Clinical trials: Tobacco Consumption
Cigarette Smoking, Smoking Behaviors
Switch or Quit R01
This study evaluates whether non-cigarette tobacco products (e-cigarettes) can help smokers quit smoking as compared to traditional quit methods (nicotine replacement therapy or varenicline/Chantix).
- Trial name
- NCT06373679
- Testing
- Switching to E-Cigarette, Switching using Medication
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking, Tobacco Use
Testing Counseling Styles to Motivate Smokers to Quit
The purpose of this study is to determine, among a sample of general adult smokers, the effectiveness of three different counseling interventions for motivating quit attempts among smokers not yet ready to quit.
- Conditions
- Smoking, Tobacco Use, Nicotine Dependence
- Trial name
- NCT01188018
- Testing
- Brief Advice (BA), Motivational Interviewing (MI), Health Education (HE)
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Alcoholism, Nicotine Dependence
Varenicline and Alcohol in Inpatient Addictions Program (IAP)
The overall hypothesis of this line of research is that varenicline will decrease alcohol consumption and tobacco use and will increase alcohol and tobacco abstinence rates.
- Trial name
- NCT01169610
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Smoking &Amp; Tobacco Cessation
Community-based Mobile-assisted Brief Intervention for Smoking Cessation
The goal of this pilot trial is to evaluate the feasibility of a mobile-assisted brief intervention for smoking cessation in community-based individuals in Singapore. Specific aims include: 1.
- Trial name
- NCT07375459
- Testing
- Brief cessation advice + self-help booklet, Opt-out referral, Mobile chat messaging
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Nicotine Dependence, Cigarettes
Negotiating a Quit Date or Not in Online Interventions
The primary purpose of the current study is to test the effect of providing users of automated web-based smoking cessation interventions with the option of negotiating and re-negotiating the quit date.
- Trial name
- NCT03194919
- Testing
- Endre: a digital smoking cessation counsellor
- Where
- 2 sites in Czechia, Norway
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Nicotine Dependence, Tobacco Dependence
Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia
This proposal tests the efficacy of a phone-based tobacco cessation intervention for people living with HIV (PLWH) in comparison to the standard of care (brief advice to quit) and nicotine replacement therapy (nicotine patches)…
- Trial name
- Quit4Life (NCT05487807)
- Testing
- Nicotine patch, text messaging
- Where
- 2 sites in Uganda, Zambia
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cannabis Use Disorder, Tobacco Use Disorder
Clinical Trial Tobacco Marijuana
Approximately 50% of persons seeking treatment for cannabis-use disorders (CUDs) regularly smoke tobacco. Combining tobacco with cannabis has become a common method of smoking cannabis.
- Trial name
- RCTTM (NCT02277665)
- Testing
- CUD Treatment, Tobacco Treatment
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
HIV, Smoking
Reduce Tobacco Use in People Living With HIV in Switzerland
The purpose of this trial is to test the effectiveness of offering a menu of different tobacco smoking substitutional products (e-cigarettes, nicotine pouches, nicotine patches in addition to usual of care) for smokers in the…
- Trial name
- RETUNE (NCT06789692)
- Testing
- tobacco smoking substitution products
- Where
- 7 sites in Switzerland
- Volunteers
- 972 people
- Sponsor
- University Hospital, Basel, Switzerland
Tobacco Use Disorder, Cigarette Smoking
Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers
The purpose of the study is to compare two different dosage forms from which nicotine is released and absorbed into the bloodstream.
- Trial name
- NCT02906995
- Testing
- Sublingual tablet 4 mg versus Nicorette Lozenge 4mg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Smoking Status
Evaluation of Adolescent Smoking Cessation Programs
The purpose of this study was to determine if a school-based multi-session group smoking cessation program is more effective than a single session group program.
- Trial name
- NCT00714207
- Testing
- NOT program, NOT controls, Kicking Butts intervention
- Where
- 8 sites in United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pregnancy
Prenatal Exposure Effects Psychophysiology Study
The purpose of the study is to understand the biology and behavior of early mother-infant attachment, and to investigate how it may be affected by prenatal substance exposures.
- Trial name
- PEEPS (NCT01134770)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tobacco Use Cessation
Tobacco Quitlines:Adjunct to Dental Office Tobacco Intervention
The purpose of the study is to compare two methods for providing brief dental office-based interventions designed to help patients quit either cigarette smoking or smokeless tobacco use, and to compare these two dental…
- Trial name
- NCT00384254
- Testing
- 5 A, 3 A
- Where
- United States
- Volunteers
- 2,177 people
- Sponsor
- Oregon Research Institute
Tobacco Use, Tobacco Smoking
Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]
To pilot test the appeal of non-tobacco oral nicotine products in cigarette smokers, smokeless tobacco users, and oral nicotine users.
- Conditions
- Tobacco Use, Tobacco Smoking, Cigarette Smoking, Smokeless Tobacco Cessation
- Trial name
- NCT05030194
- Testing
- Electronic Cigarette, Oral Nicotine Pouch
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Healthy Subject
Text Messages in Preventing Tobacco Use in Young Adults
This trial studies how well text messages work in preventing tobacco use in young adults. Text messaging may help to teach young adults about the risks of tobacco products.
- Trial name
- NCT03457480
- Testing
- Computer-Assisted Intervention, Focus Group, Informational Intervention
- Where
- United States
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking, Nicotine Addiction
STOP Study: Effectiveness of Zyban in a Clinical Population
Despite the significant health, social and economic costs of cigarette smoking, 17% of Ontarians still currently smoke. Use of smoking cessation pharmacotherapy such as Zyban (bupropion HCl) has been shown to double quit rates…
- Conditions
- Cigarette Smoking, Nicotine Addiction, Smoking Cessation
- Trial name
- NCT01015170
- Testing
- bupropion HCl
- Where
- 24 sites in Canada
- Volunteers
- 454 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Dependence, Smoking Cessation
Tailoring Varenicline to Individual Needs (TVIN Study)
Varenicline is a partial nicotinic agonist which acts on alpha4 beta2 nicotinic receptors. It is presumed to alleviate withdrawal discomfort, but also to diminish rewarding effects of cigarettes.
- Trial name
- TVIN (NCT01206010)
- Testing
- Varenicline
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Nicotine Dependence, Tobacco Use Disorder
A Survey on Consumer Use of Over-the-Counter (OTC) Nicotine Patches
Since 1996, the nicotine patch has been re-classified from prescription to over-the-counter (OTC) status in the United States. Little is known about how the public uses the OTC nicotine patch due to lack of monitoring.
- Trial name
- NCT00134927
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Bladder Cancer, Cervical Cancer
Acceptability of Less Harmful Alternatives to Cigarettes
RATIONALE: A study that evaluates participants' beliefs about smokeless tobacco products and nicotine replacement therapy may be useful in helping smokers stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00957424
- Testing
- telephone-based intervention, nicotine replacement therapy, informational intervention
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Roswell Park Cancer Institute
Tobacco Use Disorder
Safety of Combining Modafinil and Nicotine Replacement Therapy in Treating Nicotine Dependent Adolescents
Nicotine is one of the most widely abused substances in the United States. Nicotine replacement therapy (NRT) is currently an effective treatment for nicotine dependence; however, even with NRT most people fail at quitting…
- Trial name
- NCT00258479
- Testing
- ModafinilNicotine Replacement Therapy, Modafinil
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Catherine Martin, MD
Tobacco Dependence
Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1
Schizophrenia is associated with high rates of cigarette smoking and associated morbidity and mortality. In this study, smokers with schizophrenia will complete a baseline session and then randomized to varenicline (VAR) or…
- Trial name
- NCT03507127
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Brown University
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