Clinical trials: Tooth Hypersensitivity
Dentin Sensitivity, Oral Hygiene
A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
The main aim of this study is to investigate the ability of an experimental dentifrice containing 5 percent (%) potassium nitrate (KNO3), 1% alumina and 5% sodium tripolyphosphate (STP), to maintain tooth color and reduce…
- Trial name
- NCT06150573
- Testing
- Test Dentifrice, Reference Dentifrice (Aquafresh Cavity Protection)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
Dentine Tubule Occlusion Assessment in a Modified in Situ Model
This will be a single centre, single blind, randomized, three treatment, three period crossover design, modified, in situ, study in healthy participants.
- Trial name
- NCT02768194
- Testing
- Stannous fluoride, Sodium monofluorophosphate, Mineral water
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity, Tooth Bleaching
Evaluation of Sensitivity With and Without Sonic Activation of a Desensitizing Gel Before in Office Bleaching in Adults
This randomized, controlled clinical trial, triple-blind, split-mouth type was conducted aiming to assess the absolute risk of sensitivity with and without sonic activation of a desensitizing gel previously to the in-office…
- Trial name
- NCT03039270
- Testing
- With sonic activation (SMART Device®), Control (Without sonic activation)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Federal University of Amazonas
Dentin Hypersensitivity
Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivity (A 6m Randomized Clinical Trial)
The aim of the study to compare the clinical effectiveness of Episodic use of Bioactive Silica Based versus continuous use of fluoride based desensitizing toothpastes in management of dentin hypersensitivity (DH) of adult…
- Trial name
- NCT07120139
- Testing
- episodic use of the desensitizing toothpaste, continuous use of the conventional desensitizing toothpaste
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Tooth Sensitivity, Tooth Bleaching
Photobiomodulation Before or After Tooth Whitening
The objective is to evaluate the effect of photobiomodulation (PBM) applied before or after in-office tooth whitening in reducing tooth sensitivity (TS) and color change.
- Conditions
- Tooth Sensitivity, Tooth Bleaching, Laser Therapy
- Trial name
- NCT06518629
- Testing
- Photobiomodulation with low power laser
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Placebo and Post-bleaching Sensitivity
Purpose: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT03065673
- Testing
- Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flavia Pardo Salata Nahsan
Color; Change Teeth, Posteruptive
Clinical Comparison of LED- and Diode Laser-activated Bleaching
To clinically compare the effects of LED- or Diode laser-activated bleaching on colour change, tooth-sensitivity, gingival-irritation and temperature variation over 9-months.
- Trial name
- NCT04537754
- Testing
- bleaching device
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tooth Hypersensitivity
the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity
to solve the problem of hypersensitivity, I will use two different materials ( Giomer versus Sodium Fluoride) and compare between their effects in reliving the symptoms
- Trial name
- NCT03818945
- Testing
- shofu PRG barrier coat, Sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentine Hypersensitivity
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls.
- Trial name
- NCT01827670
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dentine Hypersensitivity
Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over a two week treatment period.
- Trial name
- NCT01592851
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Sensitivity, Toothache
Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching
Objectives: This study aims to evaluate the effectiveness of preemptive administration of non-steroidal anti-inflammatory Piroxicam-beta-Cyclodextrin on risk and level of tooth sensitivity caused by in-office bleaching procedures…
- Trial name
- NCT03153657
- Testing
- Piroxicam-Beta-Cyclodextrin
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentin Sensitivity
Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity
The purpose of this study is to compare the clinical efficacy of test fluoride dentifrice in reducing Dentin Hypersensitivity (DH) with that of a standard fluoride dentifrice, as measured by evaporative air sensitivity after 12…
- Trial name
- NCT07317128
- Testing
- Test Dentifrice, Colgate Sensitive ProRelief, Colgate Triple Protection
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
Effect of Glutaraldehyde-based Desensitizer in the Control of Tooth Sensitivity and Tooth Color Post- Whitening
Tooth whitening is one of the most indicated aesthetic procedures in dentistry and there is evidence that it interferes with aspects of patients' quality of life.
- Trial name
- NCT05309967
- Testing
- GLUMA DESINSITIZER
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Asthma, Dental Caries
Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers
Young children with asthma who use drugs for their asthma are at higher risk for tooth decay. These drugs can cause (1) dry mouth from less saliva secretion and (2) acid mouth that causes teeth to become soft and bacteria to…
- Trial name
- Lollipops (NCT01147835)
- Testing
- Chinese Licorice Root
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dental Pulp Disease, Dental Pain and Sensation Disorder
Comparison of Post Cementation Sensitivity Between RMGIC and GIC as Luting Materials in a Randomized Clinical Trial
This randomized controlled trial aims to compare post-cementation sensitivity between resin-modified glass ionomer cement (RMGIC) and conventional glass ionomer cement (GIC) as luting materials.
- Trial name
- RMGICvsGIC (NCT07102121)
- Testing
- luting material applaication with Modified Glass Ionomer Cement (RMGIC)
- Where
- Pakistan
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Saidu College of Dentistry
Dentin Sensitivity
Dentine Hypersensitivity Management KAP Study
The study aims to assess and compare the knowledge, attitudes, and practices of Egyptian and Nigerian dentists on etiology, diagnosis, and management of DH.
- Trial name
- NCT06582238
- Testing
- Dentists in Clinical Practice
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Muhammad Modu
Tooth Whitening
Evaluate the Efficacy and the Tolerance of the Medical Device V063B-DP3003 on Dentin Hypersensitivity During Teeth Whitening
A dental gel intended to relieve pain related to dentin hyper sensitivity is commercialized in several countries worlwide since May 2017. Its efficacy and tolerance has already been proven in dentin hyper sensitivity.
- Trial name
- NCT05804994
- Testing
- Elgydium Clinic Sensileave Gel (V063B - DP3003)
- Where
- Poland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Dentin Sensitivity
CPP-ACPF and Laser's Effect on Dentin Hypersensitivity
The aim of this study was to evaluate the effect of casein phosphopeptide amorphous calcium phosphate fluoride paste (CPP-ACPF) associated with low level laser therapy (LLLT) in the symptomatology and on the quality of life of…
- Trial name
- NCT03750851
- Testing
- CPPACPF, Laser, LaserCPPACPF
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Sensitivity
To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)
This single centre study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a standard fluoride…
- Trial name
- NCT02923895
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline