Clinical trials: Tobacco, open to volunteers
Smoking, Smoking Behaviors
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible products.
- Conditions
- Smoking, Smoking Behaviors, Nicotine Dependence
- Trial name
- NCT06077240
- Testing
- E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors, E-cigarette with 2.4% Nicotine with Tobacco Flavor Only, E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Yale University
Alcohol Use Disorder (AUD), Nicotine Use Disorder
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Using a randomized controlled trial (RCT), the goal of this study is to evaluate the ability of evidence based behavioral treatment (contingency management: CM) to significantly decrease alcohol use and cigarette smoking among…
- Trial name
- PERRAS (NCT05181891)
- Testing
- Contingency Management, Non-contingent control
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Washington State University
Cigarette Smoking
Effects of Tax Proposals and Cigarette Availability on Tobacco Purchasing
This study will investigate the effects of normal-nicotine versus low-nicotine cigarette availability in the context of four tax proposals (Tobacco Parity, Nicotine-Content, Harm-Reduction, and Modified Risk Tobacco Product-based…
- Trial name
- NCT07142668
- Testing
- Harm Reduction Tax - Normal Nicotine Cigarettes Available, Harm Reduction Tax - Normal Nicotine Cigarettes Not Available, Modified Risk Tobacco Product Tax - Normal Nicotine Cigarettes Available
- Where
- 2 sites in United States
- Volunteers
- 316 people
- Sponsor
- Virginia Polytechnic Institute and State University
Tobacco Use Cessation
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
- Trial name
- PROMOTE-UP (NCT05415761)
- Testing
- iCanQuit, iCanQuit+Motiv8, Florida quit line
- Where
- United States
- Volunteers
- 1,332 people, healthy volunteers welcome
- Sponsor
- University of Florida
Physician's Role, Smoking Cessation
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care…
- Conditions
- Physician's Role, Smoking Cessation, Smoking
- Trial name
- NCT05846841
- Testing
- Precision Treatment, Usual Care
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Washington University School of Medicine
Lung Cancer Screening, Tobacco Use Disorder
Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA…
- Conditions
- Lung Cancer Screening, Tobacco Use Disorder, Smoking Cessation
- Trial name
- NCT07576595
- Testing
- Smoking cessation multilevel Intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Smoking Cessation, Early-Stage Cancer
Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of a Multi-Theory Model (MTM)-based AI agent intervention for smoking cessation in early-stage cancer patients (clinical stage cTNM 0~II) who currently smoke.
- Conditions
- Smoking Cessation, Early-Stage Cancer, AI Agent
- Trial name
- NCT07827066
- Testing
- MTM-Based AI Agent for smoking cessation, Counseling
- Volunteers
- 156 people
- Sponsor
- Sun Yat-sen University
Lung Carcinoma
Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines
This implementation study will examine the best ways to refer heavy smokers to information about lung cancer screening.
- Trial name
- NCT04595422
- Testing
- Educational Intervention, Questionnaire Administration, Survey Administration
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Use Disorder, Nicotine Dependence
Beta-Adrenergic Modulation of Drug Cue Reactivity
This study is designed to investigate the effects of a beta-adrenergic antagonist (Propranolol; 40 mg IR) and nicotine patch (14 mg) administered alone and in combination on neurobiological and behavioral responses to smoking…
- Conditions
- Tobacco Use Disorder, Nicotine Dependence, Cigarette Smoking
- Trial name
- NCT05587361
- Testing
- Propranolol, Nicotine Patch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation, Second Hand Tobacco Smoke
The "Quit-for-Kids" Project: to Increase Abstinence and Protect Children From Tobacco Smoke Exposure
This project aims to test the effectiveness of an integrated intervention of brief cessation advice (AWARD), Nicotine Replacement Therapy, and Instant Messaging support compared with waitlist control participants among adult…
- Trial name
- NCT06127589
- Testing
- Brief cessation advice (AWARD), Nicotine Replacement Therapy (NRT), Instant messaging Support (IM)
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cancer (With or Without Metastasis)
Feasibility Study Incorporating Music Therapy to Optimise the Smoking Cessation Process Coordinated by a Tobacco Addiction Nurse in Smoking Patients Being Treated for Cancer
The innovative nature of this project lies in the combination of three types of intervention: tobacco addiction treatment, music therapy and therapeutic education. Three disciplines that work together. 1.
- Trial name
- TEMPOS (NCT07198971)
- Testing
- Music therapy
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Smoking ( Cigarette), Smoking (Tobacco) Addiction
Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life
Tobacco smoking remains one of the leading preventable causes of disease, disability, and premature death worldwide. According to the World Health Organization, tobacco use is responsible for more than eight million deaths each…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- Wear-Smile (NCT07593742)
- Testing
- Telemedicine-Based Smoking Cessation Program, Conventional Smoking Cessation Behavioral Program
- Volunteers
- 102 people
- Sponsor
- University of Salerno
Peer Recovery Coaching for TUD
Peer Recovery Coaching for Tobacco Abstinence in People With Opioid Use Disorder
Tobacco use is a leading cause of premature death among individuals with opioid use disorder (OUD). Nearly 75% of individuals receiving medication treatment for OUD report concurrent tobacco use disorder (MOUD-TUD), yet…
- Trial name
- PeerTTS (NCT06965153)
- Testing
- Dual NRT, PeerTTS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation, Cigarette Smoking
Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation
This pilot randomized controlled trial will test the feasibility of a smoking cessation intervention using mindful smoking practice and a smartphone-based sensor-band among adults who regularly smoke cigarettes.
- Conditions
- Smoking Cessation, Cigarette Smoking, Tobacco Use, Nicotine Dependence
- Trial name
- NCT07789496
- Testing
- Mindful Smoking and Sensor-Band Intervention, Smoking Cessation Information
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Tobacco Smoking, Harm Reduction
Smoking Harm Reduction Using E-cigarettes and Cytisine
Smoking remains the leading cause of preventable death globally, with high prevalence in disadvantaged populations despite access to free nicotine replacement therapy (NRT) and counseling through Ontario's STOP Program.
- Conditions
- Tobacco Smoking, Harm Reduction, Nicotine
- Trial name
- SHRECC (NCT07274475)
- Testing
- E-cigarette e-liquid, Cytisine
- Volunteers
- 6,000 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking, Cigarette, Regional Anesthesia
Impact of Smoking on Ultrasound-Guided Infraclavicular Brachial Plexus Block Onset and Duration
The present study will be conducted involving 40 patients aged 18-65 years with ASA physical status I and II, scheduled for acute or elective hand or forearm surgery under the lateral infraclavicular block.
- Trial name
- NCT06755229
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Cigarette Smoking-Related Carcinoma
Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance
This study evaluates histories among cannabis and tobacco co-users of their initiation, escalation, and maintenance of the co-use behavior.
- Trial name
- NCT07439471
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Roswell Park Cancer Institute
Tobacco Prevention
Effectiveness of an Online Quiz in Promoting Tobacco-Related Knowledge, Attitudes, and Behaviours Among Primary Students
The goal of this modified pilot RCT is to evaluate the effects of the intervention (online platform) on tobacco-related knowledge, attitudes and intentions on smoking among local primary 5-6 school students.
- Trial name
- NCT06913166
- Testing
- Online quiz competition
- Where
- Hong Kong
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smokeless Tobacco
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects
This study seeks to measure the effects of smokeless tobacco product risk messages on sensory experiences and future intentions to use.
- Trial name
- NCT07107139
- Testing
- Copenhagen group, Snus group
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Chronic Pain, Tobacco Use
Opioids, Low Nicotine Cigarettes, and Chronic Pain
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain…
- Conditions
- Chronic Pain, Tobacco Use, Opioid Substitution Treatment
- Trial name
- NCT06747871
- Testing
- Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University