Clinical trials: Tic Douloureux
Trigeminal Neuralgia
Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
A placebo-controlled, single-blind study to evaluate the safety and preliminary efficacy of nasal carbon dioxide for the symptomatic treatment of classical trigeminal neuralgia.
- Trial name
- NCT02473016
- Testing
- Carbon Dioxide Drug Delivery System (CDDS)
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Capnia, Inc.
Trigeminal Neuralgia
Defining Core Outcome Sets in Trigeminal Neuralgia
The aim of this study is to determine what patients with trigeminal neuralgia (TN), clinicians and researchers in the field, consider to be the most important outcomes to be expected after undergoing treatment for trigeminal…
- Trial name
- TRINCOS (NCT04272385)
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Trigeminal Neuralgia
The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing…
- Trial name
- NCT06977932
- Testing
- Carbarmazepine, Electroacupuncture
- Volunteers
- 126 people
- Sponsor
- Yuanyuan Wu
Trigeminal Neuralgia
A Phase IIa Withdrawal Study of CNV1014802 in Patients With Trigeminal Neuralgia
This is a double-blind, randomized withdrawal study comparing CNV1014802 with placebo in patients with trigeminal neuralgia who have successfully responded to CNV1014802 in an initial open-label phase.
- Trial name
- NCT01540630
- Testing
- CNV1014802
- Where
- United Kingdom
- Volunteers
- 67 people
- Sponsor
- Biogen
Trigeminal Neuralgia
Treatment of Recurrent Trigeminal Neuralgia by Using Extended Duration of Pulsed Radiofrequency
Forty patients with history of recurrent TN were recruited in Assiut University Hospitals, Pain Unit from 2012 to 2017. Before the study, all patients were given adequate and informative data about the nature of the study…
- Trial name
- NCT03396406
- Testing
- Pulsed radiofrequency (PRF), thermocoagulation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Trigeminal Neuralgia
Effect of Non-invasive Photobiomodulation Therapies in Patients With Trigeminal Neuralgia
The aim of this study was to compare the effectiveness of two different photobiomodulation (PBM) therapies as an alternative to medical treatment to reduce pain and improve quality of life in patients with trigeminal neuralgia…
- Trial name
- NCT06440356
- Testing
- laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Trigeminal Neuralgia Treated by Radiosurgery
Impact of Individual Radiosensitivity on Late Toxicities of Radiosurgery in Essential Trigeminal Neuralgia
Trigeminal neuralgia is intense, electric-shock-like facial pain, most often triggered by touch, chewing or speech. It results from dysfunction of the trigeminal nerve, the 5th cranial nerve.
- Trial name
- TRITON (NCT06863324)
- Testing
- Radiation induced Lymphocyte Apoptosis diagnostic test
- Where
- 2 sites in France, Monaco
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Trigeminal Neuralgia
Intravenous Lacosamide for the Treatment of Acute Pain in Trigeminal Neuralgia
This prospective observational study evaluates the effectiveness and safety of intravenous lacosamide as a rescue treatment for acute pain in patients presenting to the emergency department with trigeminal neuralgia
- Trial name
- NCT06851910
- Testing
- Lacosamide
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitari de Bellvitge
Trigeminal Neuralgia
Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia
Trigeminal neuralgia is a debilitating neurological condition, affecting quality of life in most affected patients. Carbamazepine has traditionally been used for the management of this condition, but it has a moderate…
- Trial name
- NCT06849219
- Testing
- Oxcarbazepine, Carbamazepine
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Trigeminal Neuralgia
Greater Occipital Nerve and Cervical Region Injection in Patients With Trigeminal Neuralgia
The aim of this study is to investigate the efficacy of greater occipital nerve block and cervical injections with lidocaine
- Trial name
- NCT04505280
- Testing
- Lidocaine 1% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Neoplasms, Arteriovenous Malformation of Central Nervous System
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time…
- Conditions
- Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia
- Trial name
- NCT01885299
- Testing
- SRS/SBRT
- Where
- 13 sites in United States
- Volunteers
- 50,000 people
- Sponsor
- The Radiosurgery Society
Trigeminal Neuralgia
Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia
Trigeminal neuralgia or tic douloureux is severe, often debilitating, facial pain that significantly impairs the patient's quality of life and health.
- Trial name
- NCT01364272
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Trigeminal Neuralgia
MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia
The purpose of this study is to assess the safety and effectiveness of MRI-guided focused ultrasound (MRgFUS) for treating Trigeminal Neuralgia.
- Trial name
- NCT04579692
- Testing
- ExAblate Transcranial treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Trigeminal Neuralgia
RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia
The goal of this study is to evaluate if KRIYA-748 (RP-008) is safe, tolerable, and preliminary effective in treating trigeminal neuralgia (TN) when used in combination with varenicline tartrate.
- Trial name
- RELIEF (NCT07596485)
- Testing
- RP-008, Varenicline tartrate
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Kriya Therapeutics, Inc.
Pain, Chronic
the Value of Sensory Index in Trigeminal Neuralgia
Interventional therapies for Trigeminal Neuralgia are of variable efficacy and safety, and have different results for different periods of time before the recurrence of symptoms.
- Trial name
- NCT04864964
- Testing
- combined conventional and pulsed radiofrequency (CCPRF)
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- National Cancer Institute, Egypt
Effectiveness of Drugs Was Compared for Treating Trigeminal Neuralgia, Pain
To Evaluate Efficacy of Monotherapy of Oxcarbazepine Versus Combination of Gabapentin With Oxcarbazepine in the Management of Trigeminal Neuralgia
ABSTRACT: Objective: This study evaluates the effectiveness of oxcarbazepine monotherapy with the combination of gabapentin and oxcarbazepine in managing trigeminal neuralgia(TN).
- Conditions
- Effectiveness of Drugs Was Compared for Treating Trigeminal Neuralgia, Pain, Pain Management
- Trial name
- NCT07625410
- Testing
- oxcarbamezapine(300 mg twice daily), combination therapy(oxcarbamezapine 300 mg twice daily and gabapentine)
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Rehman Medical Institute - RMI
Trigeminal Neuralgia (TN)
Developing a Clinical Prediction Model for Adverse Outcomes in Percutaneous Trigeminal Ganglion Balloon Compression
This clinical study aims to investigate adverse outcomes following percutaneous balloon compression (PBC) of the trigeminal ganglion, establish a predictive model, and assess the probability of postoperative complications.The…
- Trial name
- NCT06998420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Nantong University
Trigeminal Neuralgia
Efficacy, Safety, and Tolerability of SR750 in Patients With Trigeminal Neuralgia
The goal of this clinical trial is to evaluate the efficacy，safety and tolerability of SR750 in patients with trigeminal neuralgia (TN).
- Trial name
- NCT06571448
- Testing
- SR750 tablet
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Shanghai SIMR Biotechnology Co., Ltd.
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust