 people
- Sponsor
- Dr. Soetomo General Hospital
Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect
Thyroid Dysfunction and Nivolumab Reponse in NSCLC
This is an observational, retrospective and monocentric study, conducted at the university Hospital of Brest The primary objective is to assess the association between the occurrence of thyroid dysfunction in patients treated…
- Conditions
- Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect, Thyroid Dysfunction, Immune Checkpoint Inhibitor
- Trial name
- THYRONIVO (NCT04470440)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Brest
Major Depressive Disorder, Metabolic Syndrome
Incidence of Metabolic Syndrome and Thyroid Dysfunction in Patients With Major Depressive Disorder
Aim 1 is to study prevalence and 1 year incidence of metabolic syndrome in major depressive disorder and factors correlation. Aim 2 is to study prevalence and 1 year incidence of thyroid dysfunction in major depressive disorder…
- Conditions
- Major Depressive Disorder, Metabolic Syndrome, Thyroid Dysfunction
- Trial name
- NCT01682785
- Volunteers
- 140 people
- Sponsor
- Chiang Mai University
Thyroid Dysfunction, Acute Illness
Thyroid Profiles in Patients With Acute Illness
Patients admitted to the hospital with acute illness may have a wide spectrum of thyroid function abnormalities. It is largely unknown whether such aberrations are temporary or persist for a long time, and whether they impact…
- Trial name
- NCT05980923
- Testing
- Performing blood thyroid test (TSH, FT4, FT3)
- Where
- Jordan
- Sponsor
- Jordan Collaborating Cardiology Group
Thyroid Dysfunction
Serum Thyroid Function After Iodinated Contrast Administration
This study investigated the changes in serum thyroid function and urinary iodine levels before and after the use of iodinated contrast to analyze the prevalence of thyroid dysfunction in the Chinese euthyroid adults after using…
- Trial name
- NCT05786846
- Testing
- Iodinated contrast agents
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Dysfunction, Atherosclerosis
The TRUST Study - CardioVascular Imaging IMT
Coronary heart disease (CHD) are the leading causes of mortality and morbidity, particularly with the current context of an aging population.
- Conditions
- Thyroid Dysfunction, Atherosclerosis, Heart Failure
- Trial name
- NCT02832934
- Testing
- Levothyroxine
- Where
- 3 sites in Switzerland
- Volunteers
- 184 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Kidney Disease, Thyroid Dysfunction
Evaluation of Thyroid Function in Patients With Chronic Kidney Disease
A higher prevalence of thyroid disease has been associated with chronic kidney disease (CKD), and subclinical hypothyroidism seems to be the most common dysfunction.
- Trial name
- NCT04658524
- Testing
- Thyroid function
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Rio de Janeiro State University
Hypopituitarism, Hypogonadism
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant Recipients
This study will determine the prevalence of endocrine-related side effects in children who have been treated for cancer and establish a database and registry organized according to cancer diagnosis, treatments and endocrine side…
- Conditions
- Hypopituitarism, Hypogonadism, Thyroid Dysfunction, Bone Diseases, Metabolic
- Trial name
- NCT00504218
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Dietary Iodine Deficiency, Thyroid; Functional Disturbance
Serum Thyroglobulin as a Marker of Iodine Status During Pregnancy
The purpose of the investigation is to assess iodine status of pregnant women at week 16 of gestation targeting serum thyroglobulin as a biomarker of iodine deficiency.
- Trial name
- NCT02927119
- Testing
- iodine
- Volunteers
- 189 people
- Sponsor
- University of Debrecen
Thyroid Dysfunction
Thyroid Dysfunction in Patients With Nephrotic Syndrome
This study is to evaluate Thyroid Hormone profile in patients with Nephrotic syndrome to identify clinical predictor of Thyroid dysfunction in patients with Nephrotic syndrome
- Trial name
- NCT04323007
- Testing
- Nephrotic patients
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Merna Makram
Keratoconus in Thyroid Gland Dysfunction
Prevalence Of Keratoconus Among Patients With Thyroid Gland Dysfunction
Hormonal imbalances are likely to affect the corneal metabolism and may be also associated with Keratoconus. Among the various endocrinologic dysfunctions assumed so far, thyroid gland dysfunction (TGD) (hypo- or hyperthyroidism…
- Trial name
- NCT04346992
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Fayoum University
Abortion, Spontaneous, Pregnancy Complications
Relation Between Subclinical Hypothyroidism and Outcome of Pregnancy
Studies have demonstrated a relationship between subclinical hypothyroidism and obstetrics complications like preterm delivery, pre-eclampsia, placental abruption and stillbirth.
- Conditions
- Abortion, Spontaneous, Pregnancy Complications, Subclinical Hypothyroidism
- Trial name
- GravThyr (NCT01335802)
- Where
- Denmark
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Low Birth Weight Neonates
Hospital-Based Phthalate Exposure in Very Low Birth Weight Neonates
In this observational pilot project, the investigators plan to document duration and sources of exposure to plasticizers in infants born at birth weights less than 1500 grams.
- Trial name
- NCT01420029
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypocalcemia, Thyroid
Is Correcting Total Serum Calcium Levels Important After Thyroidectomy
This study is designed as a prospective non-randomized longitudinal single- center cohort study to evaluate the importance of correcting total serum calcium levels.
- Conditions
- Hypocalcemia, Thyroid, Parathyroid Dysfunction, Calcium Disorder
- Trial name
- NCT04304573
- Testing
- Total serum calcium blood test
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Sestre Milosrdnice