Clinical trials: Tourniquet
Trauma Injury, Hemorrhage
Tourniquet Training Effectiveness Study
Trauma is the leading cause of death for individuals ages 1-45 years old, within this cohort, and uncontrolled hemorrhage is the leading cause of preventable death.1,2 Tourniquets have been shown to be effective in dramatically…
- Trial name
- TRIAGE (NCT03538379)
- Testing
- Bleeding Control Basic (B-Con) Course
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Nerve Compression
Neurologic Examination of Wide and Narrow Tourniquets
Nerve injury is a serious potential complication associated with the clinical use of exsanguinating tourniquets in surgery. Recently, a novel narrow tourniquet has been proposed, with the claim that it may cause less compression…
- Trial name
- HEM (NCT02023476)
- Testing
- MRI
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hand Surgery
Music in Wide Awake Hand Surgery
Wide awake local anesthesia no tourniquet (WALANT) surgery has emerged as a popular technique in hand surgery over the last decade.
- Trial name
- NCT04636463
- Testing
- Intraoperative Music
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Limb Occlusion Pressure
Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery
Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain.
- Trial name
- LOP (NCT04390425)
- Testing
- Experimental - Limb Occlusion pressure
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Radius Fracture Distal
WALANT in Distal Radius Fracture Osteosynthesis
The purpose of this study is to assess the applicability and potential benefits of Wide Awake Local Anesthesia No Tourniquet (WALANT) or Local Anesthesia No Tourniquet ("LANT) versus locoregional anesthesia (LRA) and tourniquet…
- Trial name
- NCT05421000
- Testing
- WALANT, Locoregional anesthesia and tourniquet
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital Arnau de Vilanova
Arthritis Knee, Blood Loss
Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA
Tourniquet application in total knee arthroplasty has many benefits and might have a role in the incidence of peri-operative complications the aim of this research: is to look into the effectiveness of the limited application of…
- Conditions
- Arthritis Knee, Blood Loss, Arthroplasty Complications
- Trial name
- NCT05691751
- Testing
- primary unilateral total knee arthroplasty with limited application of tourniquet, primary unilateral total knee arthroplasty with full application of tourniquet
- Where
- Syria
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Damascus University
Osteoarthritis, Knee
Efficacy Testing of Different Tourniquet Pressure Used for Postoperative Pain Reduction in Total Knee Arthroplasty
Tourniquet use during total knee replacement (TKR) improves visibility, significantly decreases intra-operative blood loss and reduce operative time.
- Trial name
- NCT03931837
- Testing
- Tourniquet: Systolic blood pressure + 75 mmHg, Tourniquet: Systolic blood pressure + 100 mmHg, Tourniquet: Systolic blood pressure + 150 mmHg
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Hemorrhage
Comparison of 4 Tactical Tourniquets Used in War Medicine
Bleeding remains the leading cause of death in combat, and the literature suggests that tourniquetable hemorrhage is the second leading cause of preventable death, behind non- tourniquetable hemorrhage.
- Trial name
- NCT04870814
- Testing
- Tactical tourniquet set up, Medical ultrasound, Questionnaire
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hand Injuries/Disease Requiring Surgery to the Hand
A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain
Hand surgery requires a reduced blood flow to the hand during the operation, which is achieved using a tourniquet (tightly inflated circumferential cuff) around the upper arm. However this tourniquet is painful.
- Trial name
- ReTAP (NCT01611064)
- Testing
- Oxygen, Medical air
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Ischemia/Reperfusion Injury
Effects of Sevoflurane in Subanesthetic Concentrations on the Forearm Perfusion
Sevoflurane preconditioning and cardiovascular protection against ischemia/reperfusion injury. Study hypothesis: The volatile anesthetic sevoflurane at subanesthetic concentrations achieves endothelial protection against…
- Trial name
- NCT00526695
- Testing
- Sevoflurane (Preconditioning)
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hemorrhage
Retention of Tourniquet Application Skills Following Participation in a Bleeding Control Course
Prospective, observational study of students 6 months after completing a Stop the Bleed course to determine overall ability to effectively use a tourniquet to stop external extremity hemorrhage.
- Trial name
- NCT03762863
- Testing
- Tourniquet application skill retention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Somerville Office of Emergency Management
Knee Replacement
Total Knee Replacement With Tourniquet or Aquamantys
The purpose of this study is to compare quadriceps muscle strength, pain, opioid consumption and patient function during the first three months after short-stay total knee replacement between patients treated with short-duration…
- Trial name
- NCT04016285
- Testing
- Aquamantys, Tourniquet
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Stephen Duncan
Hand Surgery, Local Infiltration
Wide-Awake Local Anesthesia No Tourniquet (WALANT) With Versus Without Hyaluronidase for Hand Surgery
The WALANT (Wide Awake Local Anesthesia No Tourniquet) method, introduced by Dr. Donald H. Lalonde over a decade ago, has gained popularity due to its favorable outcomes and patient satisfaction.
- Trial name
- NCT07000058
- Testing
- Hyaluronidase and Lidocaine 1% mixture, lidocaine 1 % mixture
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Safety Issues, Post Operative Pain
Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery
Safety and efficacy of wide awake local anesthesia no torniquet technique (WALANT) in ankle surgery. Studying risks and benefits from WALANT compared to general anesthesia .
- Conditions
- Safety Issues, Post Operative Pain, Local Anesthetic Complication
- Trial name
- NCT05864664
- Testing
- Wide awake local anaesthesia no tourniquet technique
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ali Lari
Osteoarthritis, RA
Surgical Tourniquets and Cerebral Emboli
BACKGROUND In 2012 76,497 primary total knee (TKR) replacements were performed in England, Wales and Northern Ireland . Traditionally TKR surgery is undertaken with the aid of a surgical tourniquet.
- Conditions
- Osteoarthritis, RA, Trauma
- Trial name
- NCT02240732
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Trauma Injury, Hemorrhage Wound
Assessment of Automatic Tourniquets for Soldiers During Wartime
The goal of this clinical trial is to compare usability and performance of automatic tourniquets (AUT) and standard mechanical tourniquets (CAT) in healthy adults.
- Trial name
- NCT06123104
- Testing
- Occlusion of blood flow diagnosed by Point of Care UltraSound (POCUS)
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Superficial Forearm Veins Compressibility and Width
Effect of Double Tourniquet Technique on Ultrasonographic View of Forearm Veins
Vein compressibility will be assessed after light pressure applied with the ultrasound probe. Vein compressibility will be graded as 3 (100% compressed), 2 (50-100 compressed), and 1 (less than 50% compressed).
- Trial name
- NCT04613011
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bahaa Mohammed Refaie
Arthroplasty, Replacement, Knee, Acute Kidney Injury
After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet
This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial
- Conditions
- Arthroplasty, Replacement, Knee, Acute Kidney Injury, Tourniquets, Knee Osteoarthritis
- Trial name
- NCT03795805
- Testing
- total knee arthroplasty, Tourniquet limb cuff, Intaarticular lidocain
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Tourniquet Hypertension, Intraoperative Hypertension
Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension
The purpose of this prospective randomized double-blind study is to determine if the novel technique of ultrasound guided peri-arterial injection of local anesthetic around the femoral artery decreases ischemic hypertension…
- Conditions
- Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
- Trial name
- NCT03390426
- Testing
- Mepivacaine, Perifemoral Injection of Local Anesthetic, Saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences