Clinical trials: Tissue Preservation
Alveolar Ridge Augmentation
PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction
This clinical trial aims to compare the efficacy and safety of applying "PeptiCol EZgraft" in extraction socket preservation procedures against "Regenomer," in terms of reducing the amount of alveolar bone change during the…
- Trial name
- NCT06783660
- Testing
- Peptide-loaded collagen sponge and collagen gel complex, Collagen sponge
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- NIBEC Co., Ltd.
Comparative Study
Soft Tissue Graft Versus Acellular Dermal Matrix in Preservation of Buccal Plate of Bone
Comparative study between 2 groups to assess the feasibility of using Acellular dermal matrix vs Soft tissue Graft after immediate implant placement
- Trial name
- NCT06229561
- Testing
- Acellular Dermal Matrix
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Breast Neoplasm Female
Developing a Web-based Shared Decision-making Tool for Fertility Preservation
The objective of this study was to develop a web-based, shared decision-making (SDM) tool for helping patients with breast cancer make decisions on fertility preservation.
- Trial name
- NCT04602910
- Testing
- a web-based shared decision-making tool
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Osteogenesis Imperfecta, Total Absence of Permanent Teeth
Site Preservation After Tooth Extraction
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage.
- Conditions
- Osteogenesis Imperfecta, Total Absence of Permanent Teeth, Tooth Socket
- Trial name
- NCT05258019
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Diabetic Foot, Lower Limb Wound
Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation Study
University Health Network (UHN), working together with local primary care practitioners, patients, and community healthcare services is developing a Diabetic Foot Care and Limb Preservation Care pathway.
- Conditions
- Diabetic Foot, Lower Limb Wound, Diabetes, Amputation
- Trial name
- NCT05446337
- Testing
- Open-Ended Semi-Structured Interview
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Dental Implant Placement, Socket Shield Technique Implant Placement
: SOCKET SHIELD TECHNIQUE VERSUS EMPTY SOCKET TECHNIQUE
To evaluate the clinical and radiographic outcomes of socket shield technique compared with conventional immediate implant placement.
- Trial name
- NCT02992366
- Testing
- implant placement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Augmentation, Connective Tissue
Ridge Preservation Using Different Techniques
Soft tissue contour and radiographic evaluation of alveolar ridge preservation using different techniques Background: Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process which influences…
- Conditions
- Alveolar Ridge Augmentation, Connective Tissue, Tooth Extraction, Membranes; Retained
- Trial name
- NCT05892016
- Testing
- Alveolar ridge preservation
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Socket Preservation
Clinical and Radiographic of the Effect of Socket Preservation Using the Roll Pedicle Connective Tissue Graft With Bovine Bone: A Case Series Trial.
After tooth extraction, the residual alveolar ridge generally provides limited bone volume because of ongoing, progressive bone resorption.
- Trial name
- NCT05255341
- Testing
- roll pedicle connective tissue graft with bovine bone
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer, HER2-negative Breast Cancer
Clinical Study of Breast Conserving Surgery Combined With Intraoperative Radiotherapy for Early Breast Cancer
A Single-center, open, prospective study，for analyzing the local recurrence rate, the incidence of incision complications and the aesthetic effect of intraoperative radiotherapy in early breast cancer patients after…
- Trial name
- NCT06375798
- Testing
- radiotherapy
- Where
- China
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University Fourth Hospital
Chronic Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study
This is a prospective single-center cohort study conducted at The First Affiliated Hospital of Xinjiang Medical University, aiming to enroll 400 patients with chronic heart failure (including HFrEF, HFmrEF, HFpEF) and 200 healthy…
- Conditions
- Chronic Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
- Trial name
- HF-MultiOmics (NCT07355088)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xinjiang Medical University
Socket Preservation
Alveolar Ridge Preservation Using Acemannan Aloe Vera Versus Natural Socket Healing
The goal of this clinical trial is to evaluate the effectiveness of acemannan aloe vera powder extract in preserving the alveolar ridge following tooth extraction in healthy adult patients.
- Trial name
- NCT07736053
- Testing
- Aloe vera extract, Normal Socket Healing
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alveolar Ridge Preservation
Alveolar Ridge Preservation Procedures
Tooth loss is accompanied by different patterns of bone loss. Up to 50% loss of alveolar crestal bone width will likely occur 1 year after tooth loss, especially in the anterior maxilla.
- Trial name
- NCT05419778
- Testing
- Osteogen plug®, MInerOss®
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Bone Loss, Vertical Alveolar Bone Loss
Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
The purpose of the present research is to evaluate the effect of bioactive glass in bone regeneration immediately following extraction of mandibular and maxillary premolars.The hypothesis of the study assumes that this treatment…
- Conditions
- Bone Loss, Vertical Alveolar Bone Loss, Horizontal Alveolar Bone Loss
- Trial name
- NCT01878084
- Testing
- bioactive glass (sol-gel), empty extraction socket
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block
The aim is to evaluate post extraction hard tissue changes following ridge preservation using partially demineralized dentin block versus L-PRF block in intact socket in the esthetic zone.
- Trial name
- NCT06275490
- Testing
- Partially Demineralized Dentin Block, L-PRF block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Soft Tissue Conditions
A Comparative Clinical Study Between a Collagen Matrix and Collagen Membrane as Wound Protection During Ridge Preservation ARP
Patients in need of extraction of two teeth in combination with alveolar ridge preservation will be invited to participate in intra-subject RCT on ARP. Prior to surgery, a small-field low-dose CBCT is taken.
- Trial name
- ARP (NCT06029322)
- Testing
- Socket seal after alveolar ridge preservation
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Alveolar Ridge Preservation
Hard and Soft Tissue Changes Following Vestibular Socket Preservation Versus Ice Cream Cone Technique for Management of Defective Fresh Extraction Sockets in the Esthetic Zone: A Randomized Clinical Trial
Evaluation of hard and soft tissue changes following vestibular socket preservation versus ice cream cone technique for management of defective fresh extraction sockets in the esthetic zone.
- Trial name
- NCT06435754
- Testing
- Intervention group Vestibular Socket Preservation, Control Group ice cream cone technique
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Socket Preservation
Post Extraction Changes After Ridge Preservation Using Allogeneic Dentin Matrix Vs Demineralized Freeze Dried Allograft
the aim of this study is to establish if there are clinical, radio-graphical and histomorphometrical differences between using Allogenic Demineralized Dentin matrix versus Demineralized Freeze-Dried Bone Allograft (DFDBA) as a…
- Trial name
- NCT06318650
- Testing
- Demineralized Dentin Matrix, Demineralized freeze-dried bone allograft (DFDBA)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase
Clinical Assessment of UV Photofunctionalization on Stability and Osseointegration of Early Loaded Implants
The goal of this clinical trial is to learn if UV light treatment (photo functionalization) works to help dental implants heal faster and become stable enough for early use in adults missing teeth in the lower back jaw.
- Conditions
- Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase, Determining the Feasibility and Success Rate of an Accelerated "Early Loading" Protocol, Assessing the Survival Rate of the Implants, Along With the Peri-implant Soft Tissue Response and Marginal Bone Preservation
- Trial name
- UV (NCT07868744)
- Testing
- UV-photofunctionalized titanium dental implants
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt