Clinical trials: Tooth Plaque
Periodontitis, Peri-implant Mucositis
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant…
- Conditions
- Periodontitis, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT05834946
- Testing
- Megagen implant placement, Biomate-Swiss implant
- Where
- Malaysia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gingivitis, Plaque, Dental
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of…
- Trial name
- NCT06300866
- Testing
- Test, Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingiviits
Comparion of Effects of Two Different Power Toothbrushes on Plaque and Gum Health
The goal of this clinical trial is to learn if powered toothbrushing with a side-to-side motion is more effective than powered toothbrushing with oscillating-rotation motion in removing dental plaque.
- Trial name
- NCT07813546
- Testing
- oscillating-rotating powered toothbrush, side-to-side powered toothbrush
- Where
- United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Dental Plaque and Gingivitis
The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.
- Trial name
- NCT02243046
- Testing
- Control toothpaste, Experimental toothpaste, Active Comparator
- Where
- Dominican Republic
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
The objective of this clinical research study is to assess the efficacy of a commercially available triclosan/copolymer toothpaste compared to a commercially available oral hygiene multi-component regimen encompassing the use of…
- Trial name
- NCT02366689
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque
Clinical Study to Compare Dental Plaque Control
This clinical study was to evaluate the control of dental plaque formation after toothbrushing for 4 days with each of the 4 study toothpastes.
- Trial name
- NCT00758394
- Testing
- Fluoride, Triclosan/Fluoride
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Dental Plaque Accumulation
Essential Oils Mouth Rinse and Dental Floss: Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation
It is difficult to obtain patient's compliance with regular interproximal dental hygiene. Dental floss is recognized as an effective procedure to remove dental plaque and prevent gingivitis in the space between teeth, but it is…
- Trial name
- NCT01236963
- Testing
- Essential oils mouthrinse, Dental Floss
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Periodontitis, Alzheimer Disease
Oral Bacterial and Viral Mapping by Dental Plaque in Elderly Patients With and Without Alzheimer's Disease(ORal MICrobiology in Alzheimer's Patients)
The neurological disorders that accompany aging represent a major public health problem. The management of these diseases is a major medical and social priority.
- Trial name
- ORAMICAL (NCT04869904)
- Testing
- dental and plaque sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Periimplantitis, Dental Plaque
Antimicrobial Activity of Two Mouthwashes
This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.
- Conditions
- Periimplantitis, Dental Plaque, Periodontal Diseases, Caries
- Trial name
- NCT02375178
- Testing
- chlorhexidine, Polyhexamethylene biguanide, Sterile saline solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Gingivitis, Gingival Diseases
Effectiveness in Dental Plaque Reduction of Mouthwashes Containing Fatty Acids Compounds (F.A.G.) or Stannous Fluoride
Comparative study on the efficacy of two mouthwashes Containing Fatty Acids Compounds (F.A.G.) or Stannous Fluoride in the reduction of plaque score in individuals with spontaneous gengivitis
- Trial name
- NCT04977778
- Testing
- Fatty Acids Compounds (F.A.G.) Mouthwash, Stannous Fluoride (SF) Mouthwash
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Dental Calculus
Testing if Tartarase Can Remove Dental Tartar
This study was designed to find our whether a novel toothpaste containing safe digestive enzymes (Tartarase) was able to remove pre-existing dental tartar when compared to a well-known toothpaste (Crest).
- Trial name
- NCT06139835
- Testing
- Tartarase
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pontis Biologics, Inc.
Dental Caries, Dental Plaque
Comparative Effectiveness of Various Educational Approaches on Oral Hygiene
Background: Dental caries constitutes a major global public health challenge, posing substantial burdens on both oral health outcomes and healthcare systems worldwide, with far-reaching implications for prevention, treatment, and…
- Trial name
- NCT06910501
- Testing
- Traditional oral hygiene instruction, Digital slide-based education, Brush DJ mobile appliaction
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ege University
Peri-implant Mucositis, Peri-Implantitis
Dental Implant Care and Oral Hygiene Practices
Objective: This study investigated how patients' knowledge, attitude, and perceptions influence their oral hygiene practices as well as peri-implant health.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Dental Plaque
- Trial name
- NCT03497065
- Testing
- non-surgical periodontal treatment
- Where
- Singapore
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Dental Plaque (Diagnosis), Dental Plaque Imaging Methods
Digital Quantification of Dental Plaque Based on Intraoral Scanner Images
This diagnostic validation study aims to develop and validate a digital method for dental biofilm quantification using three-dimensional images obtained by an intraoral scanner.
- Conditions
- Dental Plaque (Diagnosis), Dental Plaque Imaging Methods, Dental Plaque, Gingivitis
- Trial name
- NCT07152314
- Testing
- Digital plaque quantification using intraoral scanner
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Trial
This Phase II stratified randomized prevention trial will assess the efficacy of a behavioral economic theory-based financial incentive drawing program versus a control regimen to promote early childhood caries (ECC) preventive…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON (NCT03576326)
- Testing
- Drawing Incentive
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Plaque
Automated Quantification of Dental Plaque
The study generates data that contribute to the development and validation of an automated approach to full-mouth quantification of dental plaque, based on fluorescence images and intraoral scans of teeth with disclosed and…
- Trial name
- NCT06789835
- Testing
- Fluorescence imaging of disclosed and undisclosed plaque
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Orthodontic Appliance Complication
The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention
Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs).
- Trial name
- NCT04788550
- Testing
- Fluoridated toothpaste, fluoride varnish (5% sodium fluoride), CPP-ACP plus crème group
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Toothbrushing
Efficacy of Using 3D Motion Tracking Toothbrush in Dental Plaque Control
The objective of this study was to compare the efficacy of computer-assisted TBI (toothbrushing instruction) using a smart toothbrush and smart mirror (STM system) in plaque control to that of conventional TBI.
- Trial name
- NCT04627324
- Testing
- The smart toothbrush and smart mirror (STM) system (XiuSolution, Gyeonggi-do, Korea), Conventional toothbrush
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Plaque Accumulation
Water Flossing Versus Dental Floss for Oral Hygiene in Children Aged 10-15 Years: A Randomized Trial
The goal of this Randomized Clinical Trial is to compare the effectiveness of water flossing versus regular flossing in reducing dental plaque in children aged 10-15 years.
- Trial name
- NCT07469839
- Testing
- Unflavored, unwaxed regular dental floss (Oral-B, USA), Water flosser (Waterpik Cordless Plus Water Flosser, USA)
- Where
- Saudi Arabia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Plaque
Prevalence and Risk Factors of Black Tooth Stains
To assess the prevalence of black tooth stains and their relation with caries experience in the primary dentition of 3-5-year-old children.
- Trial name
- NCT05304247
- Testing
- questionnaire and clinical examination
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Mennatallah Hesham Elsayed Mohamed Ali