Clinical trials: Tobacco Smoking
Smoking
Bayesian Neurobehavioral Phenotyping: From Mechanism Identification to Personalized Neuromodulation Treatments. R61 PHASE
The goal of this clinical research study is to learn more about whether individual differences in brain responses to emotional triggers impact rTMS (repetitive transcranial magnetic stimulation) responses in people who smoke.
- Trial name
- NCT06991062
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Depressive Disorder, Smoking
Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers
This study will assess whether varenicline (chantix) has antidepressant properties when used in addition to other psychiatric medication. It will also assess whether varenicline improves the inability to feel pleasure (i.e.
- Trial name
- NCT00525837
- Testing
- fixed dose varenicline, varenicline
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Butler Hospital
Tobacco Smoking
Potential Impact of Menthol Ban in Cigarettes and E-cigarettes
Menthol cigarette use remains a major public health problem and the FDA has proposed to ban menthol in cigarettes. However, additional evidence is needed to understand whether menthol flavor in e-cigarettes is important for harm…
- Trial name
- NCT05259566
- Testing
- menthol ban in cigarettes only, total menthol ban
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Yale University
Nicotine Dependence
Pexacerfont to Reduce Stress-induced Tobacco Craving
Background: Stressful situations often cause tobacco cravings. These cravings can make it very difficult for smokers who are trying to quit. Research has shown that craving may involve hormone pathways in the brain.
- Trial name
- NCT01557556
- Sponsor
- National Institute on Drug Abuse (NIDA)
Passive Smoking
An Intervention to Protect Young Children From Tobacco Smoke Exposure
The primary goal of this research is to evaluate the effectiveness of an intervention for parents to reduce tobacco smoke exposure of young children
- Trial name
- NCT02867241
- Testing
- Behavioral Early, Behavioral Late
- Where
- Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laura J. Rosen
Tobacco Use, Opioid Use Disorder
E-cigarette Switching Older Adults
The goal of this clinical trial is to learn if adults 50 years and older who currently smoke tobacco and are in treatment for opioid use disorder will switch to using e-cigarettes instead of continued smoking.
- Conditions
- Tobacco Use, Opioid Use Disorder, Tobacco-Related Disorders
- Trial name
- NCT06534905
- Testing
- E-cigarette, Control/Standard Advice
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Smoking, Periodontitis
Smoking Dependence and Periodontitis
The present study was designed as a, single-center, prospective cohort study focusing on the relationship between smoking status and the severity of periodontitis
- Trial name
- NCT03901066
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Liege
Smoking
Behavioral Maintenance Treatment for Smoking Cessation
Our primary goal is to examine the effectiveness of a multi-factor maintenance treatment strategy in promoting longer-term smoking abstinence.
- Trial name
- NCT01615770
- Testing
- cognitive behavior therapy
- Where
- 2 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cancer, Smoking Cessation
VIDeOS for Smoking Cessation
The purpose of the current study is to pilot the efficacy, feasibility, and acceptability of an evidence-based smoking cessation intervention adapted for cancer patients and delivered via video.
- Trial name
- NCT06307496
- Testing
- Smoking cessation intervention, Informational intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Nicotine Dependence
Brain Activity and Smoking Cessation
In the current study, the investigators propose to test: (1) whether brain activation and connectivity in a resting state, assessed by ASL perfusion MRI, BOLD fMRI, and diffusion tensor imaging (DTI) predicts smoking relapse, and…
- Trial name
- NCT01186055
- Testing
- Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Rehabilitation; Tobacco Use
Pulmonary Rehabilitation and Smoking
Pulmonary rehabilitation (PR) is known to reduce dyspnea, increase exercise capacity, reduce psychological symptoms and improve quality of life in COPD patients. Some patients continue to smoke despite their illness.
- Trial name
- NCT03671187
- Testing
- Exercise
- Volunteers
- 31 people
- Sponsor
- Izmir Katip Celebi University
Age-related Macular Degeneration, Age-related Maculopathy
GARM II: A Study on the Genetics of Age-related Maculopathy
The original study (GARM I) has been conducted for more than 18 years at the University of Pittsburgh Medical Center (UPMC). GARM II is a nationwide research study about age-related macular degeneration in the next generation of…
- Trial name
- NCT01115387
- Testing
- Observational-1, Observational-2
- Where
- 2 sites in United States
- Volunteers
- 603 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Smoking Abstinence
Effects of AFQ056 and Nicotine in Reducing Cigarette Smoking
The purpose of this study is to assess the safety and efficacy of AFQ056 and nicotine compared to placebo on craving and withdrawal symptoms during voluntary smoking stoppage in healthy smokers.
- Trial name
- NCT00414752
- Testing
- AFQ065
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novartis
Smoking Cessation, Smoking
Smoking Habits and Smoking Cessation in Young Adults
The purpose of this study is to assess the efficacy and effectiveness of varenicline and nicotine patch combined with motivational interview technique in smoking cessation of young adults over 12 months follow-up.
- Conditions
- Smoking Cessation, Smoking, Habits
- Trial name
- NCT01531049
- Testing
- varenicline, Nicotine cutaneous patch 15mg/16h, Nicotine cutaneous patch 10mg/16h
- Where
- Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tuula Toljamo
Lung Cancer
Clinical Trial of Lung Cancer Chemoprevention With Sulforaphane in Former Smokers
This research study involves taking an experimental anti-cancer dietary supplement called Sulforaphane (SF) or a placebo (product without any supplement content) over a period of twelve months in order to determine if it is a…
- Trial name
- NCT03232138
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Jian-Min Yuan, MD
Nicotine Addiction
Developing Evidence to Inform Regulatory Policy on Nicotine Content in E-Liquids
The goal of this observational study is to learn if electronic cigarette users who currently choose to use lower nicotine eliquids have reduced harm compared those who choose higher nicotine eliquids.
- Trial name
- NCT06619964
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rochester Institute of Technology
HIV Positive, Marijuana Smoking
Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients.
- Trial name
- MMC-1 (NCT01536899)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University
Therapeutic Equivalency
Fasting Bioequivalence Study of Pravastatin Sodium 80 mg Tablets Versus Pravachol® 80 mg Tablets In Normal Healthy Subjects
The objective of this study was to compare the rate and extent of absorption of pravastatin sodium from a test formulation of Pravastatin Sodium 80 mg Tablets versus the reference Pravachol® 80 mg Tablets under fasting…
- Trial name
- NCT00650221
- Testing
- Pravastatin
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Tobacco Use Disorder, Smoking Cessation
Mechanisms of Lorcaserin for Smoking Cessation
Identifying new medication options is critical for curbing the health burdens of cigarette smoking. Currently approved smoking cessation medications act on nicotinic receptors, and additional work is needed to identify…
- Trial name
- NCT04396834
- Testing
- Lorcaserin Oral Tablet
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Smoking
Smoking: Cytokines in Vitreous and Aqueous Humor
Smoking is a risk factor for ophthalmologic diseases. Inflammation might play a role in their pathogenesis. This study elucidates intraocular cytokine profiles in smokers and non smokers.
- Trial name
- NCT04178499
- Testing
- cytokine analysis
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
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