Clinical trials: Tracheal Stenosis
Tracheal Stenosis, Laryngeal Stenosis
Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells
The trial evaluates the safety and efficacy of the olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis
- Trial name
- NCT05535803
- Testing
- Olfactory mucosa-derived mesenchymal stem cells, Patients treated according to current clinical protocols
- Where
- Belarus
- Volunteers
- 20 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Respiratory Disease, Tracheal Stenosis
Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam
Rigid bronchoscopy usually requires deep general anesthesia, but the duration of the procedure is relatively short. Remimazolam, a recently developed anesthetics, showed faster recovery from anesthesia and stable hemodynamics…
- Conditions
- Respiratory Disease, Tracheal Stenosis, Endobronchial Mass
- Trial name
- NCT05835713
- Testing
- Remimazolam besylate, Propofol
- Sponsor
- Samsung Medical Center
Tracheal Stenosis
Stent Versus Balloon Dilatation in Patients With Tracheal Benign Stenosis
This is a retrospective, observational cohort study carried out in two operative Units of the University Hospital of Modena (Italy): the Diagnostic and Interventional Bronchoscopy Unit (Unit A) and the Otolaryngology Unit (Unit…
- Trial name
- STROBE (NCT04674995)
- Testing
- Stent placement
- Volunteers
- 66 people
- Sponsor
- University of Modena and Reggio Emilia
Idiopathic Subglottic Stenosis (iSGS)
Treatment Alternatives in iSGS (NoAAC PR-02 Study)
The study is aimed at answering the questions; (1) How well do the most commonly used treatments in iSGS work? and (2) What quality-of-life trade-offs are associated with each approach? With the results of this trial, the…
- Trial name
- NoAAC PR-02 (NCT02481817)
- Testing
- Endoscopic dilation of subglottic stenosis, Endoscopic resection of the stenosis, Tracheal Resection
- Where
- 42 sites in United States, Australia and 2 more
- Volunteers
- 1,239 people
- Sponsor
- Vanderbilt University Medical Center
Apnea+Hypopnea, Tracheal Dilatation
Tracheal Dilatation in Pediatric Patients With Acquired Tracheal Stenosis, and the Effects of Apneic Oxygenation
The study presents an alternative method of tracheal dilatation in pediatric patients with acquired tracheal stenosis. Dilatation is performed by the use of balloon catheter connected with manometer, that is bronchoscopic guided…
- Conditions
- Apnea+Hypopnea, Tracheal Dilatation, Igel, Tracheal Stenosis
- Trial name
- NCT05028023
- Testing
- Apneic oxygenation - supplemental high flow oxygen administration by an apneic way
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- Aristotle University Of Thessaloniki
Tracheal Stenosis
Challenges and Management of Post-intubation Tracheal Stenosis
Management of a "difficult airway" remains one of the most relevant and challenging tasks for anesthesiologists and pulmonary physicians.
- Trial name
- NCT06061380
- Testing
- no intervation taken
- Where
- Ethiopia
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Wollo University
Laryngeal Stenosis, Subglottic Stenosis
Study of Mitomycin-C Application in Laryngotracheal Stenosis
This is a randomized, prospective, double-blind, placebo-controlled clinical trial of the use of mitomycin-C topical application as an adjunctive treatment in the endoscopic surgical treatment of patients with laryngotracheal…
- Conditions
- Laryngeal Stenosis, Subglottic Stenosis, Tracheal Stenosis
- Trial name
- NCT01523275
- Testing
- Mitomycin -C, Saline application
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Trachea Diseases, Tracheal Stenosis
Feasibility of Tracheobronchial Reconstruction Using Bioengineered Aortic Matrices
We used a segment of cryopreserved aorta as a graft for reconstruction for long segment tracheobronchial lesion in human.
- Conditions
- Trachea Diseases, Tracheal Stenosis, Lung Cancer, Tuberculosis; Tracheitis
- Trial name
- NCT04850742
- Testing
- Cryopreserved aorta
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Tracheal Stenosis
Office-based Radial Expansion Balloon Dilation of the Esophagus and Trachea
Retrospective chart review of UCDMC patients who have undergone esophageal or tracheal balloon dilation to record data including age, gender, diagnosis pre-and post-procedure eating assessment tool, esophagoscopy findings…
- Trial name
- NCT00583960
- Sponsor
- University of California, Davis
Tracheal Stenosis, Subglottic Stenosis
Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis
Aim of the Work To compare the clinical outcomes between patients will undergo slide tracheoplasty and those will undergo tracheal resection anastomosis for acquired tracheal stenosis.
- Trial name
- NCT06917222
- Testing
- Slide tracheoplasty, Tracheal resection anastomosis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University Hospital
Tracheal Stenosis
A Clinical Trial on Effectiveness and Safety of Hydrogen Generator to Treat Dyspnea for the Patients With Tracheal Stenosis: A Randomized, Double-blind and Single-center Clinical Study
Investigators aim to study the effectiveness and safety of inhaling hydrogen-oxygen which produced by a hydrogen generator with nebulizer to decreases inspiratory effort for the patients with tracheal stenosis.
- Trial name
- NCT02961387
- Testing
- Hydrogen generator treatment, Oxygen-making machine treatment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Tracheal Stenosis
Role of Bronchoscopy in Assessment of Patients With Post-intubation Tracheal Stenosis
1. To estimate the importance of bronchoscopic treatment of tracheal stenosis and its effectiveness and safety. 2. To diagnose and evaluate tracheal stenosis characteristics as location, vertical extension and severity of…
- Trial name
- NCT04625400
- Testing
- bronchoscope
- Volunteers
- 87 people
- Sponsor
- Assiut University
Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus
Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair
Azygos vein preservation revisited: impact on early outcomes after repair of Esophageal atresia/ Tracheo-Esophageal Fistula in newborns. A randomized controlled study.
- Conditions
- Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus, Leak, Anastomotic, Stricture Esophagus
- Trial name
- EArAzygousvp (NCT05957562)
- Testing
- EA/TOF primary repair with Azygos vein preservation, EA/TOF primary repair with Azygos vein sacrifice (disconnection)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD
Tracheal Stenosis, COVID-19
Relationship Between Post-Intubation Tracheal Stenosis and Covid-19
Tracheal stenosis (TS) is a serious complication that occurs in approximately 6-22% of patients due to prolonged endotracheal intubation.
- Conditions
- Tracheal Stenosis, COVID-19, Post-Intubation Subglottic Stenosis, Intensive Care Unit
- Trial name
- NCT05682651
- Testing
- tracheal stenosis follow-up file
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ankara City Hospital Bilkent
Idiopathic Subglottic Stenosis
Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis
This study will examine the ability of steroid injections into the site of stenosis following surgical dilation to delay the need for repeated surgical dilations.
- Trial name
- ASTRO (NCT07228104)
- Testing
- Triamcinolone 0.1%
- Where
- 10 sites in United States
- Volunteers
- 226 people
- Sponsor
- Johns Hopkins University
Anomalies of Pulmonary Artery, Congenital
Relationship Between Tracheal and Left Pulmonary Artery Stenosis Index and Prognosis of PA Sling With Tracheal Stenosis
Pulmonary artery sling is a rare congenital pulmonary vascular malformation, often associated with tracheal or bronchial stenosis.
- Trial name
- NCT04383184
- Testing
- tracheoplasty
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Fudan University
Tracheal Stenosis, Laryngeal Stenosis
Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells
The trial evaluates the safety and efficacy of the olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis
- Conditions
- Tracheal Stenosis, Laryngeal Stenosis, Mesenchymal Stem Cells
- Trial name
- NCT03130374
- Testing
- Olfactory mucosa-derived mesenchymal stem cells
- Where
- 2 sites in Belarus
- Volunteers
- 12 people
- Sponsor
- The Republican Research and Practical Center for Epidemiology and Microbiology
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Tracheal Stenosis, Intensive Care Unit
Long-term Outcomes of Post-intubation Tracheal Stenosis; 7-year Follow-up
This retrospective, observational, cohort study evaluates the treatment management, long-term outcomes and survival analyses in patients hospitalized in the Intensive Care Unit with a diagnosis of Post-Intubation Tracheal…
- Trial name
- NCT06121024
- Testing
- Interventional Bronchoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital