Clinical trials: Tooth Discoloration
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Tooth Discoloration
Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment
This observational study evaluated the color stability of darkly discolored arrested caries lesions (DDACL) on anterior teeth following in-office bleaching with 40% hydrogen peroxide, in comparison with healthy teeth.
- Trial name
- NCT07886255
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Gingivitis, Healthy Adult
Comparative Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Nanobiofusion Gingival Gel (NBF), Placebo Gel, and Commercial Toothpaste
The goal of this clinical trial is to learn if Nanibiofusion Gingival Gel (NBF) is able to reduce dental plaque and gum inflammation in adults.
- Trial name
- NCT07850232
- Testing
- Nano Bio-Fusion (NBF) Gingival Gel, Commercial fluoride toothpaste
- Where
- Jordan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Tooth Discoloration, Tooth Staining
Peroxide Versus Non-Peroxide In-Office Tooth Bleaching
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems.
- Trial name
- BECTS (NCT07818031)
- Testing
- peroxide -based in office tooth bleaching, non-peroxide -based in office tooth bleaching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Tooth Stain
Guided Biofilm Therapy Versus Conventional Polishing for Tooth Re-Staining
This study compared Guided Biofilm Therapy with conventional polishing in adults with visible extrinsic tooth staining. Each participant received Guided Biofilm Therapy on one side of the mouth and conventional polishing on the…
- Trial name
- NCT07799558
- Testing
- Guided Biofilm Therapy, Conventional Polishing
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Tooth Whitening, Tooth Discoloration
Clinical Research Study to Evaluate Stain Removal and Whitening Improvement
The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste…
- Trial name
- NCT07870018
- Testing
- Vitamin C toothpaste
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Discoloration
A Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up
The aim of this clinical study is to evaluate the efficacy of an experimental mouthwash used with a marketed whitening toothpaste or a marketed regular fluoride toothpaste, compared to a marketed regular fluoride toothpaste…
- Trial name
- NCT07836998
- Testing
- Whitening Toothpaste, Experimental Mouthwash, Regular Fluoride Toothpaste
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Discoloration Following Root Canal Treatment
TOOTH DİSCOLORATİON AFTER ROOT CANAL TREATMENT WİTH AH PLUS AND BİOROOT RCS
he purpose of this clinical study is to compare tooth color changes after root canal treatment using two different root canal sealers, AH Plus and BioRoot RCS, in upper front teeth.
- Trial name
- NCT07849296
- Testing
- AH Plus Root Canal Sealer, BioRoot RCS Root Canal Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Tooth Discoloration, Tooth Sensitivity
Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching Gel
The goal of this clinical trial is to learn the effect of Nano-fortified Bleaching on whitening and sensitivity of teeth.The main questions it aims to answer are: Does Nano-fortified Bleaching gel is more effective in enhancing…
- Trial name
- NCT06904118
- Testing
- Nano-reinforced Novel Hydrogen peroxide gel, Conventional Hydrogen peroxide gel without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Teeth Staining
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Sensitive Whitening Toothpaste, Containing 5% KNO3 (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains Over 4 Weeks of Unsupervised Use.
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic…
- Trial name
- NCT07761715
- Testing
- Toothpaste
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Teeth Color, Teeth Staining
A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for…
- Trial name
- NCT07214038
- Testing
- toothpaste
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Teeth Staining
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains) Over 8 Weeks of Unsupervised Use.
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic…
- Trial name
- NCT07219342
- Testing
- Toothpaste
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Black Staining
Comparison of Erythritol Air-Polishing and Conventional Polishing Following Ultrasonic Scaling on the Relapse of Chromogenic Tooth Staining in Children
The goal of this randomized clinical trial is to compare the effect of erythritol air-polishing and conventional polishing following ultrasonic scaling on the relapse of chromogenic tooth staining in children aged 4-13 years…
- Trial name
- NCT07730658
- Testing
- Guided Biofilm Therapy with erythritol, Conventional Polishing
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Veneer, Composite Restorations
Clinical Evaluation of Prefabricated Versus 3D-Printed Composite Resin Veneers: in Vivo Study
The purpose of this study is to clinically evaluate prefabricated versus 3D-printed composite resin veneers
- Conditions
- Veneer, Composite Restorations, Teeth Color, Teeth Staining
- Trial name
- NCT07691658
- Testing
- Prefabricated Composite Resin Veneers, 3D-Printed Composite Resin Veneers
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Molar Incisor Hypomineralisation, Enamel Hypomineralization
Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities
This clinical study aimed to compare the effectiveness of two minimally invasive approaches for masking molar-incisor hypomineralization (MIH) opacities and to evaluate esthetic perceptions of children and their parents.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypomineralization, Tooth Discoloration
- Trial name
- NCT07494682
- Testing
- Resin infiltration, Etch Bleach Seal Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Tooth Discoloration
Efficacy of Manual Toothbrushes in Removing Tooth Stains
Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.
- Trial name
- NCT06486974
- Testing
- NaF, Na MFP
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Tooth Discoloration
A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent
The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
- Trial name
- NCT06782087
- Testing
- nano chitosan
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology