Clinical trials: Thyroid Nodule (Benign)
Thyroid Nodule
Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules
The purpose of this study is to prospectively compare percutaneous radiofrequency ablation (RFA) versus percutaneous laser ablation (LA) for the treatment of solid thyroid nodules.
- Trial name
- LARA (NCT02714946)
- Testing
- Percutaneous Laser Ablation, Percutaneous Radiofrequency Ablation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Hypothyroidism, Hyperthyroidism/Thyrotoxicosis
Evaluation of Different Diagnostic Therapeutic Strategies in Patients with Thyroid Pathology
Observational single-center prospective and retrospective, nonpharmacological, spontaneous cohort study.
- Conditions
- Hypothyroidism, Hyperthyroidism/Thyrotoxicosis, Thyroid Nodule (Benign), Thyroid Carcinoma
- Trial name
- NCT06779747
- Where
- Italy
- Volunteers
- 5,850 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Ablation Techniques, RFA, Ablation Treatment
Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT
We conduct a multi-institutional randomized control trial of RFA and MWA for the primary treatment of large, benign nodules. Adult patients >/=18 years of age who have a solitary thyroid nodule ≥20ml in volume who presents to 1)…
- Conditions
- Ablation Techniques, RFA, Ablation Treatment, Benign Thyroid Nodules, Local Anaesthesia
- Trial name
- NCT07804862
- Testing
- Radiofrequency ablation alone, Microwave ablation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Thyroid Nodules
RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study
The purpose of this observational research is to evaluate and compare clinical outcomes after treatment for symptomatic benign multinodular goiter (MNG) patients.
- Trial name
- NCT05189314
- Testing
- Thyroidectomy, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Columbia University
Benign Thyroid Nodule
Efficacy of a Spirulina Supplement for Amelioration of Benign ThYroid Nodules
Clinical trial with a double-blind, placebo-controlled, crossover design; enrolls approximately 30 euthyroid patients with benign thyroid nodules, who will receive for 6 weeks a spirulina-based supplement, and for another 6 weeks…
- Trial name
- ESSAY (NCT03535974)
- Testing
- Preparation with Spirulina
- Where
- Romania
- Volunteers
- 38 people
- Sponsor
- Fundatia Bio-Forum
Thyroid Diseases
The Feasibility and Safety of the TOETVA for Benign Thyroid Nodules
Thyroid surgery has been developed as a new technique for zero scar in surgery by applying transoral endoscopic thyroidectomy with sublingual approach.
- Trial name
- NCT03158961
- Testing
- Transoral endoscopic thyroidectomy vestibular approach
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Thyroid Nodules
The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules
1. To evaluate the clinical outcomes of ultrasound-guided thermal ablationfor the treatment of benign thyroid nodules; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided…
- Trial name
- NCT06340945
- Testing
- ultrasound-guided thermal ablation
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Thyroid Nodule
HIFU Reapplication in Benign Nodules
High Intensity Focused Ultrasound (HIFU) is a new approach in treating benign thyroid nodule without surgery. It is proven effective and safe relative to traditional surgery.
- Trial name
- NCT03331172
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 28 people
- Sponsor
- The University of Hong Kong
Benign Thyroid Nodule
Percutaneous Thermo-ablation for the Treatment of Benign Thyroid Nodules
The goal of this observational study is to learn if radiofrequency ablation (RFA), a minimally invasive thermoablation technique, can safely reduce symptoms and improve quality of life in adults with symptomatic benign thyroid…
- Trial name
- BIRRO-TA (NCT07237373)
- Testing
- Percutaneous radiofrequency ablation
- Where
- 3 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Thyroid Nodule, Diagnoses Disease
Diagnostic Significance of CTCs in Patients With Thyroid Nodules (Circulating Tumor Cells)
Thyroid nodule patients with suggestion of fine needle aspiration biopsy (FNAB) offered by ultrasound are enrolled in the study. CTCs tested by Optimizing method and FNAB will be performed simultaneously.
- Trial name
- CTCs (NCT03772496)
- Testing
- circulating tumor cells test, Fine needle aspiration biopsy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Low Risk, Papillary Thyroid Cancer
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
- Conditions
- Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
- Trial name
- NCT07140757
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Benign Thyroid Nodule
Cryoablation of Benign Thyroid Nodules: a Pilot Study
This study will evaluate the clinical response and safety of ultrasound guided percutaneous cryoablation in the treatment of benign thyroid nodules as an alternative to the surgery.
- Trial name
- NCT06014229
- Testing
- cryoablation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo General Hospital
Thyroid Nodule
The Application Value of Deep Learning-Based Nomograms in Benign-Malignant Discrimination of TI-RADS Category 4 Thyroid Nodules
This retrospective study focuses on benign and malignant classification of thyroid nodules using deep learning techniques and evaluates the value of deep learning based nomograms in the classification of TI-RADS category 4…
- Trial name
- NCT06258044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ma Zhe
Benign Thyroid Nodule, Suspicious Malignant Thyroid Nodule
A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy
To determine if transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a safe and effective procedure compared to traditional open thyroidectomy.
- Trial name
- NCT06225765
- Testing
- Transoral endoscopic thyroidectomy vestibular approach (TOETVA), Traditional Open Thyroidectomy
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Benign Thyroid Nodules
A Prospective Evaluation of High Intensity Focused Ultrasound (HIFU) in the Treatment of Benign Thyroid Nodules
To evaluate the short-term efficacy of high intensity focused ultrasound (HIFU) in the treatment of benign thyroid nodules
- Trial name
- NCT02658552
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 22 people
- Sponsor
- The University of Hong Kong
Thyroid Cancer, Nodule Solitary Thyroid
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
Patients with thyroid nodules are currently investigated with ultrasound with or without biopsy. Despite these investigations, a subset of patients remain "indeterminate" whereby a cancer can neither be diagnosed nor ruled out …
- Trial name
- NCT07124065
- Testing
- Diffuse reflectance spectroscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College London
Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma
Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule
This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells…
- Conditions
- Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma, Thyroid Gland Follicular Tumor of Uncertain Malignant Potential, Thyroid Gland Nodule
- Trial name
- NCT05003856
- Testing
- Quality-of-Life Assessment, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Benign Solitary Solid, Cystic Thyroid Nodules
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion.
- Trial name
- NCT00150150
- Testing
- Interstitial laser photocoagulation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Thyroid Nodule
Ultrasound-guided Percutaneous Microwave Ablation for Benign Thyroid Nodules
Percutaneous microwave ablation(MWA) was reported as an effective modality for the management of thyroid nodules(TNs). This study aims to validate MWA as a feasible approach for patients with TNs for whom surgery is…
- Trial name
- NCT03057925
- Testing
- Microwave Ablation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenjun Wu