Clinical trials: Tobacco Smoking
Smoking Cessation
Exploratory Study of Switching From Combustible Cigarettes to the BIDI E-cigarette
The aim of this study is to shed light on the importance of nicotine pharmacokinetics in switching to a reduced-harm product by fully matching the nicotine pharmacokinetics of smokers' usual brands of cigarettes.
- Trial name
- NCT05855343
- Testing
- BIDI Stick e-cigarette
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Nicotine Dependence, Electronic Cigarette Use
Methadone-Maintained Smokers Switching to E-Cigarettes
Participants in this randomized clinical trial will be methadone-maintained smokers interested in switching to electronic cigarettes (ECs).
- Trial name
- SHINE (NCT05206435)
- Testing
- Electronic Cigarette, Nicotine Lozenge
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Butler Hospital
Nicotine Dependence, Schizophrenia
Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia
Background: Some people with schizophrenia have problems with their working memory and paying attention for extended periods. These difficulties cannot be treated with antipsychotic medications or with many standard therapies.
- Trial name
- NCT01034085
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers
Pilot randomized controlled trial evaluating feasibility, acceptability, and trial-readiness of the new app compared with the existing print booklets and the NCI SmokefreeTXT en Español program.
- Trial name
- NCT07754448
- Testing
- Libre del Cigarrillo Smartphone App, Libre del Cigarrillo Printed Booklets, SmokefreeTXT en Español
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Nicotine Dependence
Smoking Treatment and Anxiety Management Program
The Smoking Treatment and Anxiety Management Program (STAMP) is a treatment program focused on helping people manage their anxiety while quitting smoking.
- Trial name
- STAMP (NCT01753141)
- Testing
- Cognitive Behavioral Therapy for smoking cessation, Cognitive Behavioral Therapy for smoking cessation and anxiety sensitivity reduction.
- Where
- United States
- Volunteers
- 378 people
- Sponsor
- Florida State University
Smoking Cessation
Pharmacoeconomic Assessment in Nabi-4514 and Nabi-4515 Phase 3 Studies
The purpose of this study is to look at pharmacoeconomic data for subjects that have received either NicVAX or placebo in the Nabi-4514 or Nabi-4515 studies.
- Trial name
- NCT01178346
- Testing
- NicVAX vaccine
- Where
- 25 sites in United States
- Volunteers
- 500 people
- Sponsor
- Nabi Biopharmaceuticals
Periodontitis, Smoking
Relationships Between Tenascin C, Smoking and Periodontal Status
The goal of this observational study is to determine if there is a relationship between different periodontal conditions (gingival healthy, stage 2 grade B, stage 2 grade C, stage 3 grade B, stage 3 grade C) and the levels of…
- Conditions
- Periodontitis, Smoking, Periodontal Diseases
- Trial name
- NCT06523205
- Testing
- Clinical Measurements and Saliva Sample Collection
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Smoking Cessation
Efficacy of Brief MI Delivered Via Mobile Instant Messaging to Help Unmotivated Smokers With Chronic Diseases to Quit
This study aims to examine the efficacy of brief MI delivered by mobile instant messaging tools in promoting smoking cessation among unmotivated smokers with chronic diseases.
- Trial name
- NCT04890223
- Testing
- Brief MI intervention
- Where
- Hong Kong
- Volunteers
- 728 people
- Sponsor
- The University of Hong Kong
Smoking Cessation
Building Capacity and Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2018
The present study will examine (1) the effectiveness of a combined intervention of face-to-face brief cessation advice (AWARD), active referral of SC service plus financial incentive on encouraging SC services use and (2) explore…
- Trial name
- NCT03565796
- Testing
- Personalized active referral plus financial incentive, AWARD advice, Warning leaflet
- Where
- China
- Volunteers
- 1,093 people
- Sponsor
- The University of Hong Kong
Cerebrovascular Disorders, Smoking Cessation
Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease
Research Aims The aims of this research study are to determine whether cost-free smoking cessation pharmacotherapy: 1. Helps smokers with Transient Ischemic Attack (TIA) or stroke to quit smoking over the long-term, compared to…
- Trial name
- NCT00962988
- Testing
- Cost-Free Pharmacotherapy Group, Prescription Only Group
- Where
- 2 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Tobacco Smoking
Behavioral Interventions to Target Self-Control
Low self-control has been associated with a number of unhealthy behaviors with low treatment success. Alternative non-pharmacological approaches have the potential for enhancing self-control.
- Trial name
- NCT02281942
- Testing
- Yoga, Education
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Smoking Cessation
Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Students
The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 120 student smokers (18 to 25 years old).
- Trial name
- NCT05589220
- Testing
- Music Intervention, Nicotine replacement
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Poitiers University Hospital
Smoking
Very-Low Nicotine Cigarettes and Non-Daily Smokers
The purpose of this research study is to investigate the impact of different nicotine levels in cigarettes among non-daily smokers.
- Trial name
- NCT02228824
- Testing
- Very low nicotine content cigarettes, Normal nicotine content cigarettes
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Saul Shiffman
Tobacco Smoking Behavior
Switching to Reduced Oxidant or Nicotine Content Cigarettes in Smokers
The overall objectives of this clinical study are to determine in smokers the short term effects of switching to tobacco products that deliver low levels of nicotine or reactive oxygen/nitrogen species (ROS/RNS) on smoking…
- Trial name
- NCT02415270
- Testing
- Reduced Nicotine Cigarettes, Reduced ROS/RNS, Control
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Heavy Smoking
Bronchoscopy Screening for High-risk Population of Lung Cancer With Severe Smoking With Negative LDCT Screen
Based on the previous work of LDCT screening, in order to improve the screening rate of central lung cancer for LDCT negative and severe smokers, the investigators plan to conduct China's first large-scale fluorescent…
- Trial name
- NCT04413669
- Testing
- white light bronchoscopy & autofluorescence bronchoscopy
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jiayuan Sun
Smoking, Cancer
Self-determination Plus Instant Messaging for Smokers With Cancer
Objective: To test the efficacy of a self-determination theory-based intervention plus instant messaging to help smokers with cancer quit smoking.
- Trial name
- NCT05643469
- Testing
- Self-determination theory-based intervention plus instant messaging, AWARD model
- Where
- Hong Kong
- Volunteers
- 1,448 people
- Sponsor
- Chinese University of Hong Kong
Smoking ( Cigarette), Women
Smoking, Pain Threshold, and Hand Strength in Women
This study aims to investigate the effects of smoking on pain threshold, cervical position sense, and grip strength in women. Measurements will include pressure pain threshold (PPT), cervical position sense (CPS), grip strength…
- Conditions
- Smoking ( Cigarette), Women, Pain
- Trial name
- NCT07611760
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Karabuk University
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Smoking Cessation
Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions
The research study, "Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions" will test two smoker-driven, social marketing innovations to recruit and engage smokers in Decide2Quit.org…
- Trial name
- NCT03224520
- Testing
- Recommender CTHC, Standard CTHC, Peer Recruitment
- Where
- United States
- Volunteers
- 1,487 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Healthy Subject
A Smoking Prevention Program (ASPIRE) and Mentoring for Preventing Smoking Among High School Youths
This early phase I trial studies how well A Smoking Prevention Interactive Experience (ASPIRE) program and mentorship works in preventing smoking in high school students.
- Trial name
- NCT04803682
- Testing
- Preventive Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
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