Clinical trials: Thyroid Metabolism
Thyroid Diseases, Hypocalcemia
Use of Prophylactic Steroids in the Prevention of Post-thyroidectomy Hypocalcaemia and Voice Dysfunction
Total thyroidectomy for benign surgical pathologies is associated with risks related to temporary hypocalcaemia and vocal quality dysfunction.
- Conditions
- Thyroid Diseases, Hypocalcemia, Vocal Cord Dysfunction
- Trial name
- NCT04752852
- Testing
- Dexamethasone
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Pakistan
Thyroid Metabolism
The Reduced Thyroid Function of the Premature Newborn: Relation With Molecular Changes in the Placenta and Maternal Thyroid Hormone Status and Neurodevelopmental Implications
Transient hypothyroxinemia of prematurity (THOP) is a typical entity of the preterm infant, affecting the majority of preterm infants, born less than 30 weeks of gestational age.
- Trial name
- NCT01466023
- Where
- Belgium
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Colon Cancer
Proteomic Analysis of Patients Undergoing Bariatric Surgery
The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery.
- Conditions
- Obesity, Colon Cancer, Thyroid Cancer, Esophageal Cancer
- Trial name
- NCT06787807
- Testing
- bariatric surgery
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Vitamin B12 Deficiency
Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
A review of the literature reveals that very few studies have assessed the potential co-existence of vitamin B12 deficiency due to gastric parietal cell autoantibodies. While Segal et al.
- Trial name
- NCT01876329
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Keesler Air Force Base Medical Center
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Celiac Disease in Children, Type 1 Diabetes
Prevention av Autoimmunitet Med Laktobaciller
The incidence of autoimmune diseases (celiac disease, type 1 diabetes, thyroid disease) have increased over the past 30 years. Although most autoimmune diseases have a strong link to different risk genes, the rapid increase is…
- Conditions
- Celiac Disease in Children, Type 1 Diabetes, Thyroid
- Trial name
- PAL (NCT04014660)
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy Volunteers
Thyroid and Fat Tissue Metabolism
This study will use a technique called microperfusion to examine how thyroid hormones are involved in fat metabolism. The thyroid gland produces two kinds of hormones: T3 and T4.
- Trial name
- NCT00312715
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Disease, Cancer
A Nutritarian Study to Evaluate the Effectiveness of Lifestyle Changes in Chronic Disease Prevention, Especially Cancer
The Nutritarian Women's Health Study (NWHS) is a long-term hybrid effectiveness-implementation study on the effect of the Nutritarian Diet on the occurrence, recurrence, and progression of chronic diseases (including all forms of…
- Conditions
- Chronic Disease, Cancer, Cardiovascular Diseases, Diabetes Mellitus
- Trial name
- NWHS (NCT03430141)
- Testing
- Nutritarian Diet-style
- Where
- United States
- Volunteers
- 2,898 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Abortion, Spontaneous, Pregnancy Complications
Relation Between Subclinical Hypothyroidism and Outcome of Pregnancy
Studies have demonstrated a relationship between subclinical hypothyroidism and obstetrics complications like preterm delivery, pre-eclampsia, placental abruption and stillbirth.
- Conditions
- Abortion, Spontaneous, Pregnancy Complications, Subclinical Hypothyroidism
- Trial name
- GravThyr (NCT01335802)
- Where
- Denmark
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Congenital Hypothyroidism, Metabolic Syndrome
Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism
We propose a multicenter prospective study to define the prevalence and severity score of metabolic syndrome in a prepubertal pediatric cohort with congenital hypothyroidism, compared to a healthy and normal-weight pediatric…
- Trial name
- IpoMet (NCT07126353)
- Testing
- prospective observational study (clinical, hormonal and auxological data)
- Where
- Italy
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Buzzi Children's Hospital
Hypocalcemia, Thyroid Diseases
Does Preoperative Calcium and Calcitriol Decrease Rates of Post Thyroidectomy Hypocalcemia?
The investigators are performing this study to determine if supplementation with calcium and calcitriol (vitamin D) before surgery decreases the rate of hypocalcemia (low calcium) after surgery.
- Trial name
- NCT03869398
- Testing
- Tums, Calcitriol
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Thyroid, Physical Activities
The Interaction Between Resting Metabolic Rate, Physical Activity and Thyroid Hormone in Females
This Study is focused on the interaction between resting metabolic rate (RMR), physical activity (PA), and thyroid hormones (TH).
- Conditions
- Thyroid, Physical Activities, Resting Energy Expenditure
- Trial name
- NCT06377943
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Obesity, Lipid Disorders
A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers
This is a clinical study to evaluate the safety, tolerability and pharmacokinetics of ZYT1, following oral administrations in healthy volunteers. The study shall be divided into four plans as given below: 1.
- Trial name
- NCT01543269
- Testing
- ZYT1
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zydus Lifesciences Limited
Thyroid Nodule, Insulin Resistance
Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules
It has been shown that insulin might be involved in the pathogenesis of thyroid growth. Objective To evaluate the impact of IR and metformin use on the volume of benign thyroid nodules (TNs).
- Trial name
- NCT03183752
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Universitário Clementino Fraga Filho
Metabolic Syndrome
Evaluation of the Pattern of Thyroid Dysfunctions in Patients With Metabolic Syndrome
The study on evaluation the pattern of TD in MetS population may help us to know the magnitude of overlap of these two disease entities and may highlight the importance of thyroid function tests in patients with MetS.
- Trial name
- NCT03214068
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Oral Lichen Planus, Thyroid Disease
Association Between Oral Lichen Planus and Thyroid Disease
The goal of this observational study is to determine the prevalence of thyroid disease in adults with oral lichen planus (OLP) treated at the Dental Hospital of the University of Barcelona (HOUB), and to evaluate the association…
- Trial name
- NCT06550154
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Contraception
Effects on Hemostasis, Lipids, Carbohydrate Metabolism, Adrenal & Thyroid Function of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG-EE (292004)(COMPLETED)(P05764)
The primary purpose of this study is to evaluate the effects of the combined oral contraceptive (COC) NOMAC-E2 on hemostasis, lipids, carbohydrate metabolism, adrenal function, and thyroid function.
- Trial name
- NCT00511355
- Testing
- NOMAC-E2, Levonorgestrel and Ethinyl Estradiol
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism
Growing up With the Young Endocrine Support System (YESS!)
Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out…
- Conditions
- Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism, Growth Hormone Deficiency, Combined Pituitary Hormone Deficiency
- Trial name
- YESS (NCT04252001)
- Testing
- YESS! game, Snake '97, Transition-toolkit
- Where
- 7 sites in Belgium, Netherlands and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Osteoporosis
Diagnosis of Decreased Bone Density by Dental Cone Beam Computed Tomography
The purpose of this study is to elucidate the role of Dental Cone Beam Computed Tomography (CBCT) in assessment of bone density.
- Trial name
- NCT02303340
- Testing
- Dual Energy X-ray Absorptiometry
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center