Clinical trials: Tissue Grafts
Immediate Implant, Connective Tissue Graft
Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial
Peri-implant soft tissue dehiscences represent a common complication in implant dentistry, often leading to esthetic and functional challenges.
- Trial name
- NCT06588998
- Testing
- Xengenic Cortical membranes, connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Amr Anwar Mohamed Ellithy Yousef
Peri-implant Soft Tissue Deficiency, Insufficient Peri-implant Keratinized Tissue
CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation
This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix.
- Trial name
- NCT07371481
- Testing
- Collagen Matrix, Connective Tissue Graft
- Where
- Vietnam
- Volunteers
- 46 people
- Sponsor
- Hanoi Medical University
Heel Fat Pad Atrophy
Fat Grafting and Retention for Heel Fat Pad Atrophy
Plantar heel pain is the most common problem of the foot. Plantar fasciitis is the leading cause of this pain, accounting for 11-15% of all foot symptoms seeking professional care, and occurs in 10% of the US population.
- Trial name
- NCT02465333
- Testing
- Heel Fat Grafting
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pittsburgh
Gingival Recession
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015).
- Trial name
- NCT06146855
- Testing
- Tunneling procedure with Amnion Membrane, Tunneling procedure with De-epithelialized Free Gingival Graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-implant Mucosa Thickness, Peri-implant Mucosa Width
Soft Tissue Management in Peri-Implant Regions
Background:This study aimed to compare the effect of ribose cross-linked thick collagen membrane (RCCM) with that of subepithelial connective tissue graft (CTG) in sites with soft tissue deficiency in the horizontal aspect around…
- Conditions
- Peri-implant Mucosa Thickness, Peri-implant Mucosa Width, Peri-Implant Tissues
- Trial name
- NCT06880185
- Testing
- Connective Tissue Graft, Ribose Cross-Linked Thick Collagen Membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ömer Alperen Kırmızıgül
Graft vs Host Disease, Congenital Aniridia
Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation
The ARGOS-IO pressure sensor is intended to be implanted in the human eye in combination with Boston Keratoprosthesis (BKPro) surgery and to remain in place indefinitely.
- Conditions
- Graft vs Host Disease, Congenital Aniridia, Chemical Burns, Stevens-Johnson Syndrome
- Trial name
- NCT02945176
- Testing
- ARGOS-IO system
- Where
- 2 sites in Germany
- Volunteers
- 13 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Skin Ulcer
Treatment of Hypertensive Leg Ulcer by Adipose Tissue Grafting
The hypertensive leg ulcer is a very painful leg related to acute skin microangiopathy. It occurs in patients older than 60 years followed for hypertension.
- Trial name
- Angiolipo (NCT01932021)
- Testing
- adipose tissue grafting
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Dental Implants
The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft
Dental implant placement and simultaneous grafting using one layer gum graft will result in the same facial ridge contour and soft tissue thickness as one layer of gum graft plus bone graft.
- Trial name
- NCT02139748
- Testing
- Dental Implant & ADM, Dental Implant & ADM & bone xenograft
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Graft Versus Host Disease, Leukemia
Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer
RATIONALE: Umbilical cord blood transplantation may allow doctors to give higher doses of chemotherapy or radiation therapy and kill more cancer cells.
- Conditions
- Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes
- Trial name
- NCT00003335
- Testing
- anti-thymocyte globulin, busulfan, cyclosporine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer
Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation
RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill tumor cells.
- Trial name
- NCT00003538
- Testing
- graft versus host disease prophylaxis/therapy, allogeneic bone marrow transplantation
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Gingival Recession
Evaluation of the Treatment of Multiple Gingival Recession Using Modified Coronally Advanced Tunnel With Subepithelial Connective Tissue Graft Depending on the Positioning of the Graft
Microsurgical coronally advanced tunnel procedures using subepithelial connective tissue grafts (sCTG) are predictable for healing of multiple adjacent type 1 and 2 gingival recessions (RT1 and RT2).
- Trial name
- NCT06366022
- Testing
- The tunnel technique for root coverage with CTG with inner side of the graft, The tunnel technique for root coverage with CTG with outer side of the graft
- Where
- Poland
- Volunteers
- 21 people
- Sponsor
- Medical University of Warsaw
Nasal Septum Perforation
Nasal Septal Flap for Donor Site Reconstruction
The purpose of this study is to demonstrate the utility of porcine small intestinal submucosa (SIS) as a graft material that may aid in the natural healing process of freshly exposed bone and cartilage in the nasal cavity.
- Trial name
- NCT03159624
- Testing
- Biodesign™ SIS graft, Doyle silastic sheet
- Volunteers
- 47 people
- Sponsor
- University of Alabama at Birmingham
Gingival Recession, Localized
Er,Cr:YSGG Laser For Recipient Bed Bio-modification And Connective Tissue Harvesting in Treatment of Gingival Recession
A clinical and radiographic evaluation of using Erbium, Chromium, Scandium, Gallium and Garnet (Er,Cr:YSGG) laser in recipient site bio-modification and de-epithelialized connective tissue graft harvesting compared to…
- Trial name
- NCT03200392
- Testing
- laser root surface conditioning & laser DGG harvesting, laser root surface conditioning & blade DGG harvesting, blade DGG harvesting
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr International University
Thoracic Surgery, Cardiac Surgery
Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients
Rationale: It is well known that distinctly abnormal blood potassium values can cause serious complications such as cardiac arrhythmias.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Critically Ill
- Trial name
- GRIP-COMPASS (NCT01085071)
- Testing
- Potassium Chloride
- Where
- Netherlands
- Volunteers
- 1,225 people
- Sponsor
- University Medical Center Groningen
Gingival Recession
Evaluation of the Modified VISTA Technique Using ALB-PRF vs CTG in the Treatment of Multiple Miller Class III Recessions
treatment of miller class III RT2 gingival recession using modified vista technique using connective tissue graft vs albumin PRF
- Trial name
- NCT06643507
- Testing
- Connective tissue graft, ALB-PRF
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mucositis
Surgical Protocol for Prevention of Mucositis
The main goal of implant therapy is to obtain long-term peri-implant health. Among local risk factors in the etiology of peri-implant diseases the absence of keratinized tissue (KT) around the implant has been reported.
- Trial name
- NCT04628520
- Testing
- Free gingival graft, Collagen matrix, Maintenance
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing
Cyanoacrylate Tissue Adhesives Versus Silk Suture at the Palatal Donor Site of Sub Epithelial Connective Tissue Graft
Subepithelial connective tissue grafts (CTG) are considered the gold standard procedure with proven clinical success when it comes to gingival augmentation aims to to improve periodontal health, which can enhance the long-term…
- Trial name
- NCT04780360
- Testing
- Cayanoacrylate tissue adhesives, Silk suture
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Free Gingival Graft, Free Gingival Graft Volume Change
Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Posterior Mandibular Implant
Presence of keratinized tissue (KT) around dental implants, plays a crucial role in stability and health of peri-implant tissues.
- Conditions
- Free Gingival Graft, Free Gingival Graft Volume Change, Keratinized Tissue
- Trial name
- NCT06645925
- Testing
- One Step Protocol, Two Steps Protocol
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr International University
Vitiligo
Comparison of Surgical Methods on Resistant Sites in Stable Vitiligo Patients
Comparing the Efficacy of Three Different Surgical Methods on Resistant Sites in Stable Vitiligo.
- Trial name
- NCT03717025
- Testing
- SUCTION BLISTER EPIDERMAL GRAFTING, MINI PUNCH GRAFTING, NON CULTURED EPIDERMAL CELL SUSPENSION
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh