Clinical trials: Tooth Socket
Endodontic Issue, Periodontal Issues
Post-Extraction Healing: microRepair vs Chlorhexidine
This randomized clinical trial evaluates the efficacy of a microRepair ABX mouthwash mousse compared to 0.20% chlorhexidine in promoting wound healing following tooth extraction.
- Trial name
- NCT07555366
- Testing
- microRepair ABX Mousse, CHX mouthwash 0.20%
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Roma La Sapienza
Wound Healing, Tooth Extraction Site Healing
Effect of Injectable Platelet Rich Fibrin (i-PRF) on Extraction Socket Healing: A Split-Mouth Randomized Study.
The aim of this study is to compare extraction socket healing (SH) following surgical extraction of lower third molars (LTMs) with and without the application of injectable platelet rich fibrine (i-PRF).
- Trial name
- (i-PRF) (NCT07257328)
- Testing
- Surgical extraction of lower third molars.
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Alveolar Osteitis, Impacted Tooth
Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
The aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGFs) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars.
- Trial name
- NCT04151147
- Testing
- Concentrated Growth Factor (Test group), Non-Concentrated Growth Factor (Control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Alveolar Socket Preservation
Clinical, Histological and Micro-computed Tomographic Evaluation of Neoformed Tissue in Post-extraction Sockets Covered With Platelet-rich Fibrin (PRF) Membrane: a Randomized Controlled Trial
The platelet-rich fibrin (PRF), belongs to a new generation of plasma concentrate with biomechanical processing simplified and without the need for handling blood biochemistry.
- Trial name
- NCT02300246
- Testing
- Platelet-Rich Fibrin
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marcos de Oliveira Barceleiro
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Trial name
- BCPARPBV (NCT07638358)
- Testing
- Neobone® (Biphasic Calcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Alveolitis of Jaw, Alveoli, Teeth; Inflammation
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals.
- Conditions
- Alveolitis of Jaw, Alveoli, Teeth; Inflammation, Dry Socket, Impacted Third Molar Tooth
- Trial name
- AITS (NCT03741894)
- Testing
- Iodoform, Wound closure using sutures, Chlorhexidine
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Loss of Teeth Due to Extraction, Bone Resorption
Effect of Shock-wave Therapy on the Resorption and Bone Formation in Maxillary Postextraction Sockets
The extracorporeal shock wave therapy (ESWT) has shown good results in bones and soft tissues of the lower and upper extremities such as: pseudoarthrosis, promoting bone formation of delayed or nonunion fractures, tendinopathies…
- Trial name
- Shockwave (NCT04331028)
- Testing
- Shockwave therapy
- Where
- Spain
- Sponsor
- Rui Figueiredo
Hyaluronic Acid Gel for Preservation the Extraction Socket
Hyaluronic Acid Gel in Ridge Preservation
hyaluronic acid gel applied at the extraction socket after extraction immediately to preserve the socket from post extraction resorption. hyaluronic acid has ability for osteogenesis and new bone formation.
- Trial name
- NCT06176937
- Testing
- Hyaluronic acid, empty socket
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Alveolar Bone Resorption, Socket Preservation
Effect of Hyaluronic Acid, With Demineralized Tooth Graft, in Socket Preservation, vs Demineralized Tooth Graft Alone.
Many dentists, clinicians and researchers have conducted numerous trials, and put several materials and procedures under the test, in an attempt to preserve vertical and/or horizontal extraction sockets dimensions.
- Conditions
- Alveolar Bone Resorption, Socket Preservation, Bone Resorption, Unrestorable Dentition
- Trial name
- NCT05613075
- Testing
- tooth extraction and socket preservation with demineralized tooth graft, tooth extraction and socket preservation with demineralized tooth graft with hyaluronic acid
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unrestorable Dentition, Post-Extraction Sockets
An Assessment of Bone Augmentation in Post-Extraction Sockets
When a tooth is extracted the ridge of bone that held the tooth in place begins to heal and over time new bone grows to fill the empty space left by the missing tooth.
- Trial name
- FMD-007 (NCT00641316)
- Testing
- AtraumaticTeeth Extraction, Atraumatic Teeth Extraction/Grafted Extraction Sockets
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tooth Extraction, Socket Preservation
Injectable Alloplastic Bone Graft for Socket Preservation: Clinical, Radiographic, and Histological Evaluation
This study will evaluate the clinical efficacy of injectable alloplastic bone grafts in terms of radiography and histology in order to preserve tooth sockets following extraction.
- Trial name
- NCT07595445
- Testing
- Injectable Alloplastic Bone, natural healing (no graft)
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Tooth Extraction, Dental Implantation
Immediate Implant Placement in Fresh Extraction Sockets and Delayed Implants in Healed Sockets.
The purpose of this prospective clinical study was to compare in delayed and immediately placed implants, the marginal vertical bone loss at 4 sides of the implant (buccal, palatal, mesial and distal), as well as the buccal and…
- Conditions
- Tooth Extraction, Dental Implantation, Bone Remodeling
- Trial name
- NCT04346706
- Testing
- Extraction and Implant insertion (test), Implant insertion (control)
- Where
- Lebanon
- Volunteers
- 24 people
- Sponsor
- Saint-Joseph University
TEETH EXTRACTION
Titanium-Prepared Platelet-Rich Fibrin for Extraction Socket Healing
Alveolar ridge preservation after tooth extraction is important for maintaining bone volume and facilitating future implant placement.
- Trial name
- TPRF-SOCKET (NCT07712497)
- Testing
- Titanium-Prepared Platelet-Rich Fibrin (T-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Impacted Third Molar Tooth
Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine
Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients.
- Trial name
- NCT04349579
- Testing
- Rifamycine, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Yuzuncu Yil University
Wound Healing, Magnesium Level
Relationship Between Magnesium Depletion Score and Extraction Socket Healing
The surgical extraction of an impacted tooth is one of the most common procedures in oral surgery. Following extraction, the tissue undergoes repair and regeneration through a process known as socket healing (SH).
- Conditions
- Wound Healing, Magnesium Level, Wisdom Tooth Removal
- Trial name
- NCT06891846
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Tooth Extraction
Vestibular Socket Therapy With and Without Bone Grafting
Management of the jumping gap in the Vestibular Socket Therapy. And to study what is the best technique to manage this gap for optimal esthetic result.
- Trial name
- NCT04930497
- Testing
- vestibular socket technique with bone grafting, vestibular socket technique without bone grafting
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Hams Hamed Abdelrahman
Extracting Own Teeth
Evaluation of Bone Behavior in Maxillary Post-extractive Sites Treated With Guided Bone Regeneration (G.B.R.) Techniques in Alveolar Socket Preservation (A.S.P.) Procedures With Different Autologous and Heterologous Biomaterials.
The maxillary bone atrophies from traumatic, pathological events or related to physiological bone loss after tooth extraction, promoting a decrease in bone volume (vertical-horizontal) which has always been a crucial challenge…
- Trial name
- NCT07269990
- Testing
- compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2, Comparison of different types of biomaterials 4 months after application through the use of ASP, Comparison different types of biomaterials 4 months after application through the use of ASP
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Tooth Extraction
Combination Therapy Effect of Laser on Wound Healing and Bone Regeneration of Dental Sockets
The goal of this clinical trial is to learn if the laser works to improve wound healing and bone regeneration after tooth extraction.
- Trial name
- NCT06552936
- Testing
- Diode Laser 980 nm.
- Where
- 2 sites in Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sharif Medical Research Center
Diabetes Mellitus, Type 2, Delayed Wound Healing
Hyaluronic Acid Treatment of the Post-extraction Tooth Socket Healing in Subjects With Diabetes Mellitus Type 2
The aim of the present split-mouth study was to investigate the effect of Hyaluronic Acid (HA) in improving the post-extraction tooth socket healing in subjects with diabetes mellitus type 2.
- Conditions
- Diabetes Mellitus, Type 2, Delayed Wound Healing, Tooth Extraction Status Nos
- Trial name
- NCT05896319
- Testing
- Hyaluronic acid gel
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Turin, Italy
Surgery, Oral
Guided Bone Regeneration Using Polydioxanone (PDO) Membrane in Sockets After Tooth Extraction
The goal of this clinical trial is to compare the maintenance of socket volume in the groups treated by a resorbable regenerative membrane (Plenum® Guide) covered or not with mucous tissue, with control without treatment.
- Trial name
- NCT06015906
- Testing
- Plenum® Guide, Plenum® Oss, Tooth extraction
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- M3 Health