Clinical trials: Transcranial Electrical Stimulation
Stroke, Cerebrovascular Accident
Spinal Plasticity to Enhance Motor Retraining After Stroke
The objective of this project is to study the effects of an emerging noninvasive neuromodulation strategy in human stroke survivors with movement-related disability.
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT03645122
- Testing
- Paired corticospinal-motoneuronal stimulation (PCMS)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Performance Enhancing Product Use, Sleep
Optimizing Volunteer Comfort for Transcranial Electrical Stimulation (TES): An Assessment
Transcranial electrical stimulation (TES) utilizing weak electrical fields (<5 milliamps of current - as proposed in the present pilot study) is an extremely safe therapeutic technique in use for over 40 years.
- Trial name
- TES (NCT04474015)
- Testing
- transcranial electric stimulation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Transcutaneous Electrical Nerve Stimulation
Effects of Transcutaneous Electrical Nerve Stimulation on Cortical Excitability in the Primary Motor Cortex in Healthy Adults
Recently, non-invasive brain stimulation has become a powerful tool in both basic research and clinical application. Among several non-invasive brain stimulation techniques, transcranial magnetic stimulation (TMS) and…
- Trial name
- NCT02077595
- Testing
- transcutaneous electrical nerve stimulation, TENS
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Fall, Gait, Unsteady
Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait)
Walking is a complex and continuous task that entails repetitive motions of the body. Relatively high gait variability sensitively predicts falls and cognitive decline in older adults.
- Conditions
- Fall, Gait, Unsteady, Mobility Limitation
- Trial name
- NCT06008431
- Testing
- Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Language Development, Learning
Brain Stimulation Paired With Structured Language Learning in Adults
This study investigates whether transcranial electrical stimulation (tES) delivered during structured language-learning sessions affects the rate and quality of second-language acquisition in adults.
- Trial name
- NCT07762118
- Testing
- Active transcranial electrical stimulation (tES)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- General Neuro Inc.
Transcranial Direct Current Stimulation (tDCS), Ageing
Investigating the Effectiveness of a 2-week Novel Non-invasive Brain Stimulation Technique on Cognitive Outcomes in Healthy Adults
The goal of this randomised controlled trial is to investigate the effects of a 2-week high-frequency transcranial pulsed current stimulation (tPCS) on cognitive outcomes in older and healthy adults.
- Conditions
- Transcranial Direct Current Stimulation (tDCS), Ageing, Executive Functioning, Transcranial Electric Stimulation
- Trial name
- NCT06991764
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Changes in EEG During and After Magnetic Stimulation
The Effect of Repetitive Transcranial Magnetic Stimulation on Brain Activity in Healthy Human Volunteers
The proposed study is designed to determine whether small changes in the positioning of a transcranial magnetic stimulation coil over the frontal parts of the brain cause different patterns of brain activation measured by…
- Trial name
- ERP (NCT01369264)
- Testing
- true left high frequency
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Stroke
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only one region.
- Trial name
- NCT05638464
- Testing
- multisite HD-tDCS EMG-driven robot hand
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mild Traumatic Brain Injury (mTBI), Post-traumatic Stress Disorder
Transcranial Electrical Stimulation for mTBI
mTBI is a leading cause of sustained physical, cognitive, emotional, and behavioral deficits in OEF/OIF/OND Veterans and the general public.
- Trial name
- TESmTBI (NCT03244475)
- Testing
- TES
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Transcranial Direct Current Stimulation
Mechanism and Dosimetry Exploration in TES Magnetic Resonance Current Mapping Methods
In this study the investigators will explore dosimetry in transcranial electrical stimulation using a novel magnetic resonance imaging technique that can determine how electrical stimulation distributes within the brain.
- Trial name
- TES (NCT03772210)
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Memory Disorders in Old Age
Improving Working Memory in Older Adults
The research program will evaluate the theoretical claim that age-related memory and cognitive decline in humans result from the inefficient orchestration of rhythmic activity within large-scale cortical networks.
- Trial name
- NCT04362696
- Testing
- High definition transcranial electrical current stimulation
- Where
- United States
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Healthy, Schizophrenia
Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation
Experience dependent plasticity is a fundamental property of the brain. It allows neural systems to adapt in response to environmental input and subserves the vital functions of learning and memory.
- Trial name
- NCT03114488
- Testing
- tDCS
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Healthy
Influence of Transcranial Direct Stimulation Current on Motor Learning of Young Adults
Motor learning occurs with structural and functional modifications in neural networks that meet a certain demand. The improvement of performance in diverse activities is a measure of learning, as well as the generalization and…
- Trial name
- NCT03157869
- Testing
- Transcranial Direct Current Stimulation, Simulated
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy Subjects (HS)
Aftereffects of PES Preconditioned with RTMS on the Human Pharyngeal Motor Cortex
The goal of this interventional study is to optimize the excitatory brain effects of combined neuromodulatory therapies on swallowing areas of the brain.
- Trial name
- NCT06884488
- Testing
- repetitive transcranial magnetic stimulation (Magstim Super Rapid stimulator, The Magstim Company Ltd, Whitland, UK), pharyngeal electrical stimulation (Digitimer model DS7; Welwyn-Garden City, Herts, UK)
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Spinal Cord Injuries
Non-invasive Cervical Electrical Stimulation for SCI
Most spinal cord injuries (SCI) are anatomically incomplete - some nerve circuits remain intact, even if the individual cannot feel or control them. Activating spared nerve circuits may improve functional recovery.
- Trial name
- NCT03414424
- Testing
- CES at rest, CES plus active hand or wrist movements
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Parkinson' Disease
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on…
- Trial name
- ExtDCSPARK (NCT07524400)
- Testing
- real tDCS and exercise, Exercise
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Reward-guided Behaviour
Oscillations in Reward-guided Behavior
While people are reading, talking or playing computer games, their brain cells elicit electrical signals so they could perform these actions.
- Trial name
- NCT04761471
- Testing
- TI transcranial electrical stimulation
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Aging
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults
The tDCS \& Dual Tasking study will compare the effects of transcranial Direct Current Stimulation (tDCS) targeting three different cortical regions (as well as sham stimulation) on dual task standing and walking in older adults…
- Trial name
- NCT03191812
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife