Clinical trials: Tooth Diseases
Endodontic Disease, Endodontically Treated Teeth
Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis
Problem statement: The post-operative pain after endodontic treatment. aim of study: The study is aiming to compare postoperative pain after submucosal cold saline injection (submucosal cryotherapy) (SMC) versus intra-canal…
- Trial name
- NCT06304259
- Testing
- Saline
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- October 6 University
Tooth Extraction, Periapical Infections
Cortical Lamina for Alveolar Ridge Preservation
This randomized controlled clinical trial aims to evaluate the efficacy of placing a cortical lamina between the elevated flap and buccal bone plate following tooth extraction for preserving alveolar ridge dimensions.
- Conditions
- Tooth Extraction, Periapical Infections, Tooth Fracture, Periodontal Disease, AVDC Stage 4
- Trial name
- Lamina (NCT07231874)
- Testing
- Cortical Lamina Technique, Natural Healing (Control)
- Where
- Cuba
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Dental Caries in Children, Tooth Diseases
Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars
The purpose of this randomized clinical trial is to compare the clinical/radiographic success of Hall technique and modified Hall technique in the treatment of primary molars with deep dentine carious lesions in children…
- Conditions
- Dental Caries in Children, Tooth Diseases, Tooth Demineralization, Stomatognathic Diseases
- Trial name
- NCT05220865
- Testing
- Hall Technique, Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Tooth Diseases
Clinical Evaluation of Three Different Universal Adhesives in Non-carious Cervical Lesions
The aim of this randomized, controlled prospective clinical trial is to evaluate and compare the performances of three different universal adhesives using a flowable universal composite resin in the restoration of non-caries…
- Trial name
- NCT03415412
- Testing
- Clearfil Univesal Bond, IBond Universal, G-Premio Bond
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries (Diagnosis), Diagnostic Imaging
Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years
The goal of this observational study is to compare the diagnostic performance of three detection methods for approximal carious lesions in primary molars among pediatric patients aged 4-10 years.
- Conditions
- Dental Caries (Diagnosis), Diagnostic Imaging, Optical Imaging, Radiographic Image Interpretation, Computer-Assisted
- Trial name
- NILT (NCT07041164)
- Testing
- Bitewing radiograph, Near-infrared light transillumination
- Where
- 2 sites in Thailand
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Sawanya Prutthithaworn
Polyneuropathy, Charcot Marie Tooth Disease (CMT)
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and…
- Trial name
- PNP (NCT07152197)
- Testing
- Progressive Resistance Exercise Training
- Where
- 2 sites in Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Tooth Ankylosis, Cemento-Osseous Dysplasia
RFA and Bite Force in COD Teeth
This study aims to evaluate the periodontal attachment and ankylosis status of teeth associated with cemento-osseous dysplasia (COD).
- Conditions
- Tooth Ankylosis, Cemento-Osseous Dysplasia, Jaw Diseases / Diagnosis
- Trial name
- NCT07185711
- Testing
- Resonance Frequency Analysis (RFA), Bite Force Sensor
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Gingivitis, Periodontal Diseases
Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems
Although the well-known detrimental effects of conventional cigarette smoking on oral health, there are still lack of evidences about the impact of less harmful alternatives (such as electronic cigarettes or heat not burn…
- Trial name
- SMILE (NCT04649645)
- Testing
- TOBACCO CIGARETTES, COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS), NOT SMOKING
- Where
- Italy
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Eclat Srl.
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Periodontal Diseases, Tooth Loss
Internalized Stigma and Tooth Loss Due to Periodontitis
Internalized stigma refers to the adoption of negative judgments, beliefs, stereotypes and stigmatizing views imposed by society.
- Trial name
- NCT07065019
- Testing
- The Internalized Stigma Scale in Mental Illness (ISS)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Neuromuscular Diseases, Hemiparesis
Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients
The instrumental evaluation of standing postural control by posturographic analysis supplements the clinical evaluation and, as such, is recommended by the French National Authority for Health (HAS 2007).
- Conditions
- Neuromuscular Diseases, Hemiparesis, Charcot-Marie-Tooth Disease
- Trial name
- KPLATES (NCT04283175)
- Testing
- Posturological examination on KPlates and AMTI platforms, Berg Balance Scale (BBS)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy
Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study
The objective of the ActiLiège Next study is to collect longitudinal data from patients and control subjects using a wearable magneto-inertial device.
- Conditions
- Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy, Myotonic Dystrophy 1, Charcot-Marie-Tooth
- Trial name
- NCT05982119
- Testing
- ActiMyo/Syde
- Where
- 8 sites in Belgium, Czechia and 5 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE)
The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes
Determine if the daily docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) supplement will reduce serum levels of biomarkers of sub-concussion injuries over a course of American football season among collegiate football…
- Trial name
- NCT04796207
- Testing
- Fish Oil (DPA+EPA 2:1 ratio) Capsules, High Oleic Safflower Oil Capsules
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Carpal Tunnel Syndrome
Topical Cannabidiol for Treating Carpal Tunnel Syndrome
The Purpose of this study is to assess the safety and efficacy of Cannabidiol on treatment of Carpal Tunnel Syndrome.
- Trial name
- NCT06108349
- Testing
- Cannabidiol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Tooth Diseases, Piezoelectric Technique
A New Piezoelectric Technique in Third Molar Surgery
The present study aims to analyze the effect of the piezoelectric technique in third molar surgery in terms of facial swelling, trismus and pain in a split-mouth randomized controlled clinical trial
- Conditions
- Tooth Diseases, Piezoelectric Technique, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06212232
- Testing
- Piezoelectric surgery
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Anxiety and Fear, Tooth Disease
Virtual Reality Used During Tooth Extraction and Extirpation Treatment
This study carriy out to evaluate the effect of virtual reality glasses used during tooth extraction and extirpation treatment under local anesthesia on anxiety and fear in children aged 7-10 years.
- Trial name
- NCT06315816
- Testing
- virtual reality glasses used during tooth extraction and extirpation treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Murat Bektaş
Charcot-Marie-Tooth Disease, Healthy
Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for IPSC Generation and Biobanking
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Charcot-Marie-Tooth disease research and drug development by using cells from the body (such as skin or blood cells) to make…
- Trial name
- NCT06203093
- Testing
- Biological Sample Collection
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Stem Cell Foundation Research Institute
Charcot-Marie-Tooth Disease, Hereditary Neuropathy With Hypersensitivity to Pressure
EVALUATION OF SERUM INFLAMMATORY CYTOKINE CONCENTRATION IN HEREDITARY SENSITIVOMOTOR NEUROPATHIES
The most common forms of hereditary neuropathy are Charcot-Marie-Tooth disease (CMT) and hereditary neuropathy with hypersensitivity to pressure (HNPP) or tomacular neuropathy.
- Trial name
- CytokinesUS (NCT06808581)
- Testing
- blood test for pro-inflammatory cytokines and ultrasound of the median nerves
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice