Clinical trials: Transcranial Direct Current Stimulation
Healthy
Non-invasive Cerebellar Stimulation on Motor Learning
A crossover trial with healthy volunteers will be conducted. Six sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT02559518
- Testing
- tDCS, rTMS, pp-TMS assessment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Impulsivity, Decision Making
Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training and Decision-making
This study aims to (i) assess the effects of combined tDCS and cognitive training on decision-making on a trained task (Iowa Gambling Task; IGT); and (ii) test generalization to a closely related cognitive domain, namely motor…
- Trial name
- tDCS-CTDM (NCT03886025)
- Testing
- Anodal transcranial Direct Current Stimulation (tDCS), Cognitive training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Najat Khalifa
Nicotine Withdrawal, Tobacco Abstinence
Effects of Transcranial Direct Current Stimulation on Tobacco Withdrawal Symptoms
We hypothesize that transcranial direct current stimulation will reduce tobacco withdrawal symptoms of tobacco dependent smokers abstinent from smoking for more than 10 hours.
- Trial name
- tDCSsmokers (NCT01567982)
- Testing
- tDCS, prefrontal cortex and parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Pain Modulation
Evaluation of the Hypoalgesic Effects of Transcranial Direct Current (tDCS) in Healthy Subjects
The main objective of this research is to evaluate and quantify hypoalgesic effects caused by imagination and observation with or without the presence of transcranial direct current (tDCS) in healthy participants.
- Trial name
- NCT04127253
- Testing
- Sooma transcranial direct current stimulation device plus Brain training tools, Brain training tools in isolation
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Endometriosis, Pelvic Pain
tDCS Versus tsDCS for Endometriosis-related Chronic Pelvic Pain Treatment
The purpose of the study is to compare the analgesic effect of 2 mA anodal direct current stimulation on the right primary motor cortex (M1) (tDCS) with a similar stimulation on the spine (D10) (tsDCS) in healthy volunteers (HV)…
- Conditions
- Endometriosis, Pelvic Pain, Transcranial Direct Current Stimulation, Spinal Cord Stimulation
- Trial name
- DCSErCPP (NCT02958423)
- Testing
- Transcranial DCS Healthy Volunteers, Transspinal DCS Healthy Volunteers, Transcranial DCS CPP patients
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jean Schoenen
Stroke
Efficacy of TOCT and (tDCS) for Gait Improvement in Patients With Chronic Stroke
Stroke is one of the major causes of disability in the Western world. Initially gait is the most affected function, 80% of patients lose this ability.
- Trial name
- NCT01883843
- Testing
- real tDCS + TOCT
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Traumatic Brain Injury
Relationship Between Attention and Emotional Regulation Post-Traumatic Brain Injury (TBI)
The purpose of this pilot study is to investigate the relationship between attention and emotional function post-Traumatic Brain Injury (TBI) in an effort to better understand the cognitive mechanisms of emotional processing in…
- Trial name
- NCT01681589
- Testing
- Transcranial Direct Current Stimulator (TDCS), Control Group, Healthy Control Group
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer, Cognitive Dysfunction
Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation
This study will test the preliminary efficacy of transcranial direct current stimulation (tDCS) to improve fatigue and cognition in women with a history of breast cancer and persistent fatigue.
- Conditions
- Breast Cancer, Cognitive Dysfunction, Fatigue
- Trial name
- NCT03143894
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy, Brain Stimulation
Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults
The objective of this randomized, double-blind, sham-controlled, crossover study is to evaluate the effects of transcranial electrical stimulation (tES) on complex cognitive task performance in healthy adult volunteers.
- Conditions
- Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition
- Trial name
- BRAIN-STIM (NCT06995560)
- Testing
- Active Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
tDCS, Cues Type
tDCS and the Gaze Cueing Effect
This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.
- Conditions
- tDCS, Cues Type, SOA, Congruency
- Trial name
- NCT07592559
- Testing
- Gaze cues, Arrow cues, SOA 200 ms
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Low Back Pain
Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic…
- Trial name
- NCT05156242
- Testing
- Active-tDCS priming MCE, NMES priming MCE, Conventional physical therapy
- Where
- Thailand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Stroke
Tactile Learning in Stroke Patients
This study will determine if stimulation of the stroke-injured side of the brain combined with stimulation to the paralyzed hand can temporarily improve the sense of touch in stroke patients.
- Trial name
- NCT00283881
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cancer-related Fatigue, Neuromodulation
tDCS for Cancer-Related Fatigue and Weakness
This pilot study investigates the effectiveness of non-invasive brain stimulation (tDCS) in alleviating cancer-related fatigue (CRF) and muscle weakness.
- Trial name
- NCT07159100
- Testing
- Active tDCS + elbow flexion exercise
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Visceral Pain, Pancreatitis
Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain
This study investigates comparing the effects of transcranial Pulsed Current Stimulation and transcranial Direct Current Stimulation (tDCS) (Soterix ©) and their combination on neurophysiological outcomes on healthy subjects as…
- Conditions
- Visceral Pain, Pancreatitis, Pelvic Pain
- Trial name
- NCT02497196
- Testing
- Active tPCS, Active tDCS
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Aging
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults
The tDCS \& Dual Tasking study will compare the effects of transcranial Direct Current Stimulation (tDCS) targeting three different cortical regions (as well as sham stimulation) on dual task standing and walking in older adults…
- Trial name
- NCT03191812
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Inflammatory Bowel Diseases
Transcranial Direct Current Stimulation and the Interaction Between Chronic Pain and the Intestinal Epithelial Barrier in Patients With Chronic Inflammatory Bowel Diseases (IBD)
In the study the investigators aim to test whether transcranial direct current stimulation (tDCS) induced pain reduction is in association with functional changes in the brain measured with magnetic resonance imaging (MRI) and…
- Trial name
- NCT03825900
- Where
- Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Major Depressive Disorder, Schizophrenia
Disorder-tailored Transcranial Direct Current Stimulation (tDCS) of the Prefrontal Cortex
Major depressive disorder (MDD) is a common, recurrent, and frequent chronic disorder. Among others, deficient cognitive control over emotional distraction is a central characteristic of MDD (Ochsner \& Gross 2005; Disner et al.
- Trial name
- MRSDC1 (NCT02715128)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Cognitive Flexibility
Modulation of Cognitive Flexibility by Tyrosine Depletion and Transcranial Direct Current Stimulation
The dorsolateral prefrontal cortex (dlPFC) and dopamine (DA) have been implicated in the control of cognitive flexibility. However, while a great deal of what it is know regarding a causative relationship between cognitive…
- Trial name
- NCT03462303
- Testing
- Anodal tDCS and tyrosine depleted drink, Anodal tDCS and balanced drink
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Amblyopia
Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia
As a neurodevelopmental visual disorder, amblyopia, especially monocular form-deprivation amblyopia, can lead to severe visual developmental impairments.
- Trial name
- NCT06760910
- Testing
- tDCS Stimulation, Anodal tDCS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital