Clinical trials: Tooth Movement Techniques
Tooth Crowding, Dental Crowding
Analysis of Orthodontic Tooth Movement Using 3D Imaging
Purpose: This project aims to study the effects of wire dimension and ligation method (bracket type) on the first stage of orthodontic treatment using 3D imaging.
- Conditions
- Tooth Crowding, Dental Crowding, Malocclusion
- Trial name
- NCT03398798
- Testing
- .014", .016", Twin brackets
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Malocclusion
The Regulation of Osteoprotegerin by Mechanical Stimulation
To test whether levels of OPG can be changed during orthodontic treatment. Alveolar bone samples will be collected from partially impacted third molars after orthodontic uprighting for different period of time in volunteers.
- Trial name
- NCT00155311
- Testing
- orthodontic treatment
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Malocclusion, Angle Class III
Periodontal Ligament Stress Level and Tooth Movement
Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling.
- Trial name
- NCT00099814
- Testing
- Two different loop designs which deliver distinctive forces
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Orthodontic Tooth Movement
Evaluation of the Rate of Maxillary En-masse Retraction Using 0.018-inch Versus 0.022-inch Slot Brackets in Adults
The study compares the rate of en-masse retraction using 0.018-inch versus 0.022-inch slot orthodontic bracket systems in adult patients with maxillary dentoalveolar protrusion.
- Trial name
- NCT04468295
- Testing
- Bonding, Leveling and alignment, Extraction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non-Pharmacological Pain Management, Orthodontic Discomfort
TENS Device Use for Discomfort Relief During Orthodontic Tooth Movement
The goal of this clinical trial is to learn if Transcutaneous Electric Nerve Stimulation (TENS) device works to reduce discomfort during orthodontic treatment, by using orthodontic separators to mimic the discomfort of braces.
- Trial name
- TENS OTM (NCT07687810)
- Testing
- TENS Device
- Where
- United Arab Emirates
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ajman University
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Orthodontics
Study of the Use of Orthopulse Photobiomodulation
This PMCF study evaluates the safety and performance of OrthoPulse photobiomodulation to accelerate tooth movement during alignment with fixed appliances.
- Trial name
- NCT05650359
- Testing
- OrthoPulse, No intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biolux Technology GmbH
Orthodontic Tooth Movement
GCF Volume Changes in Aligners and Fixed Appliances
Orthodontic tooth movement induces biological responses in periodontal tissues that can be reflected by changes in gingival crevicular fluid (GCF).
- Trial name
- GCF-OTM (NCT07480538)
- Testing
- Clear Aligner Therapy, Fixed Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Orthodontic Appliance Complication
Influence of Low Level Laser Therapy on the Rate of Orthodontic Tooth Movement and Associated Pain
This is a single blind randomized controlled trial with split mouth design including 45 patients with extractions of maxillary 1st bicuspids.
- Trial name
- NCT05120102
- Testing
- Diode laser
- Where
- Pakistan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Mesial Movement of Teeth
Full Thickness Mucoperiosteal Flap Versus Low Level Laser in Orthodontic Tooth Movement Acceleration
This study aimed to evaluate the effect of using full thickness mucoperiosteal flap (FTMPF) elevation only versus low level laser therapy (LLLT) on acceleration of orthodontic tooth movement.
- Trial name
- NCT04055935
- Testing
- elevation of full thickness mucoperiosteal flap, low level laser therapy
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Appliance
Speed of Premolar Extraction Space Closure: Every Visit Replacement of Working Archwire
The aims of this trial were to assess the effect of changing 0.019X0.025-inch SS working archwire monthly on the rate of space closure, to compare the frictional resistance of unchanged and new working archwires in-vitro, and to…
- Trial name
- NCT04549987
- Testing
- Space closure without changing working archwire monthly, Space closure withchanging working archwire monthly
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Malocclusion, Tooth Movement Techniques
Efficacy of Orthodontic Tooth Movement Using Beveled and Conventional Attachments in Aligners
The objective of this study is to evaluate the efficacy of tooth movement using beveled attachments and conventional attachments.
- Trial name
- NCT06873932
- Testing
- Arm 1: Beveled Attachments, Conventional Rectangular Attachments
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Neodent
Cytokine Measurements, Orthodontic Space Closure
Biological Markers Evaluation of Accelerated Tooth Movement
Gingival Crevicular Fluid samples will be collected using periopapers after accelerated tooth movement technique, results will be assessed with biomarkers levels done using ELISA Assays
- Conditions
- Cytokine Measurements, Orthodontic Space Closure, Tooth Movement
- Trial name
- NCT02887547
- Testing
- micro-osteoperforation
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth, Impacted, Molar, Third
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement
The purpose of this study is to test whether the two MMPs can be up-regulated during orthodontic treatment. Alveolar bone samples will be collected from partially impacted third molars after orthodontic uprighting for different…
- Trial name
- NCT00154518
- Testing
- Orthodontic treatment
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Rapid Prototyping in Dentures
Complete Denture Tooth Movement in Digital Light Processing Versus Conventional Fabrication Techniques
The purposes of this study are to compare the denture tooth movement, the amount of occlusal adjustment needed and the chairside time required for CAD-CAM and conventional dentures.
- Trial name
- NCT04025697
- Testing
- Complete Denture, Rapid prototyped denture
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Tooth Movement, Low Level Laser Therapy
Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined
Orthodontic treatment is often prolonged, requiring years to achieve desirable outcomes. The prolonged duration of treatment increases the risk of complications such as root resorption, periodontal damage, and patient…
- Conditions
- Orthodontic Tooth Movement, Low Level Laser Therapy, Canine Retraction
- Trial name
- NCT07626580
- Testing
- Micro-osteoperforation, Low Level Laser Therapy and Micro-osteoperforations Combined
- Where
- Pakistan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Class II Division 1 Malocclusion
Evaluation of Micro-osteoperforation on Rate of Maxillary En-masse Retraction
accelerated anterior teeth retraction with the help of microosteoperforation procedure and miniscrews.
- Trial name
- NCT03764189
- Testing
- microosteoperforation
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication
Photobiomodulation and Root Resorption
Objectives: The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group. Materials and Methods: 30 patients, who were admitted to the ………….
- Conditions
- Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication, Orthodontic Tooth Movement
- Trial name
- NCT04044989
- Testing
- Laser, light-emitting diode (LED)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Mesial Movement of Teeth, Miniscrew Stability
Effect of Shock Waves on Tooth Movement and Miniscrew Stability
The low-energy extracorporal shockwave is a scientifically approved method to activate respectively increase bone-turnover processes especially in orthopedic medicine.
- Trial name
- NCT01695928
- Testing
- Extracorporeal shockwave therapy
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna