Clinical trials: Time in Range
Diabetes type1, Diabetes Mellitus, Type 1
Does the Use of Fiasp vs. Asp Lead to the Prolonged TIR in Children With Type 1 Diabetes?
The aim of the study is to assess whether the implementation of faster insulin aspart in children with Type 1 diabetes treated with intensive insulin therapy with the use of an insulin pump and using Real Time Continuous Glucose…
- Trial name
- NCT04772729
- Testing
- Insulin faster aspart (Fiasp, Novo Nordisk)
- Volunteers
- 77 people
- Sponsor
- Medical University of Warsaw
Diabetic Foot, Diabetes Type 2 With Diabetic Ulcer of Toe, Skin Breakdown
CGM and DFU Healing Post-discharge
The purpose of this study is to look at the benefits of using a Continuous Glucose Monitoring (CGM) system compared with standard-of-care testing for patients with type 2 diabetes and diabetic foot ulcers (DFU) and how this will…
- Trial name
- NCT06054659
- Testing
- Real Time Continuous Glucose Monitoring (rt-CGM), Fingerstick blood glucose (FBG) monitoring, Diabetes Education
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- Emory University
Type 2 Diabetes
IGNITE (Impact of Glucose moNitoring and nutrItion on Time in rangE)
The purpose of this study is to learn whether there is a difference in the amount of time glucose (blood sugar) stays within a target range (glucose 70 - 180 mg/dl) when using either continuous glucose monitoring (CGM) or…
- Trial name
- IGNITE (NCT05516797)
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- HealthPartners Institute
Type 1 Diabetes
Ultrarapid Insulin Administered by a Bihormonal Closed Loop System in Patients With Type 1 Diabetes
The main objective is to determine the efficacy of Lyumjev (insulin) in a bi-hormonal reactive closed loop system for automated glucose regulation (artificial pancreas; AP®) in patients with diabetes mellitus type 1.
- Trial name
- FAST 1 (NCT05508061)
- Testing
- Insulin Lispro Cartridge [Lyumjev], Insulin Lispro Cartridge
- Where
- 3 sites in Netherlands
- Volunteers
- 12 people
- Sponsor
- Inreda Diabetic B.V.
Dialysis, Chronic Kidney Disease
Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease
The goal of this this randomized, clinical trial is to test an automated insulin delivery system (AID) in people with type 1 or type 2 diabetes who are on hemodialysis, peritoneal dialysis, or have advanced chronic kidney disease…
- Conditions
- Dialysis, Chronic Kidney Disease, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT06330194
- Testing
- 2nd Generation Automated Insulin Delivery (AID) system
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Steno Diabetes Center Copenhagen
Atrial Fibrillation
Evaluation of a Pharmacogenetic-based Warfarin Dosing Algorithm in Patients
Background: Time in therapeutic range (TTR) is a measurement of quality of warfarin therapy and lower TTR values (<50%) are associated with greater risk of thromboembolic and bleeding events.
- Trial name
- NCT02592980
- Testing
- Pharmacogenetic anticoagulation, Traditional anticoagulation
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- University of Sao Paulo General Hospital
Type1diabetes
Happy Bob App in 9-13 Year-old Children
The purpose of the study is to evaluate the effectiveness of the Happy Bob -application on glycemic control in children aged 9-13 years with type 1 diabetes.
- Trial name
- NCT05663606
- Testing
- Happy Bob, CGM
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Type 2 Diabetes Mellitus (T2DM)
Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes
The goal of this clinical trial is to learn if early combination with two antidiabetic drugs further improves blood glucose control compared to a single drug regimen in adults with short duration of type 2 diabetes.
- Trial name
- E-SEMPA (NCT06613854)
- Testing
- Oral semaglutide, Empagliflozin 10 mg
- Where
- Slovenia
- Volunteers
- 90 people
- Sponsor
- University Medical Centre Ljubljana
Type 2 Diabetic Patients
A Study Comparing Degu Insulin Liraglutide Injection With Premixed Insulin on the Prognosis of Diabetes Mellitus
A randomized open, positive parallel controlled clinical study design was adopted. Participants were randomly assigned 1:1 according to inclusion criteria and exclusion criteria into two treatment regiments: Delu insulin…
- Trial name
- TLI vs PMI (NCT06925334)
- Testing
- Degludec insulin
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
type1diabetes
Diabetes in African Youth
This RCT aims to improve T1D care in East African children and young adults by testing the hypothesis that enabling patients to continuously monitor glucose levels with flash CGM technology will improve glucose time-in-range…
- Trial name
- NCT05454176
- Testing
- Libre 2, Device for SMBG and Libre Pro
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Minnesota
Type 1 Diabetes (T1D)
Mealtime or Post-meal Dosing of URLi in Medtronic 780G Hybrid Closed Loop System
This is a pilot study to compare premeal to postmeal dosing of ultra rapid lispro insulin (URLi) used in a MiniMed 780G system hybrid closed loop system.
- Trial name
- NCT06600776
- Testing
- Ultra Rapid Lispro (URLi), Insulin pump with continuous glucose monitoring (CGM)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Type 1 Diabetic Nephropathy
The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy
Diabetic nephropathy (DN) is one of the most frequent microvascular complications of diabetes mellitus, affecting 25 to 40% of patients with type 1 diabetes (T1DM).
- Trial name
- NCT06115460
- Testing
- oral sitagliptin supplementation
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Diabetes Mellitus, Type 1
Study Comparing Prandial Insulin Aspart vs. Technosphere Insulin in Patients With Type 1 Diabetes on Multiple Daily Injections: Investigator-Initiated A Real-life Pilot Study-STAT Study
This is an investigator-initiated, prospective, randomized, multicenter, parallel, open-label, pilot clinical trial evaluating the efficacy of TI for PPBG, PPGE, and time-in-range on CGM download in patients with T1D.
- Trial name
- STAT (NCT03143816)
- Testing
- Technosphere insulin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
T1DM
RCT for Evaluation of Insulin Administration,While Using the iPORT System
Type 1 diabetes is the most common chronic pediatric autoimmune disease, with a rising incidence rate in recent years around the world and in Israel Management includes multiple daily capillary glucose measurements by finger…
- Trial name
- NCT04421001
- Testing
- I-port use
- Volunteers
- 35 people
- Sponsor
- Assaf-Harofeh Medical Center
Atrial Fibrillation and Flutter, Mechanical Mitral Valve Prosthesis
Impact of Education Level on Clinical Outcomes in Self-INR Managed Patients
Oral anticoagulation (OAC) is indicated in a wide variety of clinical conditions including atrial fibrillation (AF), mechanical valve prosthesis (MVP), deep vein thrombosis and pulmonary embolism.
- Trial name
- NCT06187155
- Testing
- INR self-management
- Where
- Egypt
- Volunteers
- 586 people
- Sponsor
- Cairo University
Type 1 Diabetes Mellitis, Celiac Disease
Metabolic Control and Glycemic Variability in Type 1 Diabetes and Celiac Disease
This is an observational, retrospective study focused on differences of time-in-range and glycemic variability between a cohort of patients with both type 1 diabetes and celiac disease, and a cohort of patients with only type 1…
- Trial name
- NCT06717841
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Continuous Glucose Monitoring
Time in Range (TIR) and Time Below Range (TBR) in Insulin-Treated Elderly Patients With Type 2 Diabetes
Prospective observational cohort study. Elderly patients >65 years with type 2 diabetes mellitus (T2DM) on insulin therapy and HbA1c between 7% and 9%, with or without oral agents, will be identified from medical records and…
- Trial name
- NCT04411277
- Testing
- Application of the FreeStyle Libre Flash Glucose CGM., InBody 270 multifrequency bioimpedance
- Where
- Brazil
- Volunteers
- 71 people
- Sponsor
- Cline Research Center
Diabetes Mellitus, Type 1
Is Real-time CGM Superior to Flash Glucose Monitoring in Real Life Study (CORRIDA LIFE)
The aim of the investigator's study is to compare real-time continuous glucose monitoring (rt-CGM) and flash glucose monitoring (FGM) in adult patients with Type 1 Diabetes (T1D) in real life practice during 24 weeks of follow-up.
- Trial name
- NCT04759495
- Testing
- Continuous Glucose Monitoring Dexcom G5 and G6 system (real-time continuous glucose monitoring), Continuous Glucose Monitoring FreeStyle Libre Flash system (flash glucose monitoring)
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- Charles University, Czech Republic
Diabetes type1
Simple Initiation of Advanced Hybrid Closed Loop System
Background and Aim. The new and advanced hybrid closed loop (AHCL) system MiniMed 780G automatically adjusts basal insulin delivery in addition to automated bolus corrections, based on continuous glucose monitoring (CGM)…
- Trial name
- 780GGS (NCT05069727)
- Testing
- Regular Protocol with advanced carbohydrate counting, Simplified Protocol with fixed carbohydrate content
- Where
- Qatar
- Volunteers
- 34 people
- Sponsor
- Sidra Medicine
Type 1 Diabetes Mellitus
A Randomized Control Trial in People With Type 1 Diabetes Who Will Fast Ramadan: Does Insulin Timing and Dose Matter?
Fasting Ramadan is one of the five pillars of Islam and requested only from healthy adults to abstain from eating and drinking from sunrise to sunset.
- Trial name
- NCT04135248
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Dasman Diabetes Institute