Clinical trials: Tooth Caries
Dental Caries
Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique
The teeth of the patients that meet inclusion criteria will be anesthetized, isolated with a rubber dam. Cavity opened using conventional high-speed rotary instruments.
- Trial name
- NCT03186261
- Testing
- Nano silver fluoride solution, Cavity Cleanser
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries
Silver Diamine Fluoride Treatment of Active Root Caries Lesions in Older Adults: A Case Series
The authors conducted a case series to determine the outcomes of treatment of root surface caries lesions when the teeth were treated topically with 38% silver diamine fluoride.
- Trial name
- NCT04370080
- Testing
- Silver Diamine Fluoride 38%
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Roseman University of Health Sciences
Dental Caries, Periodontitis
Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets
This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.
- Conditions
- Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission
- Trial name
- NCT07674888
- Testing
- Professional Dental Plaque Disruption
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Decay, Dental
Evaluating the Efficiency of Newly Designed Prefabricated PMMA Crowns for Restoring Primary Teeth in Comparison to Stainless Steel and Zirconia Crowns
Evaluation of PMMA pediatric crowns
- Trial name
- NCT04479046
- Testing
- PMMA crowns
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Tooth Decay, Tooth Restoration
Clinical and Radiographic Evaluation of Two Matrix Systems for Restoration of Class II Cavities in Primary Molars
this study aims to evaluate and compare the clinical and radiographical efficacy, operator ease, satisfaction and patient comfort in restoring class II cavities in primary molars using Fender Mate system with T-band system.
- Trial name
- NCT06447324
- Testing
- Fender Mate matrix system, T-band matrix
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aswan University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Root Caries
Effectiveness on SDF Solution and PVP-I Combined NaF Varnish in Preventing Root Caries in Elders
The main objective of this study is to compare the effectiveness and cost-effectiveness of 4-monthly application of 10% povidone iodine solution followed by 5% sodium fluoride varnish with those of annual application of 38%…
- Trial name
- NCT03654820
- Testing
- PVP-I solution combined with NaF varnish, SDF solution
- Where
- China
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Class V Dental Caries, Composite Resin and Self Adhesive Flowable Composite
One Year Clinical Performance of Self Adhesive Giomer Containing Flowable Composite in Restoring Class V Cavities
This clinical trial will be conducted to compare the clinical performance of self adhesive giomer containing flowable composite and putty nanohybrid resin composite in class V cavities over one year follow-up
- Trial name
- NCT04944485
- Testing
- (FIT SA F03, SHOFU, USA), (Neo Spectra™ ST, Dentsply, Sirona, USA)
- Volunteers
- 46 people
- Sponsor
- Cairo University
Cervical Caries
Nobio Antimicrobial Particles Effect in a Split Mouth Model
The study purpose is to evaluate the antimicrobial effect of Nobio particles incorporated within Novidia Dental Bonding and Flowable Composite versus standard of care within a split mouth model.The study population will include…
- Trial name
- NCT03501784
- Testing
- Nobio particles incorporated within Novidia Dental Bonding, Filtek bond and flow composite
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Nobio Ltd.
Dental Caries Extending to Pulp, Pulp Disease, Dental
The Effect of Different Risk Factors on the Success Rate of VPT
This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure.
- Conditions
- Dental Caries Extending to Pulp, Pulp Disease, Dental, Irreversible Pulpitis, Reversible Pulpitis
- Trial name
- NCT06844448
- Testing
- with Biodentine, with MTA
- Where
- Hungary
- Volunteers
- 400 people
- Sponsor
- Semmelweis University
Dental Caries
Dental and Oral Finding in Israeli Children With Past Intrauterine Growth Retardation (IUGR)
oral status and early childhood caries (ecc) in israeli children with past IUGR
- Trial name
- NCT00867542
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Caries, Dental
Caries Removal Methods and Microbiome Changes
Dental caries management approaches may influence not only tissue removal but also the microbial composition within the cavity. However, clinical evidence on how different caries removal methods affect the oral microbiome remains…
- Trial name
- NCT07538089
- Testing
- Non-selective caries removal, Selective caries removal
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nuh Naci Yazgan University
Dental Caries
The Children's Amalgam Trial
The Children's Amalgam Trial is one of only two randomized trials of its kind, and the only such trial in the United States, to address the potential impact of mercury exposure from amalgam restorations on neuropsychological and…
- Trial name
- NCT00065988
- Testing
- Dispersed phase amalgam restoration /composite restoration
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Carelon Research
Re-mineralization
Re-mineralization Effects of Sugar Free Chewing Gum Sweetened With Different Sugar-substitutes
The purpose of this study is to evaluate the clinical effect of chewing gum containing maltitol, on re-mineralization of early caries following daily chewing for 6 months by school children, compared to a xylitol gum, gum base…
- Trial name
- NCT02468388
- Testing
- maltitol, xylitol, gum base
- Where
- China
- Volunteers
- 482 people
- Sponsor
- Roquette Management (Shanghai) Co., Ltd.
Dental Caries
Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System
The aim of this clinical study is to investigate the impact of the deep margin elevation technique on the clinical performance of CAD/CAM endocrown restorations in deep Class II cavities.
- Trial name
- NCT06222918
- Testing
- Deep Margin Elevation (G-ænial Universal Injectable)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries; Dentin
SMART With Different Modifications in Asymptomatic Deep Carious Lesions of Primary Molars.
This study aimed to evaluate the clinical success of the 'Silver Modified Atraumatic Restorative Technique '(SMART) with different modifications in asymptomatic deep carious lesions of primary molars.
- Trial name
- NCT06645860
- Testing
- SDF+KI+LED Light 20s, SDF+KI
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Caries in Children
Success of Zirconia and Composite Strip Crowns for Primary Incisors
The purpose of this study is to evaluate and compare the clinical and radiographic performance of zirconia and composite strip crowns bonded on primary incisors
- Trial name
- NCT05034003
- Testing
- Zirconia crown, composite strip crown
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries,Dental
Near Infrared Technology for the Detection of Proximal Caries
This study aims to determine the effectiveness of an intraoral scanner with near-infrared imaging (NIRI) for the diagnosis of proximal caries.
- Trial name
- NCT05919576
- Testing
- Near infrared imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Marmara University
Tooth Decay
The Proximal Contact Tightness and Location in Class II Composite Restorations
This study aims to investigate consecutive biological changes in proximal contact tightness using digital force gauge and evaluate proximal contact location using cone beam computed tomography between class II direct composite…
- Trial name
- NCT05749640
- Testing
- Precontoured sectional matrix EZ COAT, PerForm™, AdDent Trimax™
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- karim mohamed
Dental Caries in Children, Diet Habit
Maternal Control of the Child's Feeding, Child's Eating Behavior and Early Childhood Caries in Preschoolers
Dental caries in children is considered one of the most prevalent oral diseases of this age group, leading to significant manifestations presenting as pain, interference with feeding, higher risk of developing dental caries in…
- Conditions
- Dental Caries in Children, Diet Habit, Dietary Exposure, Eating Behavior
- Trial name
- NCT06898918
- Where
- Egypt
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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