Clinical trials: Transcranial Alternating Current Stimulations
Alzheimer Disease, Working Memory
Induction and Stabilization of Gamma Oscillations With 40 Hz External Brain Stimulation
The goal of the present studies is to develop and validate novel stimulation protocols for the entrainment of gamma oscillations, which are associated with many cognitive functions and critically involved in cognitive impairment…
- Conditions
- Alzheimer Disease, Working Memory, EEG Brain Oscillations
- Trial name
- NCT06680154
- Testing
- Transcranial alternating current stimulation, Theta burst stimulation
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Substance Dependence, Executive Function Disorder
Brain Mechanism and Intervention of Executive-control Dysfunction Among Substance Dependents
The investigators assume that tACS could improve amphetamine and alcohol dependent patients' executive-control function by adjusting the synchronization patterns and enhancing the functional connectivity of the prefrontal-ventral…
- Conditions
- Substance Dependence, Executive Function Disorder, Transcranial Alternating Current Stimulation
- Trial name
- NCT05312359
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Healthy
Modulating Speech Perception With Current Stimulation
This study aims to further develop tACS as a tool to improve speech perception, by manipulation of brain-speech synchronisation ("entrainment"), thereby transforming a promising approach into a technique that can benefit to…
- Trial name
- SPEECHSTIM (NCT05446350)
- Testing
- transcranial alternating current stimulation (tACS), electroencephalography (EEG), brain imaging (fMRI)
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Alcohol Use Disorder (AUD)
High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot Study
This one-arm pilot study aims to evaluate the preliminary clinical, behavioral, and neurophysiological effects of high-intensity transcranial alternating current stimulation (HI-tACS) in individuals with alcohol use disorder…
- Trial name
- HITACS-AUD (NCT07227545)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Mild Cognitive Impairment
Improvement of Memory in Mild Cognitive Impairment
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory…
- Trial name
- NCT05708001
- Testing
- transcranial alternating current stimulation (tACS), high-density electroencephalography (hdEEG), Montreal Cognitive Assessment (MoCA)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Transcranial Alternating Current Stimulation, Aging
Effects of Gamma-tACS on Memory and Sleep
The purpose of this clinical trial is to investigate the feasibility and efficacy of non-invasive transcranial alternating current stimulation (tACS) at gamma frequency in enhancing memory recall and modulating sleep network…
- Conditions
- Transcranial Alternating Current Stimulation, Aging, Cognitive Decline, Memory
- Trial name
- NCT05907707
- Testing
- Gamma transcranial alternating current stimulation, Control transcranial alternating current stimulation, EEG headband
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Use Disorder
A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol
The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during motivational interviewing (MI) sessions with participants who drink at…
- Trial name
- tACS-MI (NCT04770025)
- Testing
- High-density transcranial alternating current stimulation, Motivational interviewing
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Understand the Effects of tACS on the Brain
Investigating Transcranial Alternating Current Stimulation (tACS) Preconditioning Effects on Resting and Active Motor Threshold
Previous studies have looked at the potential of using transcranial direct current stimulation (tDCS) to prime the brain in order to lower the resting motor threshold.
- Trial name
- NCT05503823
- Testing
- tACS or tRNS and TMS
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Dyslexia
Role of Auditory Cortical Oscillations in Speech Processing and Dyslexia
This study aims at investigating the role of low-gamma activity in phonemic encoding and its implication in dyslexia. Indeed, a phonological deficit, i.e.
- Trial name
- NCT04277351
- Testing
- Transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Parkinson Disease
tACS Modulates Speech and Cognitive Impairments in People With PD by Targeting the Medial Frontal Cortex
This clinical trial aims to study whether transcranial alternating current stimulation (tACS) applied to the medial frontal cortex (MFC) can improve speech and cognitive function in people with Parkinson's disease (PD), and to…
- Trial name
- NCT07240272
- Testing
- 6Hz-tACS
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ke Dong, MD