Clinical trials: Thyroid Cancers
Fine Needle Aspiration Cytology, Thyroid Diseases
Accuracy of FNAC in Thyroid Nodules Compared to to Surgical Specimen : QOC Experience
Thyroid gland diseases are the second most common endocrine disease following diabetes mellitus(1). Thyroid nodules are common disorders with a prevalence ranged from 4 to 7% in adult population, 5%-30% are malignant…
- Trial name
- Thyroid FNAC (NCT05521594)
- Testing
- Fine Needle Aspiration Cytology
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Qena Oncology Center
Thyroid Cancer
rhTSH-Thyroid Ablation With 1850 MBq of 131I
Most patients with differentiated thyroid carcinoma (DTC) are treated with therapeutic doses of radioiodine (131I) after initial surgery (total or near total thyroidectomy), aimed to destroy microscopic residual normal or tumoral…
- Trial name
- NCT00454077
- Testing
- radioiodine therapy after rhTSH
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Siena
Stomach Cancer, Colon Cancer
A Study With Health Educational Material on Health Promotion in Cancer Survivors
The purpose of this study is to provide educational material to promote screening for second primary cancer for the intervention group, or educational material to instruct appropriate use of dietary supplement for the control…
- Conditions
- Stomach Cancer, Colon Cancer, Thyroid Cancer, Breast Cancer
- Trial name
- NCT00948337
- Testing
- Brochure of Secondary Cancer Screening
- Where
- 2 sites in South Korea
- Volunteers
- 326 people
- Sponsor
- National Cancer Center, Korea
Thyroid Cancer, Thyroid Nodule
Delta Neutrophil Index and Neutrophil Lymphocyte Ratio in Thyroid Malignancy
Thyroid surgery is the most common surgical procedure among endocrine surgeries. It is performed in patients with suspected malignancy, patients diagnosed with malignancy, and for toxic nodular goiter [1].
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Diseases, Delta Neutrophyl Index
- Trial name
- NCT04425512
- Testing
- Complete Blood Count
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Papillary Thyroid Microcarcinoma, Thyroid Cancer
Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma
This is a single center prospective clinical trial with regard to efficacy and safety of radiofrequency ablation of papillary thyroid microcarcinoma.
- Trial name
- RFAforPTMC (NCT03432299)
- Testing
- RFA for PTMC
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Differentiated Thyroid Cancer
Iodine Uptake After a Low Iodine Diet
The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low…
- Trial name
- IULID (NCT05599139)
- Testing
- Low iodine diet
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- University Medical Center Groningen
Neoplasms
Depsipeptide to Treat Thyroid and Other Advanced Cancers
This phase I study will evaluate the experimental drug Romidepsinin patients with advanced cancer. The study will: 1) determine how well patients tolerate Romidepsin; 2) measure blood levels of Romidepsin during treatment; 3)…
- Trial name
- NCT00048334
- Testing
- Depsipeptide, FR901228, FK228
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Cancer Institute (NCI)
Thyroid Cancer
Assessment of CA 19-9 in Patients' With Thyroid Malignancies
Thyroid cancer is a rare disease that represents approximately 3.8% of all new cancer cases.Incidence of thyroid cancer in north Africa about 2.8% of all new cancer cases with mortality rate about 0.73%.Thyroid malignancies are…
- Trial name
- NCT05124938
- Testing
- Laboratory investigations for control: a-Complete blood count. b-Liver function test. c-kidney function test. d-thyroid-stimulating hormone,T3 and T4. e-Assessment of levels of CA19-9.
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cardiovascular Disorder, Chronic Kidney Disease
Cancer and Blood Pressure Management, CARISMA Study
This phase II trial studies how well intensive blood pressure management works in decreasing systolic blood pressure in patients with kidney or thyroid cancer that has spread to other places in the body (metastatic) who are…
- Conditions
- Cardiovascular Disorder, Chronic Kidney Disease, Metastatic Renal Cell Carcinoma, Metastatic Thyroid Gland Medullary Carcinoma
- Trial name
- NCT04467021
- Testing
- Best Practice, Blood Pressure Measurement, Clinical Management
- Where
- 25 sites in United States
- Volunteers
- 61 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Thyroid Nodules
Thyroid Artery Embolization for the Treatment of Compressive Goiters.
Very few studies have investigated TAE as a treatment for goiter with compressive symptoms. What is the efficacy and safety of TAE for the treatment of compressive goiters in a population ineligible for or refusing standard…
- Trial name
- TAE (NCT07360587)
- Testing
- Thyroid Artery Embolization
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Solid Tumor, Adult, Non-small Cell Lung Cancer
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NRAS-mutated advanced or metastatic solid tumors.
- Conditions
- Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
- Trial name
- NCT04913285
- Testing
- KIN-2787, KIN-2787 and binimetinib
- Where
- 48 sites in United States, Australia and 5 more
- Volunteers
- 400 people
- Sponsor
- Pierre Fabre Medicament
Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect
Thyroid Dysfunction and Nivolumab Reponse in NSCLC
This is an observational, retrospective and monocentric study, conducted at the university Hospital of Brest The primary objective is to assess the association between the occurrence of thyroid dysfunction in patients treated…
- Conditions
- Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect, Thyroid Dysfunction, Immune Checkpoint Inhibitor
- Trial name
- THYRONIVO (NCT04470440)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Brest
Thyroid Cancer, Tumor
MRG003 Added to Ongoing Treatment After Progression in EGFR-Positive Advanced Thyroid Cancer
This study will evaluate whether adding MRG003 to an ongoing treatment regimen can produce confirmed tumor shrinkage in patients with EGFR-positive advanced thyroid cancer whose cancer initially benefited from that regimen and…
- Conditions
- Thyroid Cancer, Tumor, Advanced Thyroid Carcinoma
- Trial name
- NCT07874321
- Testing
- Becotatug Vedotin (MRG003), Lenvatinib, Anti-PD-1 Inhibitor (Continuation of Prior Treatment)
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Cancer, Differentiated Thyroid Carcinoma
Effect of Lithium Carbonate on Low-Dose Radioiodine Therapy in Early Thyroid Cancer
This study will examine the safety and effectiveness of using lithium, which has been used to enhance the effectiveness of high-dose 131I, with a single low dose (30 mCi) of 131I for thyroid ablation in patients with recently…
- Trial name
- NCT00251316
- Testing
- Lithium Carbonate
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Papillary Thyroid Cancer
Overdiagnosis of Thyroid Cancer in the Marne and Ardennes Departments of France From 1975 to 2014
Introduction - Incidence of thyroid cancer has increased considerably in France in recent years, but the mortality rate has declined only slightly. Part of this increased incidence could be attributable to overdiagnosis.
- Trial name
- OTCancer (NCT03623516)
- Where
- France
- Volunteers
- 2,008 people
- Sponsor
- CHU de Reims
Thyroid Cancer
The Effects of Preoperative Prayer on Postoperative Quality of Recovery in Patients Undergoing Thyroidectomy
physiological end-point, incidence of adverse events, and changes in psychological status. In the past, physiological goals, major morbidity and mortality were used as indicators of recovery after surgery.
- Trial name
- NCT03375931
- Testing
- Prayer, non-prayer
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Yonsei University
Recurrent Thyroid Cancer
Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer
The goal of this study is to evaluate combined radioactive iodine (RAI, 131-I) and external beam radiotherapy (XRT) to optimize the radiation dose delivered to treat well differentiated thyroid cancers (DTC) with iodine-avid…
- Trial name
- NCT04892303
- Testing
- Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Papillary Thyroid Microcarcinoma
Radiofrequency Ablation Treatment of Low-Risk Papillary Thyroid Carcinomas
Researchers in this study aim to prove the safety and efficacy of radiofrequency ablation in the treatment of a carefully selected low-risk papillary thyroid microcarcinoma patient group.
- Trial name
- NCT07506161
- Testing
- Radiofrequency ablation alone
- Where
- Hungary
- Volunteers
- 27 people
- Sponsor
- Premier G Med Cardio Kft
Ovarian, Melanoma
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.
The present clinical trial is a dose comparison of a multi-component active immunotherapy designed to stimulate an immune reaction to specific tumor associated antigens which are highly expressed on a large number of solid…
- Conditions
- Ovarian, Melanoma, Renal, Prostate
- Trial name
- NCT00423254
- Testing
- PSMA/PRAME
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Mannkind Corporation
Thyroid Cancer
Camrelizumab and Apatinib for Neoadjuvant Therapy in Thyroid Cancer
To determine the efficacy and safety of anti-PD-1 antibody Camrelizumab combined with Apatinib for neoadjuvant therapy in locally advanced thyroid cancer.
- Trial name
- NCT04612894
- Testing
- Camrelizumab and Apatinib, surgery, core needle biopsy
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Fudan University