Clinical trials: Transcranial Electrical Stimulation, open to volunteers
Multiple Sclerosis
Improving Hand Movement and Coordination in People With Multiple Sclerosis Using Transcranial Magnetic Stimulation (TMS) and Muscle Electrostimulation (FES) To Support Manual Dexterity and Daily Function
The goal of this interventional study is to test whether combining transcranial magnetic stimulation (TMS) with functional electrical stimulation (FES) can improve hand and upper limb function in adults with Multiple Sclerosis…
- Trial name
- MANTRAStim (NCT07098273)
- Testing
- TMS and FES- based rehabilitation, FES-based rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Disorder of Consciousness
Alpha tACS for Disorders of Consciousness : a Single Case Experimental Design
BRIEF SUMMARY * (Include a statement of the study hypothesis) Avoid all personal pronouns (Limit: 5000 characters) Disorders of consciousness (DoC) following a severe traumatic brain injury represent a major medical challenge…
- Trial name
- SPARC (NCT07213869)
- Testing
- Transcranial alternating current stimulation (tACS)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Parkinson Disease (PD)
MRI-Guided Temporal Interference Stimulation for Parkinson's Disease
This study aims to evaluate the efficacy and safety of tTIS treatment in patients with Parkinson's disease (PD). The study will enroll eligible PD patients and randomly assign them to two groups: Group A will first receive…
- Trial name
- NCT07827456
- Testing
- Temporal Interference Stimulation (130 Hz)
- Volunteers
- 26 people
- Sponsor
- Tongji Hospital
Dyslexia, Reading Disability
Brain Stimulation Paired With Structured Reading Instruction in Children With Dyslexia
This study investigates whether transcranial electrical stimulation (tES) delivered during structured reading instruction affects reading proficiency in children with developmental dyslexia and related reading disabilities.
- Trial name
- NCT07762365
- Testing
- Active transcranial electrical stimulation (tES)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- General Neuro Inc.
Amyotrophic Lateral Sclerosis (ALS)
HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial
Amyotrophic Lateral Sclerosis (ALS) is a nervous system disease that causes muscle weakness and rapidly progresses to the loss of mobility and functionality.
- Trial name
- tDCS-ALS (NCT06719947)
- Testing
- Active HD-tDCS, Simulated HD-tDCS
- Where
- 4 sites in Brazil, Chile
- Volunteers
- 80 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Presbyopia, Esotropia
Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation Dysfunction
This is a single-center, randomized controlled trial to compare the effectiveness of transcranial electrical stimulation combined with visual training with visual training alone for the treatment of accommodation disorder…
- Trial name
- NCT06714890
- Testing
- Transcranial Electrical Stimulation, Visual Training
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Stress, Sleep
Effects of Transcranial Electrical Stimulation in Chronic Stress
This clinical trial aims to determine if Transcranial electrical stimulation by direct current (tDCS) and transauricular Vagus Nerve Stimulation (tVNS) treatments are effective in reducing stress symptoms, distress and improving…
- Trial name
- NEUROSTIM (NCT06813209)
- Testing
- tDCS, tVNS
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Performance Enhancing Product Use, Sleep
Optimizing Volunteer Comfort for Transcranial Electrical Stimulation (TES): An Assessment
Transcranial electrical stimulation (TES) utilizing weak electrical fields (<5 milliamps of current - as proposed in the present pilot study) is an extremely safe therapeutic technique in use for over 40 years.
- Trial name
- TES (NCT04474015)
- Testing
- transcranial electric stimulation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Spinal Cord Injury
Influence of Transcranial Electrical Stimulation on Arm and Hand Function After Cervical Spinal Cord Injury
The goal of this pilot study is to find out how four different types of transcranial electrical stimulation (tES) affect brain activity, the process of acquiring new skills (also called motor learning), and hand function after…
- Trial name
- NCT07909317
- Testing
- transcranial direct current stimulation (tDCS) + FTP, transcranial pulsed current stimulation (tPCS) + FTP, transcranial random noise stimulation (tRNS) + FTP
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shepherd Center, Atlanta GA
Traumatic Brain Injury (TBI) Patients
Early Neuromodulation in Traumatic Brain Injury
The two goals of the proposed study are: (1) To determine how brain activity changes with cognitive recovery over time from acute to chronic phases of traumatic brain injury (TBI).
- Trial name
- NCT06871124
- Testing
- transcranial electrical stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Primary Progressive Aphasia(PPA)
Long Term Effect of Brain Stimulation in PPA
The goal of this clinical trial is to investigate the effect of non-invasive brain stimulation techniques in the progression of primary progressive aphasia for 6 months.
- Trial name
- RECONNECT-PLUS (NCT07158216)
- Testing
- TMS, tDCS
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital San Carlos, Madrid
Disorder of Consciousness, Stroke
Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients.
- Trial name
- NCT05706831
- Testing
- Combinatory effect of music stimulation and neurostimulation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Transcranial Electric Stimulation
Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking
This study is to find out whether and how a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity in healthy adults.
- Trial name
- MINT (NCT07752745)
- Testing
- TES-TI with hdEEG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hemiparesis, Ischemic Stroke
Dynamic Stabilometry Combined With Transcranial Direct Current Stimulation for Balance and Motor Recovery After Ischemic Stroke
The goal of this clinical trial is to learn if balance training on a moving (dynamic) platform with visual and sound feedback, combined with weak electrical brain stimulation, helps people recover balance and movement after an…
- Conditions
- Hemiparesis, Ischemic Stroke, Stroke Rehabilitation, Postural Balance
- Trial name
- STAB-tDCS (NCT07912151)
- Testing
- Dynamic Stabilometry With Biofeedback, Static Stabilometry, Anodal tDCS
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Samara State Medical University
Substance Use Disorders
Enhancing Addiction Treatment Through Psychoeducation
Addiction is a brain disorder characterized by a broad range of both apparent and subtle cognitive impairments in attention, memory, executive functions, and decision-making.
- Trial name
- NCT07178158
- Testing
- Installing the Metacognium software app, Continue treatment as usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Hemorrhagic Stroke, Ischemic Stroke
Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Motor Performance in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and…
- Conditions
- Hemorrhagic Stroke, Ischemic Stroke, Subacute Stroke, Chronic Stroke Patient
- Trial name
- NCT07236216
- Testing
- High-definition transcranial direct current stimulation (Active), High-definition transcranial alternating stimulation (Active), Cognitive-motor dual task gait training
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Menopausal Depression, Menopause Hot Flashes
Transcranial Electrical Stimulation for Noninvasive Study of Menopausal/Perimenopausal Symptoms
Participants are being invited to a research study. This research aims to assess the tolerability of transcranial electrical stimulation of the brain, and explore the response of TES on menopausal/perimenopausal symptoms…
- Conditions
- Menopausal Depression, Menopause Hot Flashes, Menopause, Menopause Related Conditions
- Trial name
- NCT07375732
- Testing
- Transcranial Electrical Stimulation
- Volunteers
- 50 people
- Sponsor
- Carnegie Mellon University
Generalized Anxiety Disorder (GAD)
Therapeutic Effect of Neuromodulation on Anxiety Disorders by High-Definition Transcranial Electrical Stimulation
High-definition transcranial electrical stimulation (HD-tES) is a non-invasive brain neuromodulation technique that applies a small electrical current to the scalp to alter neural excitability and stimulate localized brain…
- Trial name
- NCT06775145
- Testing
- HD-R_cDC+cTBS & HD-L_aDC+iTBS
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Depression Disorder, Chronic Pain
Transcranial Electrical Stimulation for Comorbid Depression and Chronic Pain
The goal of this clinical trial is to learn if active transcranial alternating current stimulation (tACS) and transcranial direct current stimulation (tDCS) can improve pain symptoms in patients with major depressive disorder…
- Trial name
- NCT07334561
- Testing
- tDCS, alpha-tACS
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Shanghai Mental Health Center
Dementia
Investigating Different Frequencies of Transcranial Electrical Stimulations in Dementia Population
Dementia is a prevalent condition with no known cure. It affects not only the person with dementia but also the family. This study will investigate the effects of applying different transcranial electrical stimulation (tES)…
- Trial name
- NCT06547021
- Testing
- Transcranial Direct Current Stimulation (tDCS), Gamma Transcranial Alternating Current Stimulation (tACS), Theta Transcranial Alternating Current Stimulation (tACS)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba