Clinical trials: Tooth-loss
Tooth Loss
Long- Term Follow-up of Extraction Socket Management
Twenty-nine patients needing single tooth replacement in aesthetic area were treated by extraction and socket preservation with saddle connective tissue graft between September 2009 and February 2012.
- Trial name
- NCT03410251
- Testing
- Socket preservation
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Liege
Bone Loss, Alveolar, Tooth Loss
Tooth Autotransplantation and Bone Dimension Changes
Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension.
- Conditions
- Bone Loss, Alveolar, Tooth Loss, Bone Atrophy, Alveolar
- Trial name
- NCT03927937
- Testing
- AUTOTRANSPLANTATION TOOTH
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Tooth Loss
Submerged Versus Non-Submerged Healing of Implants Subjected To Contour Augmentation
It is a randomized controlled trial to evaluate two surgical techniques for dental implant placement simultaneously with bone augmentation.
- Trial name
- NCT04559802
- Testing
- Transmucosal Technique, Submerged Technique
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Tooth Loss, Peri-implant Mucosa Defect
Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
The purpose of this non-inferiority trial is to determine the clinical efficacy of acellular dermal matrix (ADM) in the augmentation of the gum around dental implants as compared to an autologous gum graft (sCTG) obtained from…
- Trial name
- NCT02450383
- Testing
- Acellular Dermal Matrix, Autologous subepithelial connective tissue graft
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Bone Loss
Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth Socket
Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which have more than 20 teeth, are over 18 years old and require…
- Trial name
- NCT03981601
- Testing
- Lovastatin 40 MG, without drug with Bone graft
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Tooth-loss
The Use of Platelet-rich Fibrin (PRF) Membranes in Lateral Alveolar Ridge Augmentation When Jaw Bone is Missing Before Dental Implant Installation. A Study Comparing an Autogenous Bone Block Graft Covered Either by a (PRF) Membrane (Test) or Bone Substitute and a Barrier Membrane (Control)
Tooth loss can in many cases be treated with an artificial titanium root (dental implant) and subsequent manufacture of a porcelain crown.
- Trial name
- NCT04350749
- Testing
- PRF is added in the test group.
- Where
- Denmark
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dental Caries
LT Comparative Effectiveness of 2 Caries Treatments
This study is a continuation of a cluster randomized clinical trial (cRCT) conducted in 33 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio.
- Trial name
- NCT07213661
- Testing
- A "simple medical strategy" consisting of silver diamine fluoride (SDF), A "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Tooth Loss, Tooth Diseases
Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich Fibrin
Autogenous tooth transplantation (autotransplantation) represents a biologically valid alternative to implant therapy, particularly in young patients where implant placement is contraindicated due to ongoing skeletal growth.
- Conditions
- Tooth Loss, Tooth Diseases, Reimplant; Complications
- Trial name
- OpenApexT (NCT07393997)
- Testing
- Autogenous Tooth Transplantation, Alveolar Prf graft
- Where
- Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Alveolar Bone Loss, Periodontal Diseases
Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation
Tooth extraction triggers a cascade of biological events mediated by the local inflammatory response following surgical intervention and by the loss of masticatory stimulation to the periodontium.
- Conditions
- Alveolar Bone Loss, Periodontal Diseases, Periodontal Bone Loss, Periodontal Atrophy
- Trial name
- NCT07573761
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Tooth Loss, Bone Graft; Complications
Patient-reported Outcome Measures After Implant Placement With Contour Augmentation Procedure
Maintaining the general health and well-being of patients is the main goal of dental therapy. However, tooth extraction is indicated when teeth cannot be maintained in a status compatible with health, adequate esthetics…
- Conditions
- Tooth Loss, Bone Graft; Complications, Patient Satisfaction, Patient Acceptance of Health Care
- Trial name
- NCT05890170
- Testing
- Patient Reported Outcomes Measures
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bern
Immediate Implant With Bone Graft
Immediate Implant Using "Nanobone" Versus "Autogenous Bone" for Treatment of Patients With Unrestorable Single Tooth.
A successful implant therapy require appropriate hard and soft tissue, perfect implant position, appropriate alveolar ridge architecture and integration of the implant.
- Trial name
- NCT02613663
- Testing
- Immediate implants with nanobone graft, immediate implants with autogenous bone graft
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion; Displaced or Missing Teeth
Clinical and Radiological Outcomes Study on Astra Tech Osseospeed Tx Profile Implant
The Astra Tech Osseospeed Profile Implant design when placed in the healed extraction site maintains the marginal bone level
- Trial name
- NCT01510470
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hong Kong Brånemark Osseointegration Center
Single Tooth Lost, Dental Implant
Immediate and Early Single Dental Implants
The objective of the research project will be to compare immediate and early unitary implants for the rehabilitation of missing teeth in the upper aesthetic region.
- Trial name
- NCT04075383
- Testing
- immediate dental implant, immediate-delayed dental implant
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Periodontitis, Localized Aggressive, Periodontal Diseases
Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket
The aim of this study is to evaluate the accuracy of pulp test in teeth presenting with deep periodontal pocket. The null hypothesis is no significant effect of periodontitis on the accuracy of pulp test.
- Conditions
- Periodontitis, Localized Aggressive, Periodontal Diseases, Endodontic Disease, Endodontic Inflammation
- Trial name
- NCT04399135
- Testing
- Orthopantomogram X-ray view, Endo-Ice, Electric Pulp Tester (EPT)
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qassim University
Alveolar Bone Loss
mp3 vs Apatos in Post-extractive Sockets
The primary aim of the present multicenter randomized controlled trial was to evaluate and compare the shortterm clinical and histological changes of extraction sockets after ridge preservation procedures with changes of…
- Trial name
- NCT02644070
- Testing
- alveolar bone preservation with mp3, alveolar bone preservation with apatos, stabilization with membrane
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tuscan Dental Institute
Tooth Loss
Ridge Preservation With Putty Allografts
The study will consist of randomized controlled clinical study trial comparing the results of a demineralized putty allorgraft versus a combined mineralized/demineralized putty allograft in approximately 30 patients, 15 per…
- Trial name
- NCT03956251
- Testing
- Combined Mineralized/Demineralized Putty Allograft, Demineralized Putty Allograft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Dental Implants
Variable-thread Versus Standard Dental Implants for Replacing Missing Teeth
Background and objectives: Primary and secondary implant stability remain the most relevant and reliable clinical indicator for long-term survival of dental implants.
- Trial name
- NCT06808854
- Testing
- Dental implant treatment (variable-thread implants), Dental implant treatment (standard implants)
- Where
- United Arab Emirates
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Tooth Loss
Hard and Soft Tissue Maintenance Around Implants With a Sloped Configuration
This study is a controlled, randomized clinical trial over about 16-months (active phase). 40 patients in need of replacement of a single tooth with a minimal crestal bone width of 4 - 5mm and suitable for simultaneous GBR…
- Trial name
- NCT04712565
- Testing
- Astra Tech Implant System Profile EV, Astra Tech Implant System EV
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Dental Atraumatic Restorative Treatment
Clinical Evaluation of Enamel Microhardness Using Tooth Whitening Agents
The investigator will review the medical history taken by the participants' orthodontist that determined participants eligibility to participate in this study on the first appointment.
- Trial name
- NCT07165366
- Testing
- Carbamide Peroxide 10%, Hydrogen Peroxide
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ultradent Products, Inc.
Tooth Loss
Removable Partial Dentures Made of PEEK
As part of the clinical study, 25 patients each were provided with removable partial dentures with clasps made of PEEK in two centres (University Hospital Heidelberg, Department of Prosthodontics and University Hospital for…
- Trial name
- KLAP (NCT06191107)
- Testing
- Removable Partial Denture
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg