Clinical trials: Tooth Caries
Caries,Dental
The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine
Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration
- Trial name
- NCT04303767
- Testing
- Casein phosphopeptide amorphous calcium phosphate, Atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Dental Pulp Capping, Dental Caries Extending to Pulp
Long-term Evaluation of Direct Pulp Capping
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study.
- Trial name
- NCT03403985
- Testing
- Calcium Hydroxide (Ca(OH)2), Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Destructed Teeth Restored by Zirconia Crowns, Zirconia Crowns
Clinical Outcomes of Bonded Monolithic Translucent Zirconia Crowns Using Two Different Compositions of Self-adhesive Resin Cements
The aim of the present study is to evaluate the clinical outcomes (marginal discoloration, marginal adaptation, gingival health, debonding and patient satisfaction) of translucent zirconia crowns bonded by TheraCem (MDP, calcium…
- Conditions
- Destructed Teeth Restored by Zirconia Crowns, Zirconia Crowns, Decayed, Missing, and Filled Teeth, Tooth Discoloration
- Trial name
- NCT04875468
- Testing
- TheraCem self-adhesive resin cement, Multilink adhesive resin cement
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Diana Mostafa Habeb
Dental Caries, Class I Dental Caries
Effect of Surface Sealant Application on Clinical Performance Occlusal Restorations
The aim was to evaluate the clinical performance of HEMA-containing and HEMA-free all-in-one self-etch adhesives with and without a surface sealing process with a nanohybrid composite in occlusal caries restorations.
- Conditions
- Dental Caries, Class I Dental Caries, Dental Composite
- Trial name
- NCT03184025
- Testing
- dentin adhesive
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Dental Caries
SEALANT-DK: Longevity and Efficacy of 6 Resin Sealants Used for Sealing Permanent Teeth in Children and Adolescents
Background: Occlusal caries is the main reason for restorative therapy in the young permanent dentition, but restorations have limited survival time and may also weaken the tooth.
- Trial name
- SEALANT-DK (NCT02561689)
- Testing
- Fissure sealing
- Where
- Denmark
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
The Tayside Brushing Study - Adult Follow up
Historically dental health of Scottish children had been poor for many years. Evidence form clinical trials of fluoride toothpaste identified a route to improving prevention.
- Trial name
- NCT02623283
- Testing
- No intervention given
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NHS Tayside
Dental Caries
Early Childhood Caries Prevention at a Pediatric Clinic
This purpose of this study was to evaluate effectiveness of a risk-based dental caries prevention program conducted by dental personnel at an urban pediatric primary care clinic serving largely low-income residents of Baltimore…
- Trial name
- NCT00497029
- Testing
- fluoride varnish, patient education
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Tooth Crown Fracture, Dental Caries
Clinical Performance of Ceramic CAD/CAM Crowns
The purpose of this study was to evaluate the clinical performance of laboratory and chairside fabricated monolithic anterior and posterior LDGC CAD/CAM crowns performed by predoctoral students at the University of Toronto and…
- Trial name
- NCT03921307
- Where
- Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dental Caries
Clinical Performance of a Glass-ionomer Restorative System: A 6-year Evaluation
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in class I and class II cavities.
- Trial name
- NCT02888912
- Testing
- EQUIA, Gradia Direct Posterior
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries,Dental
Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101
Pharmacokinetic (PK) study of L-arginine after exaggerated oral use of the novel dentifrice product COL101 after repeated daily applications in healthy adult subjects.
- Trial name
- NCT06182267
- Testing
- L Arginine, Sodium Fluoride
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Root Caries
Effectiveness on SDF Solution and PVP-I Combined NaF Varnish in Preventing Root Caries in Elders
The main objective of this study is to compare the effectiveness and cost-effectiveness of 4-monthly application of 10% povidone iodine solution followed by 5% sodium fluoride varnish with those of annual application of 38%…
- Trial name
- NCT03654820
- Testing
- PVP-I solution combined with NaF varnish, SDF solution
- Where
- China
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Anxiety, Music
The Effect Of Music Listened By Patients With Moderate Dental Anxiety During The Restoration Of Occlusal Caries
It is aimed to evaluate the effect of music listened by patients with moderate dental anxiety during the restoration of posterior occlusal dental caries on vital signs of the participants.
- Conditions
- Dental Anxiety, Music, Physical Stress
- Trial name
- NCT04932759
- Testing
- music listening
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Dental Decay, Periodontal Abscess
ONE-1 Oral graNd Est 1
This study is about the assessment of two oral telemedecine tools compared to an intra oral clinical examination used as a reference among elderly persons living in nursing home.
- Conditions
- Dental Decay, Periodontal Abscess, Periodontitis, Gingivitis
- Trial name
- ONE (NCT05089214)
- Testing
- Intra oral cameras
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Caries,Dental, Tooth Decay
KAP of Dental Practitioners Regarding CRA
The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.
- Conditions
- Caries,Dental, Tooth Decay, Tooth Diseases
- Trial name
- NCT05792215
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Pandemic-adapted Caries Care Multicentre Single-group Interventional Study
The current understanding of dental caries has not been completely transferred into the clinical practice to control caries lesion progression (severity / activity) and the individual risk of caries.
- Trial name
- NCT04666597
- Testing
- Modified CariesCare International management
- Where
- 21 sites in United States, Argentina and 11 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Caries,Dental
Birth to Three - Cavity Free
Early childhood caries (ECC) is a potentially painful and debilitating disease, which represents a significant public health problem among young children.
- Trial name
- BTCF (NCT05756413)
- Testing
- Self-determination theory
- Where
- 16 sites in United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Dental Caries
Family Access to Dentist Study
The study is a multi-site, double blind, parallel arm, community-based randomized controlled trial (phase III RCT) to evaluate the effectiveness of new referral approaches to increase receipt of dental care among inner-city urban…
- Trial name
- FADS (NCT02395120)
- Testing
- Standard letter, Intervention letter, Reduced intervention letter
- Where
- 2 sites in United States
- Volunteers
- 1,305 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dental Caries
Evaluation Of Fluoride Uptake By Dentine Following Silver Diamine Fluoride Under Resin Modified Glass Ionomer Restoration In Carious Primary Molars
Dental caries is one of the most common oral diseases of childhood and is considered as a major public health problem especially in areas with poor access to dental care.
- Trial name
- NCT04777968
- Testing
- Silver diamine fluoride
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children, Vital Pulp Therapy
Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity.
- Trial name
- NCT06372561
- Testing
- Mineral trioxide aggregate (dressing material), Melatonin (dressing material)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University