Clinical trials: Tooth Lost, open to volunteers
Jaw, Edentulous, Partially, Missing Teeth
Two-unit Cantilever Implant Prostheses Made of Monolithic Zirconia or PFM
The aim of is to compare the survival rate and technical outcomes of cantilever implant-supported fixed denture prosthetics (cFDPs) made either out of monolithic zirconia bonded to a titanium base in a digital workflow, or…
- Trial name
- Cantilever (NCT04713800)
- Testing
- Monolithic zirconia screw retained implant-supported cantilever reconstruction supported by titanium base abutments, in a full digital workflow (ZR-TiB), porcelain fused-to metal screw retained implant-supported cantilever reconstruction supported by a gold-abutment, in a conventional workflow (PFM-GA)
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Tooth Loss
Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar Region
This randomized clinical trial will evaluate the effect of using an enamel matrix derivative during immediate dental implant placement in the mandibular molar region.
- Trial name
- NCT07727655
- Testing
- Enamel Matrix Derivative (Emdogain), Immediate Dental Implant Placement
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Partially Edentulous Jaw, Tooth Loss
Clinical Safety and Effectiveness of the Straumann Dynamic Navigation System Falcon
The Falcon Study is a prospective, multicenter, multinational clinical investigation evaluating the Straumann® Dynamic Navigation System (Falcon) for dental implant placement.
- Conditions
- Partially Edentulous Jaw, Tooth Loss, Dental Implant
- Trial name
- Falcon (NCT07518615)
- Testing
- Post-operative Cone Beam Computed Tomography (CBCT), Straumann Falcon Dynamic Navigation System, Dental Implants
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 75 people
- Sponsor
- Institut Straumann AG
Tooth Loss
A Clinical Study of the TSX Dental Implant System (Xpresso)
A prospective, observational, multicenter study where 62 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant…
- Trial name
- Xpresso (NCT06571812)
- Testing
- TSX
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- ZimVie
Dental Implants, Single Tooth Lost
5-year Follow up Study on the Comparative Performance of Two-piece Zirconia and Titanium Implants
A post-market, randomized-controlled, superiority clinical study to compare medium-term performance and safety of the Straumann PURE 2-piece Ceramic Implant with Straumann Bone Level Implant using a fully digital workflow.
- Conditions
- Dental Implants, Single Tooth Lost, Dental Implant Failed
- Trial name
- PostNCT0390817 (NCT05326880)
- Testing
- Ceramic Dental Implant, Titanium Dental Implant
- Where
- 2 sites in Germany, Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Tooth Loss, Dental Implant
Clinical Performance of Nobel N1 System
The purpose of the study is to evaluate whether N1 dental implants are successful when a final crown is placed on them at 6 weeks from implant placement surgery.
- Trial name
- NCT07280260
- Testing
- Nobel N1 implant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Tooth Loss, Dental Implant
Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment
The goal of this clinical trial is to evaluate whether an anatomical prefabricated healing abutment (AHA) improves tissue preservation and clinical outcomes following immediate implant placement after tooth extraction in adults.
- Conditions
- Tooth Loss, Dental Implant, Clinical Trials, Randomized Controlled Trial
- Trial name
- Aharct (NCT07727980)
- Testing
- scannable anatomical healing abutment, Standard Healing Abutment for Dental Implants
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Premature Loss of Primary Molars, Space Maintenance
Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital Scanning
This prospective split-mouth clinical study aims to evaluate space changes in the mandibular dental arch following premature extraction of the lower first primary molar in children aged 3 to 5.5 years.
- Conditions
- Premature Loss of Primary Molars, Space Maintenance, Dental Arch Development, Pediatric Tooth Extraction
- Trial name
- NCT06965777
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Pulp Necrosis, Pulpitis
Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols
Achieving effective root canal disinfection while minimizing postoperative pain is a critical goal in endodontic therapy. Advanced irrigation protocols, such as ultrasonic activation, laser activation, negative pressure…
- Trial name
- NCT07546773
- Testing
- Ultrasonic Irrigation Activation, Laser-Activated Irrigation, Mechanical Irrigation Activation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Tooth Loss
Research on the Development and Clinical Evaluation of Biomimetic Abutments
This study aims to evaluate the clinical effectiveness of biomimetic abutments in implant restoration.
- Trial name
- NCT06870955
- Testing
- using biomimetic abutments
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Edentulous Mouth, Quality of Life
Changes in Oral Health-related Quality of Life (OHRQoL) During Full Arch Implant Treatment
Full-arch implant-supported fixed dental prostheses are a widely accepted treatment for edentulous patients, with high long-term implant survival rates.
- Conditions
- Edentulous Mouth, Quality of Life, Tooth Loss, Oral Health Quality of Life (OHQoL) Was Assessed
- Trial name
- NCT07568249
- Testing
- Full Arch Implant Surgery, Full arch prosthesis
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Implantology Institute
Tooth Loss
3D Autotransplantation of Teeth
The study aims to clarify the usefulness of 3D-printed replicas in association with autotransplantation of teeth in children and young adults.
- Trial name
- NCT04120688
- Testing
- 3D generated tooth replica
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Partial Edentulism, Tooth Loss / Rehabilitation
In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery
This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery.
- Trial name
- NCT07315607
- Testing
- Fully Guided Implant Placement and Immediate Provisionalization
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Edentulism
Russian Version of OHIP-EDENT-19 for Adults With Complete Tooth Loss
The Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT-19) is a 19-question survey about how complete tooth loss and dentures affect daily life.
- Trial name
- OHIP-EDENT-RU (NCT07904117)
- Where
- Russia
- Volunteers
- 330 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Edentulous Jaw, Tooth Loss
Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites
The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time.
- Conditions
- Edentulous Jaw, Tooth Loss, Toothless Mouth
- Trial name
- NCT07177521
- Testing
- Insertion of implants in post-extraction tooth
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Teeth Absent, Teeth Missing
Multicenter Clinical Study on the Efficacy and Esthetic Outcomes of Immediate Implant Placement Using the Socket-Shield Technique Versus Conventional Immediate Implantation in the Anterior Maxillary Esthetic Zone
This study plans to enroll no fewer than 48 adult patients who have non-restorable maxillary anterior teeth due to trauma or dental diseases and are candidates for immediate implant placement, meeting the inclusion and exclusion…
- Conditions
- Teeth Absent, Teeth Missing, Dental Implant
- Trial name
- NCT07822685
- Testing
- the Socket Shield Technique (SST) immediate implant placement, Conventional immediate implant placement
- Volunteers
- 48 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Dental Caries
LT Comparative Effectiveness of 2 Caries Treatments
This study is a continuation of a cluster randomized clinical trial (cRCT) conducted in 33 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio.
- Trial name
- NCT07213661
- Testing
- A "simple medical strategy" consisting of silver diamine fluoride (SDF), A "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss, Alveolar Bone Regeneration Following Odontectomy
Effect of Ascorbic Acid-Loaded I-PRF With Partially Demineralized Dentin Graft on Alveolar Ridge Preservation
The goal of this clinical trial is to find out which treatment best preserves the jawbone after tooth extraction in adults planning to receive a dental implant later.
- Conditions
- Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss, Alveolar Bone Regeneration Following Odontectomy, Assisted Alveolar Bone Healing After Dental Extraction, Alveolar Bone Preservation
- Trial name
- AA-IPRF-PDDG (NCT07916545)
- Testing
- Alveolar Ridge Preservation Using Partially Demineralized Dentin Graft alone, Alveolar Ridge Preservation Using PDDG Combined with I-PRF, Alveolar Ridge Preservation Using PDDG Combined with Ascorbic Acid-Loaded I-PRF
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nahda University
Tooth Loss / Rehabilitation, Tooth Extraction
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
This randomized controlled trial compares two provisional socket-sealing concepts following single non-molar tooth extraction and alveolar ridge preservation: a fixed, tooth-supported, 3D-printed ovate pontic provisional…
- Conditions
- Tooth Loss / Rehabilitation, Tooth Extraction, Alveolar Bone Loss, Alveolar Ridge Augmentation
- Trial name
- Pontic-Essix (NCT07748871)
- Testing
- Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Tooth Loss
Allogenic Bone Block for Oro-Antral Communication Closure for Subsequent Implant Placement
13 patients will be included in this study with a badly destructed upper molar indicated for extraction. Cone beam computerized tomography images revealed the presence of a large bone defect associated with oro-antral…
- Trial name
- CAD-CAM (NCT07604142)
- Testing
- Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University