Clinical trials: Thyroid Surgeries
Papillary Microcarcinoma of the Thyroid
Active Surveillance Versus Surgery in Thyroid Papillary Microcarcinoma
The primary objective of this study is to evaluate the outcome of two treatment approaches (immediate surgery or close follow-up) in patients with papillary thyroid microcarcinoma (mPTc) .
- Trial name
- MITICA (NCT04129281)
- Testing
- Surgery
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Naples
Thyroid Surgery
Visualization Versus Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerves in Thyroid Surgery
Some recent studies have shown that intraoperative neuromonitoring (IONM) can aid the recurrent laryngeal nerve (RLN) identification during thyroid surgery.
- Trial name
- NCT00661024
- Testing
- intraoperative RLN visualization, intraoperative neuromonitoring of the RLN
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Jagiellonian University
Thyroid Cancer
Assessing Patient Satisfaction and Confidence After Use of Educational Video to Augment Surgical Consent for Thyroid Surgery
This study looks at how a short educational video can help people better understand thyroid surgery. Patients who have thyroid nodules and need surgery will be part of the study.
- Trial name
- TISCAV (NCT06918223)
- Testing
- Thyroid Informed Surgical Consent Augmenting Video (TISCAV), Standard Consent
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Thyroid Cancer
Safety and Efficacy Study of Ultrasonic Coagulation Device and Bipolar Energy Sealing System
The aim of the study is to evaluate differences between use of Ultrasonic Coagulation Device (New Harmonic ACE™, Ethicon endo-surgery) and Bipolar Energy Sealing System (LigaSure Precise™, Covidien) in surgery for thyroid cancer.
- Trial name
- UCBEST (NCT01565486)
- Testing
- Ultrasonic coagulation device (Harmonic ACE® scalpel), bipolar energy sealing system (LigaSure Precise)
- Where
- South Korea
- Volunteers
- 304 people
- Sponsor
- Seoul St. Mary's Hospital
Thyroid Disease, Recurrent Laryngeal Nerve Injury
Low-Current Stimulation for Recurrent Laryngeal Nerve Protection During Thyroid Surgery
This single-center prospective randomized interventional study evaluated whether intraoperative low-current stimulation could assist recurrent laryngeal nerve localization and reduce temporary recurrent laryngeal nerve injury…
- Trial name
- NCT07706699
- Testing
- 3 mA low-current stimulation-assisted recurrent laryngeal nerve identification, 5 mA low-current stimulation-assisted recurrent laryngeal nerve identification
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Thyroid Tumor
Effect of Modified Endotracheal Intubation Protocol Combined With Early Oral Intake on Postoperative Recovery Quality in Thyroid and Parathyroid Surgery
The purpose of this study is to assess the effect of modified endotracheal intubation procedure combined with early oral intake on postoperative recovery quality of patients, so as to further optimize the ERAS（enhanced recovery…
- Trial name
- NCT05624463
- Testing
- Modified intubation protocol, Conventional intubation protocol, Early resumption of oral intake
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Thyroid, Surgery
A Deep Learning Method to Predict Difficult Laryngoscopy Using Cervical Spine X-ray Image
An unanticipated difficult laryngoscopy is associated with serious airway-related complications. The investigators developed a deep learning-based model that predicts a difficult laryngoscopy (Cormack-Lehane grade 3-4) from a…
- Conditions
- Thyroid, Surgery, Intubation; Difficult or Failed
- Trial name
- NCT05176184
- Testing
- A deep learning model for predicting a difficult laryngoscopy based on a cervical spine lateral X-ray image
- Where
- South Korea
- Volunteers
- 367 people
- Sponsor
- Seoul National University Hospital
Thyroid Cancer, Thyroid and Parathyroid Surgery
The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery
THE EFFECT OF HEAD POSİTİON ON THE OPTİC NERVE SHEATH DİAMETER İN PATİENTS DURİNG THYROİD SURGERY
- Conditions
- Thyroid Cancer, Thyroid and Parathyroid Surgery, Thyroid Adenoma
- Trial name
- NCT07298187
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Thyroid Nodules
Realtime-Elastography (RTE) and Thyroid Nodules
The study is an open, prospective multicenter study. According to the statistical sample size calculation 593 patients with thyroid nodules ≥ 5mm in size will be included in the study.
- Trial name
- NCT01609946
- Testing
- Realtime-Elastography, linear ultrasound probe, Hitachi EUB-900, Japan, Cytology (FNAB) or Surgery
- Where
- 10 sites in Germany
- Volunteers
- 602 people
- Sponsor
- Johannes Vermehren
Carcinoma, Papillary, Follicular
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery
The paralysis of the external branch of superior laryngeal nerves after thyroid surgery is known to be a common complication resulting in poor quality of life.
- Trial name
- NCT03773120
- Testing
- Using Neuromonitoring to find EBSLN
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Thyroid Cancer, Thyroid Nodule
Surgical Competency for Robot-Assisted Thyroidectomy: Construction and Validation of a Robotic Thyroidectomy Assessment Score (RTAS)
To develop and validate a structured scoring tool (robotic thyroidectomy assessment score, RTAS) for assessing and quantifying surgical performance in robotic thyroidectomy (RT).
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Diseases, Thyroid Cancer, Papillary
- Trial name
- NCT06730321
- Testing
- Observations on clinicopathological factors influencing the assessment score of surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai 6th People's Hospital
Nitroprusside, Thyroid Hormones
Clinical Study Investigating the Effect of Sodium Nitroprusside Infusion on Thyroidal Function
Whether use of SNP during cardiac surgery has any effect on thyroid function has not yet been investigated in humans. The aim of this study was to investigate the effects of SNP administration during the rewarming period of…
- Trial name
- NCT00636584
- Testing
- sodium nitroprusside
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Kavaklıdere Umut Hospital
Thyroid Surgery Intraoperative Nerve Monitoring (IONM) Recurrent Laryngeal Nerve Function Dexmedetomidine vs Midazolam (Anesthetic Agents)
EFFECT OF DEXMEDETOMİDİNE ON RECURRENT LARYNGEAL NERVE MONİTORİNG: A COMPARATİVE STUDY WİTH MİDAZOLAM
This prospective observational study evaluated the effect of dexmedetomidine compared with midazolam on intraoperative monitoring of the recurrent laryngeal nerve during thyroid surgery.
- Trial name
- DEX-RLN (NCT07195214)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Amasya University
Papillary Thyroid Cancer
Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery
Dear Patient, You are invited to participate in a clinical study investigating the Application of Mitoxantrone Hydrochloride Injection for Lymphatic Tracing in Transoral Robotic Thyroid Cancer Surgery.
- Trial name
- MHI (NCT07354698)
- Testing
- mitoxantrone hydrochloride injection
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Graves Ophthalmopathy
Analysis Between the Results of Two Surgical Techniques of Orbital Decompression in Patients With Graves Orbitopathy
Randomized prospective clinical trial, aiming to compare two techniques of orbital decompression. Patients with Graves orbitopathy in the inactive phase for at least 6 months will be divided in two groups; one group will be…
- Trial name
- NCT03278964
- Testing
- Orbital decompression
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo General Hospital
Thyroid Surgery
The Effect of the Application of Head Mounted Magnifying Glasses on Postoperative PTH Changes in Thyroid Surgery: Stage II
This study is a prospective research. This study aims to investigate and follow up patients who undergo open thyroidectomy in the Department of Breast and Thyroid Surgery at Shandong Provincial Hospital from January 2020 to…
- Trial name
- NCT06838728
- Testing
- Head Mounted Magnifying Glasses
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shandong Provincial Hospital
Thyroid Function, Obesity
The Effect of Bariatric Surgery on Thyroid Function and Morphology
The aim is to evaluate the effect of dramatic weight loss after bariatric surgery on thyroid function (thyroid hormone levels and particulary morphological changes) in the short and long-term setting of a cross-sectional study.
- Trial name
- NCT00871130
- Testing
- Bariatric surgery
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hyperthyroidism, Thyroidectomy
The Application of Rapid PTH Test Paper in Operation of Hyperparathyroidism
The half-life of the parathyroid hormone is about 4min, blood pth test is use in operation to confirm that parathyroid tumor is removed. but the blood pth test is time consuming and unpractical in most of hospital.
- Conditions
- Hyperthyroidism, Thyroidectomy, PTH, Immunochromatographic
- Trial name
- NCT03434067
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Bo Wang,MD
Thyroid Associated Orbitopathy
Changes in Orbital Macrovascular and Intraocular Microvascular Blood Flow After Orbital Decompression Surgery in Patients With Thyroid Eye Disease
This study aims to evaluate the effects of balanced orbital decompression surgery in patients with inactive thyroid-associated orbitopathy.
- Trial name
- BOD-VASC (NCT07393230)
- Testing
- Balanced Orbital Decompression Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Thyroidectomy
Superficial, Cervical Block in Thyroid Surgery, a Randomized Controlled Trial
The study investigates the impact on post-operative pain of the superficial cervical block with bupivacaine combined with subcutaneous infiltration of the incisional area in thyroid surgery under general anesthesia.
- Trial name
- NCT00472446
- Testing
- bilateral superficial cervical block
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- Cantonal Hospital of St. Gallen