Clinical trials: Tourniquets
Arthropathy of Knee, Spinal Anesthesia
Dexmedetomidine on Tourniquet Induced -Systemic Effects
Eighty patients were randomly assigned to either control (CON) or dexmedetomidine (DEX) group. DEX group received a loading dose of 0.5 µg/ kg of intravenous dexmedetomidine over 10 minutes, followed by a continuous infusion of…
- Conditions
- Arthropathy of Knee, Spinal Anesthesia, Tourniquet, Ischemia-reperfusion Injury
- Trial name
- NCT04307290
- Testing
- Dexmedetomidine Hydrochloride, or Saline
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Wonkwang University Hospital
Vascular Injury
Survey of Tourniquet Use in a Combat Support Hospital
Data will be collected on the type of tourniquet and circumstances of its use. Patients with penetrating extremity injury will have clinical and pre-clinical hospital data collected.
- Trial name
- NCT00517166
- Testing
- CAT (Combat Arms Tourniquet)
- Where
- Iraq
- Volunteers
- 584 people
- Sponsor
- United States Army Institute of Surgical Research
Tourniquet-induced Pain, Procedural Pain
Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia.
- Trial name
- NCT07878962
- Testing
- Dexmedetomidine, ketorolac, Lidocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Mayo Hospital Lahore
Hemorrhage
Performance of Junctional Tourniquets in Normal Human Volunteers
Normal human adult volunteers wereused to investigate the performance of medical devices intended to stop junctional bleeding on the battlefield.
- Trial name
- NCT01965561
- Testing
- CRoC, AAJT, JETT
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Institute of Surgical Research
Muscles Ischemia
Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty
Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty: WOMAC-Score Knee-Score Radiographic Evaluations and Scoring System Biochemical muscle biopsy analysis
- Trial name
- NCT02475603
- Testing
- Total knee arthroplasty
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Carpal Tunnel Syndrome
Novel Decision Aid for Carpal Tunnel Patients
A questionnaire will be given to patients who are considering undergoing hand surgery as a treatment for Carpal Tunnel Syndrome to help participants decide between two surgical options- Wide-Awake-Local-Anesthesia-no-Tourniquet…
- Trial name
- NCT04693273
- Testing
- Decision Aid for Surgical Modality Choice
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Carpal Tunnel Syndrome
aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)
Introduction Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome in Finland and worldwide. Nowadays carpal tunnel release (CTR) surgery is often done in local anaesthesia.
- Trial name
- DELICATE (NCT05328180)
- Testing
- Sodium bicarbonate, Control arm
- Where
- Finland
- Volunteers
- 116 people
- Sponsor
- Kuopio University Hospital
Microbial Colonization, Infection, Bacterial
Microorganisms on Reusable Tourniquets
The purpose of this study was to compare microbial contamination on the surface of reusable stasis after indefinite use, 2 weeks and 4 weeks.
- Conditions
- Microbial Colonization, Infection, Bacterial, HAI, Nurse's Role
- Trial name
- NCT06566495
- Testing
- collection of microbiological material from reusable tourniquets
- Where
- Poland
- Volunteers
- 53 people
- Sponsor
- Medical University of Gdansk
Knee Osteoarthritis
Comparison of Three Tourniquet Application Methods in Primary Total Knee Arthroplasty Surgery
Different strategies of tourniquet application during elective primary total knee arthroplasty are thought to be associated with different outcomes.
- Trial name
- NCT01355900
- Testing
- Total knee arthroplasty performed under tourniquet
- Where
- Lithuania
- Volunteers
- 120 people
- Sponsor
- Vilnius University
Exanguination, Polytrauma
Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage in the Prehospital and Emergency Room Setting
This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital…
- Conditions
- Exanguination, Polytrauma, NCTH
- Trial name
- NCT07274150
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Knee Osteoarthritis
Tourniquet vs. no Tourniquet During High Tibial Osteotomy
The purpose of this study is to correlate functional outcomes and perioperative complications with tourniquet use during high tibial osteotomy.
- Trial name
- NCT04992533
- Testing
- Long-duration tourniquet, Short-duration tourniquet
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Qilu Hospital of Shandong University
Forearm Surgery, US-Guided Supraclavicular Block
Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
The etiology of tourniquet pain is complex, and the study team hypothesizes that blocking with Interscalene brachial plexus block (ISBPB) is more efficient in decreasing the incidence of tourniquet pain in comparison with other…
- Conditions
- Forearm Surgery, US-Guided Supraclavicular Block, Interscalene Analgesia, Tourniquet Pain
- Trial name
- NCT05602636
- Testing
- bupivacaine, midazolam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Carpal Tunnel Syndrome
Wide Awake Open Carpal Tunnel Release With or Without a Tourniquet
The goal of this clinical trial is to compare open carpal tunnel release using local anesthesia with or without a tourniquet. The main questions it aims to answer are: 1. Do the tourniquet cause more procedural pain? 2.
- Trial name
- NCT06172400
- Testing
- Mepivacaine, Combinations
- Volunteers
- 120 people
- Sponsor
- Region Skane
Osteoarthritis
Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty
To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B…
- Trial name
- NCT02102581
- Testing
- short time tourniquet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Osteoarthritis, Knee
Efficacy Testing of Different Tourniquet Pressure Used for Postoperative Pain Reduction in Total Knee Arthroplasty
Tourniquet use during total knee replacement (TKR) improves visibility, significantly decreases intra-operative blood loss and reduce operative time.
- Trial name
- NCT03931837
- Testing
- Tourniquet: Systolic blood pressure + 75 mmHg, Tourniquet: Systolic blood pressure + 100 mmHg, Tourniquet: Systolic blood pressure + 150 mmHg
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Anterior Cruciate Ligament Injury
Effect of Tourniquet Use on the Pivot Shift Test
This prospective study will evaluate whether tourniquet inflation affects the results of the pivot shift test in patients undergoing anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT07831941
- Testing
- Thigh Tourniquet Inflation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Umraniye Education and Research Hospital
Total Knee Arthroplasty
Clinical and Functional Outcomes of Tourniquet Use in Primary Total Knee Arthroplasty
Many surgeons choose to perform total knee arthroplasty (TKA) surgery with the aid of a tourniquet. A tourniquet is a device that fits around the leg and restricts blood flow to the limb.
- Trial name
- NCT05581563
- Testing
- total knee arthroplasty(TKA)
- Volunteers
- 100 people
- Sponsor
- Mongi Slim Hospital
Tourniquet Pain, Ischemia-reperfusion
The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress
The goal of this observational study is to learn about the relationship between postoperative pain and tourniquet-induced oxidative damage in adults undergoing orthopedic knee arthroscopy surgery.The goal of this observational…
- Conditions
- Tourniquet Pain, Ischemia-reperfusion, Postoperative Pain, Anesthesia
- Trial name
- NCT06942650
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Hemorrhage, Healthy Volunteers
Healthy Adults Aged 18-55, Three Ukrainian Windlass Tourniquets (SICH, DNIPRO GEN 2, PULS) Compared With CAT Gen 7, and Complete Limb Arterial Occlusion Confirmed by Doppler.
The goal of this clinical trial is to learn if three Ukrainian-made windlass tourniquets (SICH, DNIPRO GEN 2 and PULS) stop arterial blood flow in the arm or leg as well as the Combat Application Tourniquet (CAT Gen 7) does.
- Conditions
- Hemorrhage, Healthy Volunteers, Arterial Occlusion
- Trial name
- TORQUE (NCT07900360)
- Testing
- Windlass-type hemostatic tourniquet SICH, Windlass-type hemostatic tourniquet Dnipro, Windlass-type hemostatic tourniquet PULS, Windlass-type hemostatic tourniquet CAT Gen 7 (reference)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Foundation for Expert Deployment for Governance and Economic Growth (EDGE)
Carpal Tunnel Syndrome
WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release
Carpal tunnel syndrome (CTS) is a common medical condition that remains one of the most frequently reported forms of median nerve compression. Surgical procedure is a treatment option for CTS.
- Trial name
- WALAB (NCT06040840)
- Testing
- BAX, Tourniquet, Lidocaine
- Where
- France
- Volunteers
- 130 people
- Sponsor
- CMC Ambroise Paré