Clinical trials: Tobacco Consumption
Smoking Cessation, Tobacco Use Cessation
Safety and Effectiveness of NicVAX in Treating Nicotine Dependent Individuals
Nicotine is highly addictive and many individuals are unable to quit smoking even with treatment. The purpose of this study is to determine the effectiveness of various doses of NicVAX in treating nicotine dependent individuals.
- Trial name
- NCT00218413
- Testing
- NicVAX
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Nabi Biopharmaceuticals
Tobacco Dependence
Preventing Tobacco Relapse With Omega-3s Trial
Almost 12% of women report smoking during pregnancy. Smoking during pregnancy is associated with adverse fetal outcomes and up to 35-75% of women quit smoking during their pregnancy.
- Trial name
- PRO-3 (NCT03113370)
- Testing
- Fish Oil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Alcohol Dependence, Nicotine Dependence
New Treatment for Alcohol and Nicotine Dependence
This research study aims to test whether topiramate (a drug that is being used for seizure) will help individuals who have problems with both alcohol and nicotine.
- Trial name
- NCT01182766
- Testing
- Low-Dose Topiramate, High-Dose Topiramate
- Where
- 4 sites in United States
- Volunteers
- 236 people
- Sponsor
- University of Virginia
Electronic Cigarette Use, Smoking, Cigarette
Assessing E-Cigarettes for Tobacco Harm Reduction in the Context of Lung Cancer Screening
This study investigates the feasibility, acceptability, and short-term effects of providing 4 weeks of complimentary electronic cigarettes (ECs) to 30 individuals who did not quit after smoking cessation treatment provided in the…
- Conditions
- Electronic Cigarette Use, Smoking, Cigarette, Nicotine Dependence
- Trial name
- NCT06472869
- Testing
- NJOY ACE e-cigarette
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Tobacco Dependence
Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches
To test if smokeless tobacco is more effective than nicotine buccal tablets in smoking cessation compared with a control group with low dose nicotine patches.
- Trial name
- NCT00313105
- Testing
- Smokeless tobacco (Oliver Twist pellets), smoking cessation counseling
- Where
- Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Cigarette Smoking
Mobile App Based Personalized Solutions and Tools for Medication Adherence of Rx Pills
The primary aim of this study is to conduct a 9-patient feasibility and acceptability study of mSMART (with future studies focusing on improved medication adherence).
- Trial name
- mSMART (NCT02072005)
- Testing
- mSMART smartphone application
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
Cigarette Smoking, Obesity
Pre to Postoperative Smoking Cessation
The study will evaluate the feasibility of integrating an intensive pre- post-surgical smoking cessation intervention into a hospital setting, and assess measures of postsurgical recovery as a function of smoking cessation status.
- Trial name
- NCT02683161
- Testing
- Varenicline, Contingency Management, Behavioral Counseling
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Cigarette Smoking
Contingency Management for Smoking Cessation in Pregnant Minority Women
The long-term goal of this research is to reduce tobacco-related disparities in maternal and infant health outcomes by improving smoking cessation and relapse prevention interventions for minority pregnant and postpartum women…
- Trial name
- NCT02195570
- Testing
- Quit Smoking Now (QSN), Prize-based Contingency Management (CM)
- Where
- United States
- Sponsor
- University of Miami
THC, Cannabis
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering cannabis and tobacco.
- Conditions
- THC, Cannabis, Cannabis Use, Cannabis Smoking
- Trial name
- CANNIC (NCT05999383)
- Testing
- Cannabis, Nicotine, Pax Loose Leaf Vaporizer
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence
Smoking Treatment and Anxiety Management Program
The Smoking Treatment and Anxiety Management Program (STAMP) is a treatment program focused on helping people manage their anxiety while quitting smoking.
- Trial name
- STAMP (NCT01753141)
- Testing
- Cognitive Behavioral Therapy for smoking cessation, Cognitive Behavioral Therapy for smoking cessation and anxiety sensitivity reduction.
- Where
- United States
- Volunteers
- 378 people
- Sponsor
- Florida State University
Tobacco Use, Parental Smoking
An Intervention to Address Parental Smoking During the Postpartum Hospitalization.
The purpose of the study is to find better ways to help parents quit smoking, thus improving their own health, the health of their children, and the health of other family members.
- Trial name
- NEWS (NCT00844818)
- Testing
- Telephone Quitline Enrollment
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Massachusetts General Hospital
Tobacco Use Disorder, HIV
RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers
This trial will compare the efficacy of Positively Smoke Free on the Web+ (a smoking cessation program + social network for HIV-infected smokers) to the American Heart Association Getting Healthy website in promoting abstinence…
- Trial name
- PSFW+ (NCT02781090)
- Testing
- PSFW+, AHA, Nicotine polacrilex
- Where
- 2 sites in United States
- Volunteers
- 512 people
- Sponsor
- Montefiore Medical Center
Cigarette Smoking
Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers
The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking
- Trial name
- NCT00843622
- Testing
- Low-nitrosamine smokefree tobacco product for oral use
- Where
- 4 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB
Electronic Cigarette Use, Cigarette Use, Electronic
Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1
This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco…
- Conditions
- Electronic Cigarette Use, Cigarette Use, Electronic, Vaping, Cigarette Smoking
- Trial name
- NCT04399031
- Testing
- E-cigarette e-liquid
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cigarette Smoking, Smoking Behaviors
A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse
This is a research study to find out if treatment decision making can be improved for smokers who find it difficult to quit with medications.
- Conditions
- Cigarette Smoking, Smoking Behaviors, Treatment
- Trial name
- ADAPT (NCT06118502)
- Testing
- Switching to a different medication, Continued use of the same medication, Switching to a harm reduction tobacco product
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Tobacco Use Cessation
Interactive Communication Technologies and Nicotine Replacement Therapy Sampling for Smokers
Brief advice combined with active referral to smoking cessation (SC) services increases quitting. We aim to strengthen the effect of combined intervention by using interactive communication technologies and nicotine replacement…
- Trial name
- NCT04001972
- Testing
- Brief advice (AWARD model), NRT-S, IM Apps and Chatbot
- Where
- Hong Kong
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking, Smoking, Cigarette
Tabata Exercise on Nitric Oxide Synthases and Maresin
Smoking causes chronic inflammation and endothelial dysfunction through alterations in nitric oxide synthase (NOS) pathways. Maresin is an anti-inflammatory pro-resolving lipid mediator that plays important roles in the…
- Trial name
- NCT07412639
- Testing
- Tabata Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Nicotine Dependence, Cigarettes
Improving Smoking Cessation in Socioeconomically-Disadvantaged Young Adults
The purpose of this study is to understand how to develop and deliver a better smoking cessation program for lower-income young adult smokers.
- Trial name
- NCT04379388
- Testing
- Web + text smoking cessation intervention
- Where
- United States
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco Use Disorder
Computer-Assisted Stop-Smoking Program in Helping Doctors Counsel Patients Who Smoke Cigarettes
RATIONALE: A computer-assisted stop-smoking program may help doctors counsel patients who smoke and may help increase the number of patients who stop smoking.
- Trial name
- NCT00865553
- Testing
- computer-assisted smoking cessation intervention, cancer prevention, educational intervention
- Where
- United States
- Volunteers
- 630 people
- Sponsor
- University of Vermont
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