Clinical trials: Tooth-loss
Microbial Colonization, Missing Teeth
Effect of Crown Material on Gingival Microbial Colonization
Prior approval from SOD ethical committee has been received. All patients presenting to the General OPD of School of Dentistry, Islamabad will be screened.
- Trial name
- NCT07083102
- Testing
- Experimental
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Bone Loss, Alveolar, Tooth Loss
Tooth Autotransplantation and Bone Dimension Changes
Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension.
- Conditions
- Bone Loss, Alveolar, Tooth Loss, Bone Atrophy, Alveolar
- Trial name
- NCT03927937
- Testing
- AUTOTRANSPLANTATION TOOTH
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingival Recession, Localized, Sensitivity, Tooth
Two Different Graft Harvesting Techniques Applied in Localized Gingival Recessions
The primary purpose of this study is to compare the root coverage rate of the gingival unit-shaped connective tissue graft, obtained by intraoral de-epithelization, with the traditional de-epithelialized free gingival graft in…
- Conditions
- Gingival Recession, Localized, Sensitivity, Tooth, Attachment Loss, Periodontal
- Trial name
- NCT05923294
- Testing
- Coronally advanced flap with connective tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Tooth Loss
Hard and Soft Tissue Maintenance Around Implants With a Sloped Configuration
This study is a controlled, randomized clinical trial over about 16-months (active phase). 40 patients in need of replacement of a single tooth with a minimal crestal bone width of 4 - 5mm and suitable for simultaneous GBR…
- Trial name
- NCT04712565
- Testing
- Astra Tech Implant System Profile EV, Astra Tech Implant System EV
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Tooth-loss, Edentulous Mouth
Complete Lower Dentures on 1 or 2 Implants
This study is a randomized clinical trial to compare patient satisfaction and prosthetic outcomes with lower dentures retained by one or two implants.
- Conditions
- Tooth-loss, Edentulous Mouth, Complete Denture, Complete Lower Denture
- Trial name
- NCT02117856
- Testing
- 1 implant placed surgically in the mandibular midline, 2 implants placed surgically in the mandibular canine sites, Soft reline (Coe Comfort) of the existing complete lower denture
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Alveolar Bone Loss, Sinus Floor Augmentation
Impact of Alveolar Ridge Preservation on the Potential Need for Sinus Floor Elevation: A 10-year Retrospective Radiographical Study
This research aims to investigate the influence of alveolar ridge preservation, after extraction of maxillary posterior teeth, on the potential need of sinus floor augmentation procedures (that include lateral or crestal sinus…
- Conditions
- Alveolar Bone Loss, Sinus Floor Augmentation, Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- NCT07526129
- Testing
- Alveolar ridge preservation using bony biomaterials
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Posterior Mandible Missing Tooth and /or Teeth
Flapless Versus Flap Technique for Evaluation of Crestal Bone Loss and Osseointegration of Dental Implants
this study aimed to evaluate both clinically and radiographically the effect of flapless versus flap techniques on initial crestal bone loss and osseointegration of dental implants in lower posterior area.
- Trial name
- NCT07159529
- Testing
- flapless technique, flap technique, tissue punching
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Periodontal Diseases, Tooth Loss
Effect of Periodontal Maintenance Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-Smokers: A Cohort Retrospective Analysis With a Follow-up Up to 40 Years
Periodontal diseases are infections cause by dental plaque (Socransky, 1970). Risk factors are present which modify the course of disease progression.
- Conditions
- Periodontal Diseases, Tooth Loss, Compliance, Smoking
- Trial name
- NCT04938089
- Testing
- Maintenance
- Where
- Lebanon
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Tooth Loss
Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins
Ultrasound activated pins have been used for the promotion of bone healing in combination with biodegradable membranes during bone grafting procedures.
- Trial name
- NCT02449707
- Testing
- Lateral Window Technique Augmentation for Maxillary Sinus, Ultrasound activated resorbable poly-D-L-lactide pins, Purus® Cancellous Allograft
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Missing Teeth
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
- Trial name
- NCT05403099
- Testing
- Hyaluronic acid, conventional implant placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Space Maintenance, Tooth Loss / Rehabilitation
3D-Printed Versus Band-and-Loop Versus Denovo Space Maintainers in Primary Dentition.
Purpose of the Study When a child loses a "baby" molar early due to a cavity or injury, the surrounding teeth can shift into the empty space. This often blocks the permanent adult tooth from growing in correctly.
- Trial name
- NCT07613658
- Testing
- 3D-Printed Custom Space Maintainer, Conventional Band-and-Loop Space Maintainer, Denovo Chairside Space Maintainer
- Where
- Saudi Arabia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Murad Alrashidi
Jaw, Edentulous, Partially
Evaluation of Marginal Bone Loss and Associated Factors Around Ziacom Dental Implants With Different Prosthetic Connection
Dental implants may suffer from bone loss around them, particularly at the upper portion where the prosthesis starts. The connection between both parts of the tooth restoration is key for avoiding micromovement during chewing…
- Trial name
- NCT05859113
- Testing
- Ziacom Galaxy dental implant with internal connical prosthetic connection, Ziacom Zinic dental implant with internal hexagonal prosthetic connection
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Tooth Loss, Bone Graft; Complications
Patient-reported Outcome Measures After Implant Placement With Contour Augmentation Procedure
Maintaining the general health and well-being of patients is the main goal of dental therapy. However, tooth extraction is indicated when teeth cannot be maintained in a status compatible with health, adequate esthetics…
- Conditions
- Tooth Loss, Bone Graft; Complications, Patient Satisfaction, Patient Acceptance of Health Care
- Trial name
- NCT05890170
- Testing
- Patient Reported Outcomes Measures
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bern
Immediate Implant With Bone Graft
Immediate Implant Using "Nanobone" Versus "Autogenous Bone" for Treatment of Patients With Unrestorable Single Tooth.
A successful implant therapy require appropriate hard and soft tissue, perfect implant position, appropriate alveolar ridge architecture and integration of the implant.
- Trial name
- NCT02613663
- Testing
- Immediate implants with nanobone graft, immediate implants with autogenous bone graft
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Missing Teeth
Osseodensification and Implant Survival and Success
Approximately 40 implants from patients seeking treatment at the University of Oklahoma, College of Dentistry will be recruited for this study.
- Trial name
- NCT04741594
- Testing
- Densah
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tooth Loss
Implant-Abutment Interface Design on Bone and Soft Tissue Levels Around Implants Placed Using Different Transcrestal Sinus Floor Elevation
Sixty patients with partially edentulous posterior maxilla requiring a transcrestal sinus floor elevation technique to insert one implant will be selected.
- Trial name
- NCT02953392
- Testing
- Anorganic Bovine Bone Graft Material, Collagen Membrane, Shelta Platform Switching Premium Implants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Periodontal Bone Loss
Effect of Orthodontic Treatment on Periodontally Compromised Dentition- Randomised Control Trial
The main aim of this prospective, randomized controlled clinical study is to: To evaluate and compare the effect of a combined orthodontic -periodontal treatment protocol versus periodontal treatment alone on osseous and non…
- Trial name
- NCT03914339
- Testing
- Periodontal and orthodontic treatment, periodontal treatment
- Where
- 2 sites in India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Jaw, Edentulous, Edentulism, Complete
Tri-Lobe vs. Hexagonal Connections in Immediately Loaded Mandibular Overdentures
Objective: Compare changes in crestal bone height and peri-implant bone density using cone-beam computed tomography (CBCT) at baseline, 6 months, and 12 months post-placement.
- Conditions
- Jaw, Edentulous, Edentulism, Complete, Peri-implant Bone Loss
- Trial name
- NCT07824219
- Testing
- ReActive Implant System (Internal Tri-Lobe Platform), Legacy II Implant System (Internal Hexagonal Platform)
- Where
- United Arab Emirates
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Tooth Avulsion, Tooth Crown Fracture
Therapeutic Wavelength Nanotechnology Devices in Alveolar Preservation
After tooth extraction, a progressive alveolar bone resorption is observed. Alveolar ridge preservation consists of placing a biomaterial within the extraction socket and covering it with a membrane.
- Trial name
- APnanotecnolog (NCT07371130)
- Testing
- Socket Preservation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro