Clinical trials: Tooth Movement, open to volunteers
Mixed Dentition Using Sequential Dental Aligners
This Study Will Examine Shortened Treatment Wear Time for Patients With Mixed Dentition Using AirFlex Aligner, Sequential Dental Aligners.
This study will examine shortened treatment wear time for patients with mixed dentition using sequential dental aligners. Using the existing AirFlex aligner design that patients with permanent dentition use, it may be possible to…
- Trial name
- NCT07220317
- Testing
- Sequential Aligners
- Volunteers
- 45 people
- Sponsor
- OrthoFX
TMD/Orofacial Pain, Malocclusions
Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.
- Trial name
- NCT07828041
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Malocclusion Class I
Diode Laser Versus LED for Maxillary Canine Retraction in Orthodontic Patients
This study aims to compare the effects of diode laser and light-emitting diode (LED) photobiomodulation on maxillary canine retraction during fixed orthodontic treatment.
- Trial name
- NCT07810699
- Testing
- Diode Laser Photobiomodulation, LED Photobiomodulation
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Accelerate Tooth Movement
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation (Comparative Clinical Study)
- Trial name
- LLLT- piezo (NCT07873853)
- Testing
- low level LAZER therapy., Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods., Piezocision-assisted orthodontic retraction
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Wear, Orthodontic Extrusion
Orthodontic and Articular Effects of the One-Step No-Prep Protocol
This study investigates how the One-Step No-Prep protocol with orthodontic assistance affects dental and jaw function in adults treated for localized tooth wear.
- Trial name
- OSNPO (NCT07533240)
- Testing
- Low-dose Cone-Beam Computed Tomography
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Mainjot Amélie
Malocclusions, Canine Retraction
Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison.
- Trial name
- NCT07455656
- Testing
- patients will receive local application of vitamin D3 combined with corticision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Rate of Tooth Movement in Orthodontic Patients
Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial
it is a randomized control trial and aims at investigating the effects of PRF on rate of tooth movement and root length to be tested on larger sample size of pakistani population
- Trial name
- NCT06634017
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Lower Anterior Crowding
Evaluation of Accuracy of 3D Printed Aligners in Comparison to Thermoformed Aligners in Orthodontic Patients
The goal of this randomized clinical trial is to compare the accuracy of tooth movement achieved by 3D printed aligners versus thermoformed aligners in patients with lower anterior crowding.
- Trial name
- Aligner (NCT07496892)
- Testing
- 3d printed aligner, thermoformed aligner
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Parkinson Disease
Lithium for Parkinson's: an Extension Trial
This study will examine the effects of 24 weeks of lithium therapy achieving serum lithium levels of 0.25-0.50mmol/L on MRI and blood-based biomarkers in Parkinson's disease patients who have completed one of our current 24-week…
- Trial name
- NCT06592014
- Testing
- Lithium aspartate
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- State University of New York at Buffalo
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Tooth Movement, Intrusion of Tooth
Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Evaluation of root resorption following different mandibular incisors intrusive mechanics : A randomized clinical trial
- Conditions
- Orthodontic Tooth Movement, Intrusion of Tooth, Resorption, Root
- Trial name
- NCT05414019
- Testing
- Mini-screw, Utility arch, Nitinol reverse curve wire
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusions
Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy
The goal of this interventional research is to determine the impact of vitamin D intake on substances in saliva, pain, tooth movement, and the density of the bone around teeth in patients during orthodontic treatment.
- Trial name
- NCT07299552
- Testing
- Vitamin D (Calcitriol)
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Hospital Universiti Sains Malaysia
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Accelerated Orthodontic Tooth Movement
Comparing MOP, Prostaglandin E1, and Calcitriol to Accelerate Orthodontic Tooth Movement
This study will compare the effects of MOP (micro-osteoperforation), prostaglandin E1, and calcitriol on the rate of orthodontic tooth movement.
- Trial name
- acceleration (NCT07842120)
- Testing
- PGE₁ (pharmacological) • Agent: Prostaglandin E1, Calcitriol (1,25-(OH)₂D₃) local injection • Agent: Calcitriol (1,25-(OH)₂D₃) Vitamin D3, microosteoperforation MOP (surgical)
- Where
- 2 sites in Iraq
- Volunteers
- 60 people
- Sponsor
- Ghufran Dhari Awad
Relapsing Remitting Multiple Sclerosis (RRMS)
ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS
The exploratory ELIOS study aims to assess the value of novel investigational Eye Movement Biomarkers (EMBs) in tracking disease-related changes among a real-world cohort of Canadian patients with active RRMS, within the context…
- Trial name
- ELIOS (NCT06733922)
- Testing
- ETNATM-ProgMS
- Where
- 14 sites in Canada
- Volunteers
- 224 people
- Sponsor
- Novartis Pharmaceuticals
Dental Malocclusion, Maxillary Deficiency
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy…
- Trial name
- Piezo_Ortho (NCT06315348)
- Testing
- flapless alveolar decortication with augmentation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Orthodontics
Study of the Use of Orthopulse Photobiomodulation
This PMCF study evaluates the safety and performance of OrthoPulse photobiomodulation to accelerate tooth movement during alignment with fixed appliances.
- Trial name
- NCT05650359
- Testing
- OrthoPulse, No intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biolux Technology GmbH
Malocclusion of Anterior Teeth
Clinical Evaluation of Zirconium Dioxide Nano-Coated Arch Wires
"This clinical trial aims to evaluate the clinical performance and efficiency of zirconium dioxide nano-coated orthodontic archwires compared to conventional archwires.
- Trial name
- NCT07813117
- Testing
- Zirconium dioxide nano-coated archwire, Conventional orthodontic archwire
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University