Clinical trials: Tobacco Smoking
Smoking Cessation
Personalized Smoking Cessation Tool Based on Patient Lung CT Image
Imbio is developing a Smoking Cessation Report (Report) that includes data analysis from a CT lung cancer screening exam. This randomized controlled (RCT) trial will clinically validate the Report's effectiveness at motivating…
- Trial name
- NCT03087617
- Testing
- Imbio Smoking Cessation Report, Smoking Cessation Counseling, Usual Care
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- Imbio
Alcohol Drinking, Cigarette Smoking Toxicity
Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder
The proposed research will investigate whether smokers with vs. without current at-risk alcohol drinking (ARD) respond to reduced nicotine cigarettes by increasing their alcohol consumption or smoke exposure, thereby diminishing…
- Trial name
- RedNic (NCT02990455)
- Testing
- Reduced nicotine cigarettes
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Battelle Memorial Institute
Cigarette Smoking
Neurobehavioral Substrates of Propranolol's Effects on Drug Cue Reactivity
The central objective of this project is to obtain proof-of-concept data demonstrating the effects of propranolol (a beta-adrenergic antagonist) on neurobiological responses to personal smoking environments and behavioral…
- Trial name
- ProCue (NCT03309943)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Cigarette Smoking, Vaping
Menthol and Mint Experimental Tobacco Marketplace (ETM) Study
Menthol cigarettes comprise almost one-third of the United States (US) market share and are disproportionately smoked by racial minorities.
- Trial name
- NCT04879225
- Testing
- Tobacco e-liquids, Menthol and Tobacco e-liquids, Mint, Menthol and Tobacco e-liquids
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Smoking Cessation
Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion)
This research focuses on maximizing the benefits of proven smoking cessation interventions to support people who smoke to quit, as part of the strategy to help New Zealand become smoke-free.
- Trial name
- Cess@Tion (NCT05311085)
- Testing
- Cytisine, Nicotine delivered via an e-cigarette, Cytisine plus nicotine delivered via an e-cigarette
- Where
- New Zealand
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Smoking Cessation
Effects of a Smoking Cessation Program for Prison Inmates
According to WHO database, an average of 540 million people worldwide dies from smoking related diseases every year. The use of tobacco products may reduce the average life expectancy of about 15 years.
- Trial name
- NCT01417793
- Testing
- Smoking Cessation Program
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Pregnancy, Smoking
Self-Monitoring of Carbon Monoxide to Enhance Reproductive Outcomes in Women
Our goal is to study self-monitoring of smoking as a means to reduce smoking in pregnant women. Investigators hypothesize that more regular self-monitoring, text messages and feedback as provided by home carbon monoxide…
- Conditions
- Pregnancy, Smoking, Smoking Cessation
- Trial name
- NCT02246114
- Testing
- piCO+ Smokerlyzer® monitor, Text messages
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hypertension, Type 2 Diabetes
Project WHADE: A Partner-Based Physical Activity Program for Women
This study is designed to test the feasibility and acceptability of a new method for supporting physical activity among women ages 40-65 who have risk factors for cardiovascular disease.
- Conditions
- Hypertension, Type 2 Diabetes, Metabolic Syndrome, Smoking
- Trial name
- NCT06350604
- Testing
- Project WHADE: A Partner-Based Physical Activity Program for Women
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Rowan University
Coronary Artery Disease
The Influence of Smoking Status on Prasugrel and Clopidogrel Treated Subjects Taking Aspirin and Having Stable Coronary Artery Disease
This study is being conducted to determine if smoking will influence the platelet aggregation inhibition ability of clopidogrel and prasugrel.
- Trial name
- NCT01260584
- Testing
- Prasugrel, Clopidogrel
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- Daiichi Sankyo
Covid19, Smoking
The Effects of Smoking on Mortality in Patients With Acute Respiratory Syndrome Coronavirus 2 Infection
This is a retrospective single centered study that was done in the ICU on patients with Covid-19 between 16th of March -16th of May in 2020 Retrospective records will be examined by examining the electronic data files of the…
- Trial name
- NCT04874363
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Smoking Cessation Programme in Workplaces in Hong Kong (Phase IV)
Smoking causes cardiovascular and respiratory diseases, cancers and diabetes, and it has been a leading risk factor for death globally.
- Trial name
- NCT03870906
- Testing
- Occupational-specific health talk, WhatsApp interaction, Phone follow-up/counselling service
- Where
- Hong Kong
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation
Smoking Among Resident Physician and Their Role in Smoking Cessation Advice
smoking is a key modifiable risk factor that greatly increases the likelihood of 2 dying young from cancer, heart disease, and lung disorders The World Health Organization (WHO) reports that 3 tobacco products are used by…
- Trial name
- NCT07075263
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 225 people
- Sponsor
- Mansoura University Hospital
Nicotine Dependence
Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction
Background: Treatment for nicotine addiction is characterized by high rates of relapse. New treatment therapies for nicotine addiction are exploring the use of brain scanning equipment to control and decrease nicotine and…
- Trial name
- NCT01031693
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Implementation of Smoking Cessation Within NCI Community Oncology Research Program (NCORP) Sites
Evaluate a multi-faceted training program to improve short-term smoking cessation rates (<14 days post-visit) and short (3 months) and sustained abstinence (6 months) among 1,114 enrolled smokers who present for low-dose computed…
- Trial name
- OaSiS (NCT03291587)
- Testing
- Personnel Training and Coaching Calls
- Where
- 49 sites in United States
- Volunteers
- 1,094 people
- Sponsor
- Wake Forest University Health Sciences
Alcohol Reactivity
Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
The purpose of this study is the examine the effect of varenicline on cognition to a high dose (0.08 g/dL) of alcohol (vs. placebo alcohol) over the ascending and descending limb of the blood alcohol curve.
- Trial name
- NCT01000987
- Testing
- varenicline
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Quitting Smoking, Smoking Cessation
BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study
The purpose of this research study is to see if offering adult primary care patients who smoke combustible cigarettes more frequent outreach, more choices about how they receive that outreach, and more smoking treatment options…
- Conditions
- Quitting Smoking, Smoking Cessation, Smoking, Cigarette
- Trial name
- NCT05683821
- Testing
- Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral
- Where
- United States
- Volunteers
- 12,376 people
- Sponsor
- University of Wisconsin, Madison
Periodontal Disease, Diabete Mellitus
Oral Health and Systemic Diseases: Survey of General Practitioners
This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic…
- Trial name
- NCT07604493
- Testing
- Questionnaire Survey
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Tobacco Dependence
EFFECTIVENESS OF VOLITIONAL HELP SHEETS AS AN ADJUNCT TO TREATMENT TO PROMOTE BEHAVIOR CHANGE: A PILOT STUDY ON SMOKING
Smoking is a major public health concern associated with substantial morbidity and premature mortality. Planning may help people who wish to change their smoking behavior by translating their intentions into action.
- Trial name
- VHS_T (NCT07910214)
- Testing
- Smoking-Specific Volitional Help Sheet
- Where
- France
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Clinique de la Mitterie
Healthy Subject
A Smoking Prevention Program (ASPIRE) and Mentoring for Preventing Smoking Among High School Youths
This early phase I trial studies how well A Smoking Prevention Interactive Experience (ASPIRE) program and mentorship works in preventing smoking in high school students.
- Trial name
- NCT04803682
- Testing
- Preventive Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
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