Clinical trials: Total Hip Surgery
Total Hip Replacement, Thromboelastometry
Impact of Surgical Injury on Haemostatic Tests in Patients Undergoing Total Hip Replacement With Subgroup Analysis of Patients With Neoplasm
Total hip replacement (THR) is associated with extensive tissue injury and considerable blood loss that can be complicated by hyperfibrinolysis with an increased need for blood transfusion.
- Conditions
- Total Hip Replacement, Thromboelastometry, Bone Neoplasm of Hip
- Trial name
- I-SIGHT-THR (NCT04442373)
- Testing
- Rotational thromboelastometry
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Tranexamic Acid, Blood Loss, Surgical
Intravenous vs. Topical Tranexamic Acid in Revision THA (VITALITY-X)
The objective of this study is to evaluate and compare the effects of intravenous and topical administration of tranexamic acid during revision hip arthroplasty on blood loss, allogenic blood transfusion rates, length of hospital…
- Conditions
- Tranexamic Acid, Blood Loss, Surgical, Arthroplasty, Replacement, Hip
- Trial name
- VITALITY-X (NCT02938962)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Hip Prosthesis Infection
Single-stage Surgery With Antibiotic-loaded Hydrogel Coated Implants Versus Two Stage Surgery for Secondary Prevention of Complex Chronic Periprosthetic Hip Joint Infection
Each year, around 1500 infected Total Hip Arthroplasties (THA) need non-conservative surgery, remaining an issue for patients and healthcare units.
- Trial name
- SINBIOSE-H (NCT04251377)
- Testing
- Defensive Antiadhesive Coating DAC®, Novagenit SRL
- Where
- 14 sites in France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Arthritis, Avascular Necrosis
A Comparison of Two Different Surgical Techniques for Total Hip Resurfacing
This study compares the posterior approach to the anterolateral approach using the ReCap® Total Hip Resurfacing System.
- Trial name
- NCT00750984
- Testing
- Anterolateral approach, Posterior approach, ReCap Total Hip Resurfacing
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip, Osteoarthritis, Knee
Study on Costs and Effects of Waiting Time in Total Hip and Knee Replacements
The aim of this study is to compare the cost-effectiveness of major joint replacement in patients with short and non-fixed (control group) waiting time (WT).
- Trial name
- NCT00294424
- Testing
- Short waiting time, Non-fixed waiting time
- Where
- Finland
- Volunteers
- 833 people
- Sponsor
- Academy of Finland
Hip, Osteoarthritis
Comparison of Functional Outcome in Patients After Hip Arthroplasty Depending on Surgical Approach
The aim of the study will be to compare functional outcomes of the two surgical hip approaches in total hip arthroplasty: anterior, posterolateral and anterolateral.
- Trial name
- NCT03850665
- Testing
- Direct Anterior Approach (DAA), Anterolateral approach
- Where
- 2 sites in Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Warsaw
Hip Arthroplasty, Total, Prevention of Venous Thromboembolism
ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty
Surgical hip replacement (total hip arthroplasty, THA) is associated with a high risk of venous thromboembolism, but the appropriate duration of postoperative medical thromboprophylaxis ("anticoagulation") remains highly…
- Trial name
- ENABLE-Hip (NCT06611319)
- Testing
- Prevention of Venous Thromboembolism
- Where
- 6 sites in Austria, Germany
- Volunteers
- 2,932 people
- Sponsor
- Prof. Stavros Konstantinides, MD
Osteoarthritis, Avascular Necrosis
Fitmore Hip Stem PMCF Study: A Multi-centre, Non-comparative, Prospective Post-market Clinical Follow-up Study.
A multi-centre, non-comparative, prospective post-market clinical follow-up study to obtain survival, clinical and radiographic outcomes data on the Zimmer Fitmore Hip Stem.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Prosthesis Failure
- Trial name
- NCT03411044
- Testing
- Fitmore Hip Stem
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 420 people
- Sponsor
- Zimmer Biomet
Empowerment
The Effects of Using the Empowerment Model Intervention in Primary Total Hip Replacement Surgery Elders
Degenerative arthritis is a common and serious chronic illness that impacts the quality of life of older adults. Knowledge about the effects of empowerment education program in older adults with total hip replacement surgery are…
- Trial name
- NCT02815163
- Testing
- Empowerment education
- Volunteers
- 108 people
- Sponsor
- Tzu-Ting Huang
Osteoarthritis of the Hip
Efficacy of Preoperative Education and Mini-invasive Surgery for Total Hip Replacement
We propose to evaluate a preoperative education of the patient and a new surgical technique (the mini-invasive THR) that could reduce the time to achieve functional independence.
- Trial name
- ANRACT (NCT00449228)
- Testing
- -preoperative education and total hip replacement
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thrombosis, Venous
Total Hip Replacement Study Of GSK576428 (Fondaparinux Sodium)
This study is requested by PMDA to confirm the optimal dose for THR (total hip replacement).
- Trial name
- NCT00320398
- Testing
- Fondaparinux
- Volunteers
- 114 people
- Sponsor
- GlaxoSmithKline
Perioperative/Postoperative Complications, Hypovolemia
Goal-directed Therapy in High-risk Surgery
There is growing evidence that the risk of postoperative complications can be decreased by optimizing the amount and type of infusion fluids given during surgery, steered by goal-directed therapy based on flow-related hemodynamic…
- Conditions
- Perioperative/Postoperative Complications, Hypovolemia, Hypoxia
- Trial name
- NCT01681238
- Testing
- Protocol group 2, Protocol group 1
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Guangzhou First People's Hospital
Total Knee-replacement, Total Hip-replacement
Clinical Trial for Fibrin Sealant in Knee Surgery
Thermogenesis is a company that sells a machine for the production of fibrin sealant of single donor plasma, the CryoSeal Fibrin Sealant System (CS-1). Fibrin sealant consists of two components: cryoprecipitate and thrombin.
- Trial name
- NCT00440921
- Testing
- Single donor Allogenous Fibrin Sealant
- Sponsor
- Sanquin Research & Blood Bank Divisions
Anesthesia
Audiovisual Distraction for Patients Undergoing Total Knee or Hip Replacement Surgery
The primary purpose of this study is to investigate whether audiovisual distraction can lead to a reduction in standard of care administered intraoperative propofol consumption compared to those who receive propofol sedation…
- Trial name
- NCT03191838
- Testing
- Audiovisual Distraction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Evaluate Surgical, Medical and Pharmacological Factors Influence on Wound Healing Following Primary Arthroplasty Surgery
Identification of Risk Factors of Prolonged Wound Healing Following Primary Arthroplasty
Prolonged wound drainage following total joint replacement surgery has been shown to be a predictor of postoperative infection. Several factors have been associated with delayed wound healing and increased risk of infection.
- Trial name
- NCT01477047
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Hvidovre University Hospital
Hip Arthropathy, Postoperative Pain
Pericapsular Nerve Group Block for Total Hip Arthroplasty
Controlling pain after hip replacement surgery improves comfort and partient satisfaction. Pain after hip replacement has traditionally been managed using systemic pain medications including acetaminophen and non-steroidal…
- Trial name
- NCT04295408
- Testing
- Pericapsular nerve group block with saline solution, Pericapsular nerve group block with ropivacaine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Pain, Postoperative
The PENG Block in Elective Hip Surgery and Its Effect on Postoperative Pain and Length of Stay.
Effective postoperative pain management in elective hip surgery is crucial for the patients well-being, rapid mobilisation and potential reduction of length of stay.
- Trial name
- NCT05056675
- Testing
- PENG block
- Where
- Switzerland
- Volunteers
- 151 people
- Sponsor
- Hôpital Fribourgeois
Compare Two Surgical Approaches Used in Total Hip Arthroplasty
Short-term Results of SuperPATH Versus Direct Lateral Approach In Primary Total Hip Arthroplasty: A Randomized Controlled Study.
Total hip arthroplasty (THA) has shown great success in relieving joint pain and disability and has been a procedure of choice for the treatment of end-stage degenerative joint diseases and trauma.
- Trial name
- NCT07633925
- Testing
- Surgical approaches: direct lateral approach for the hip and SuperPATH approach
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Deep Vein Thrombosis, Total Hip Prosthesis
Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs
The numerical ratio between the value of the thrombin generation test performed without soluble thrombomodulin and the value of the thrombin generation test performed in the presence of soluble thrombomodulin, performed…
- Conditions
- Deep Vein Thrombosis, Total Hip Prosthesis, Knee Prosthesis
- Trial name
- GT-PT (NCT03634124)
- Testing
- Blood test, Doppler ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Total Hip Arthroplasty, Hip Arthrosis
Tissue Sparing Surgery in Total Hip Arthroplasty
Rationale of the study is to evaluate through a prospective randomized controlled study if a modified direct superior posterolateral approach (sperimental approach) to the hip articulation which entirely spares i.e.
- Trial name
- NCT04358250
- Testing
- Direct Superior Approach, posterolateral approach
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio