Clinical trials: Total Knee Arthroplasty Recovery
Knee Osteoarthritis (OA), Artrosis of the Knee
PROPRIOCEPTION, KINESIOPHOBIA AND FUNCTIONAL RECOVERY AFTER GONARTHROSIS SURGERY
This observational study aims to investigate the relationships between proprioception, causes of kinesiophobia, sensory processing characteristics, and functional recovery in individuals undergoing gonarthrosis surgery.
- Trial name
- NCT07480473
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Medipol University
Revision Total Knee Arthroplasty
Adductor Canal Block (ACB) vs Femoral Nerve Block (FNB) in Revision Total Knee Arthroplasty
This is a prospective, randomized, blinded study with a parallel design and an allocation ratio of 1:1 for the treatment groups.
- Trial name
- NCT03697538
- Testing
- Nerve Block for pain control post-revision total knee arthroplasty
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pennsylvania
PACU Stay After THA Under Spinal Anaesthesia, PACU Stay After TKA Under Spinal Anaesthesia
Recovery at the Post Anaesthetic Care Unit After Hip and Knee Arthroplasty
To clarify patient related problems in the Post Anaesthetic Care Unit (PACU) immediately after fast-track hip and knee arthroplasty.
- Trial name
- NCT01178489
- Where
- Denmark
- Volunteers
- 170 people
- Sponsor
- Hvidovre University Hospital
Arthroplasty, Replacement, Knee
Testing Regional Anesthesia Techniques for Up and Early Discharge Following Knee Arthroplasty - A Feasibility Study
To assess feasibility of a a trial investigation postoperative patient-reported quality of recovery after total knee arthroplasty (TKA) with periarticular joint injection (PAI) ± single shot adductor canal block with or without…
- Trial name
- TRUE KnORTH 2 (NCT06054750)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Sponsor
- McMaster University
Osteoarthritis, Knee
Outcome Comparison of Two Total Knee Arthroplasty Systems: e.Motion-Pro Versus Genesis II
Recently, E.Motion-PS-Pro (B.Braun-Aesculap, Tuttlingen, Germany), a new mobile bearing knee system with a unique ball and socket post-cam mechanism was developed for use in total knee arthroplasty.
- Trial name
- NCT02276118
- Testing
- device: e.motion PS Pro, device : Genesis II
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Osteoarthritis, Knee
Does Rehabilitation After Total Knee Arthroplasty Work? - Feasibility Trial
The aim of this feasibility trial is to investigate the feasibility of a trial intervention for a population of patients after total knee replacement for osteoarthritis.
- Trial name
- DRAW-TKA-Fea (NCT05935020)
- Testing
- Usual care - Municipal exercise-based rehabilitation, Return to Everyday life, Symptom guide and encouragement to follow DHA/WHO recommendations for physical activity
- Where
- 2 sites in Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Osteo Arthritis Knee, Knee Arthroplasty
Effects of Motor Imagery Intervention on Functional Recovery Following Total Knee Arthroplasty
The knee osteoarthritis becoming a leading cause of disability among older adults' population. When conventional treatments fail, a total knee arthroplasty (TKA) is suggested.
- Trial name
- KSV2017 (NCT03684148)
- Testing
- Motor imagery practice
- Where
- Slovenia
- Volunteers
- 34 people
- Sponsor
- Science and Research Centre Koper
Arthropathy of Knee Joint
Total Knee Arthroplasty - Accelerated Recovery Without Tourniquet
Introduction: Approximately 7000 total knee replacements (TKAs) are done every year. More than 90% of these knee replacements are performed with the use of bone cement.
- Trial name
- NCT01309035
- Testing
- Total Knee Arthroplasty
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Postoperative Recovery, Total Knee Arthroplasty
Nutrition and Swelling
This study is looking at whether taking a nutritional supplement before and after knee replacement surgery affects normal recovery.
- Trial name
- NCT07899762
- Testing
- Xcelerated Recovery Nutritional Supplement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Arthroplasty Complications
Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program
The objectives are to describe the transition from traditional care to an enhanced recovery program for the management of total knee arthroplasty, and to evaluate the effect on patient outcomes.
- Trial name
- NCT05028426
- Testing
- Enhanced recovery program
- Where
- France
- Volunteers
- 455 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Pain
Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty
Study will evaluate the effect of liposomal bupivacaine versus standard bupivacaine on physical therapy measures and pain scores as well as opiate consumption.
- Trial name
- NCT03182933
- Testing
- Peripheral Nerve Blockade, 10 meter walk test on post-operative day 1, In person and over the phone questionnaire
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Wisconsin, Madison
Total Knee Anthroplasty, Total Knee Arthroplasty Recovery
The Effects of Mir Shakeel Teleintegrated Therapy Plan in Patients Undergoing Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effectiveness of a newly developed Modified Structured Telerehabilitation Intervention Protocol (MSTITP) compared with conventional in-person physical therapy in patients…
- Trial name
- RCT (NCT07239258)
- Testing
- Mir Shakeel Teleintegrated Therapy plan, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Lincoln University College Malaysia
Total Knee Arthroplasty Recovery, Knee Osteoarthritis
Wearable Knee-Assisted Rehabilitation for Range of Motion and Muscle Strength After Total Knee Arthroplasty
This randomized controlled trial evaluates a wearable electrogoniometry-based telerehabilitation system designed to support recovery after total knee arthroplasty.
- Trial name
- NCT07875725
- Testing
- ReBK Wearable Telerehabilitation System, Standard Home-Based Rehabilitation
- Where
- 3 sites in Chile
- Volunteers
- 80 people
- Sponsor
- University of Chile
Non-inflammatory Degenerative Joint Disease
Evaluation of Post-Operative Recovery in ATTUNE® Total Knee Arthroplasty
This post-marketing investigation will evaluate the rate of recovery of the ATTUNE knee from the time of surgery through the 6 month endpoint in patients with severely painful and/or severely disabling Non-inflammatory…
- Trial name
- NCT02339610
- Testing
- ATTUNE Primary, Cemented Total Knee Replacement
- Where
- 4 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- DePuy Orthopaedics
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered (IPSA) Block vs. Local Infiltration Analgesia in Knee Replacement Surgery
The study aims to test the safety and effectiveness of two different surgeon-administered methods of the anesthesia medication EXPAREL during knee replacement surgery.
- Trial name
- CRS-121 (NCT07584915)
- Testing
- Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA, Local Infiltration Analgesia (LIA), Bupivacaine liposome injectable suspension (IPSA block)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Arthroplasty, Replacement, Knee, Pain, Postoperative
Continuous Adductor Canal Infusion vs. Single-injection Adductor Canal Block for Total Knee Arthroplasty
Multimodal analgesia (MMA) has been endorsed to improve postoperative analgesia and functional activity after surgery, and integrating regional analgesia to reduce the consumption of opioid has also been used in postoperative…
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Multimodal Analgesia
- Trial name
- NCT05669898
- Testing
- Pain scores (numerical rating scale at rest and motion): will be assessed with numerical rating scale at both rest and motion on both knees., Brief Pain Inventory (Short Form), WOMAC Osteoarthritis index, and Lower extremity functional scale, Rehabilitation physiotherapy
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
OA Knee, TKA
Comparison of Functional Recovery Between Restricted Inverse Kinematic Alignment and Adjusted Mechanical Alignment With Robotic-assisted Unilateral Total Knee Arthroplasty.
The goal of this clinical trial is to learn if restricted inverse kinematic alignment total knee arthroplasty (restricted iKA TKA) improves functional recovery compared to adjusted mechanical alignment total knee arthroplasty…
- Trial name
- NCT06835621
- Testing
- Restricted inverse kinematic alignment Total Knee Arthroplasty, Adjusted Mechanical alignment Total Knee Arthroplasty
- Where
- 2 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University
Osteoarthritis
Home PT vs FORCE PT
The purpose of this study is to determine if unsupervised, home rehabilitation delivered by a web-based platform or paper manual is a safe and effective alternative to outpatient physical therapy after total knee replacement.
- Trial name
- NCT02911389
- Testing
- Home PT via web-based platform, Home PT via paper manual, outpatient PT
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Arthropathy of Knee, Arthropathy of Hip
Results of the Application of the Clinical Pathway of Intensified Recovery Surgery for Adults in the Processes of Total Knee and Hip Replacement at the Maz Hospital
The investigators are going to study all the patients who have undergone surgery at the MAZ hospital from 2019 to the present for knee replacement and hip replacement.
- Trial name
- NCT05338255
- Where
- Spain
- Volunteers
- 534 people
- Sponsor
- Universidad de Zaragoza
Knee Replacement Arthroplasty
IPACK Study in Total Knee Arthroplasty Patients
This study proposes to compare current multimodal analgesic treatment for TKA with a new multimodal analgesic regimen to demonstrate decreased opioid requirement, time to rehabilitation, and time to reach hospital discharge.
- Trial name
- NCT03954379
- Testing
- Standard of Care (ACB, SA, peri-op pain management), IPACK and multi-modal analgesic regimen, Periarticular Local Anesthetic Infiltration
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto