Clinical trials: Transcranial Electrical Stimulation (tES), open to volunteers
Closed-loop Brain Stimulation
Closed-loop tES-non-invasive Stimulation
The goal of this study is to establish if non-invasive closed-loop neuromodulation is an effective approach to enhance cognitive function in healthy 18-40 years old volunteers.
- Trial name
- CLIBM (NCT07671079)
- Testing
- Transcranial low intensity focused ultrasound (FUS), transcranial electrical stimulation, Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Retinitis Pigmentosa (RP), Rod Cone Dystrophy
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
This pilot clinical trial evaluates whether non-invasive brain stimulation improves the orientation and mobility (O\&M) skills of individuals with constricted visual fields in both eyes. The study is composed of three visits.
- Conditions
- Retinitis Pigmentosa (RP), Rod Cone Dystrophy, Visually Impaired Persons, Peripheral Visual Field Defect of Both Eyes
- Trial name
- NCT07341763
- Testing
- Active hf-tRNS.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Waterloo
Language Development, Learning
Brain Stimulation Paired With Structured Language Learning in Adults
This study investigates whether transcranial electrical stimulation (tES) delivered during structured language-learning sessions affects the rate and quality of second-language acquisition in adults.
- Trial name
- NCT07762118
- Testing
- Active transcranial electrical stimulation (tES)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- General Neuro Inc.
Depression - Major Depressive Disorder
Dual Neuromodulation for Depression: Boosting TMS With tES
Major depressive disorder (MDD) is a common and disabling condition. Transcranial magnetic stimulation (TMS) is an established non-invasive neuromodulation treatment for depression, but clinical response varies considerably…
- Trial name
- DUAL MOD (NCT07879924)
- Testing
- Transcranial Magnetic Stimulation, Transcranial Alternating Current Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Mersey Care NHS Trust
PARKINSON DISEASE (Disorder)
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease.
- Trial name
- NCT07182058
- Testing
- Transcranial Electrical Stimulation Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- U: The Mind Company
Schizophrenia
Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep…
- Trial name
- ONSETS (NCT07680114)
- Testing
- TES-TI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sleep Deprivation, Mental Competency
Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep
The purpose of this study is to determine if the enhancement of electroencephalographic (EEG) slow-wave activity using transcranial electrical stimulation (TES) at Slow Oscillation (SO) frequency, during a restricted period of…
- Trial name
- NCT02945501
- Testing
- NeuroConn DC Stimulator PLUS
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Disorder of Consciousness
Alpha tACS for Disorders of Consciousness : a Single Case Experimental Design
BRIEF SUMMARY * (Include a statement of the study hypothesis) Avoid all personal pronouns (Limit: 5000 characters) Disorders of consciousness (DoC) following a severe traumatic brain injury represent a major medical challenge…
- Trial name
- SPARC (NCT07213869)
- Testing
- Transcranial alternating current stimulation (tACS)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Dyslexia, Reading Disability
Brain Stimulation Paired With Structured Reading Instruction in Children With Dyslexia
This study investigates whether transcranial electrical stimulation (tES) delivered during structured reading instruction affects reading proficiency in children with developmental dyslexia and related reading disabilities.
- Trial name
- NCT07762365
- Testing
- Active transcranial electrical stimulation (tES)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- General Neuro Inc.
Performance Enhancing Product Use, Sleep
Optimizing Volunteer Comfort for Transcranial Electrical Stimulation (TES): An Assessment
Transcranial electrical stimulation (TES) utilizing weak electrical fields (<5 milliamps of current - as proposed in the present pilot study) is an extremely safe therapeutic technique in use for over 40 years.
- Trial name
- TES (NCT04474015)
- Testing
- transcranial electric stimulation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Transcranial Electric Stimulation
Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking
This study is to find out whether and how a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity in healthy adults.
- Trial name
- MINT (NCT07752745)
- Testing
- TES-TI with hdEEG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Substance Use Disorders
Enhancing Addiction Treatment Through Psychoeducation
Addiction is a brain disorder characterized by a broad range of both apparent and subtle cognitive impairments in attention, memory, executive functions, and decision-making.
- Trial name
- NCT07178158
- Testing
- Installing the Metacognium software app, Continue treatment as usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Hemorrhagic Stroke, Ischemic Stroke
Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Motor Performance in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and…
- Conditions
- Hemorrhagic Stroke, Ischemic Stroke, Subacute Stroke, Chronic Stroke Patient
- Trial name
- NCT07236216
- Testing
- High-definition transcranial direct current stimulation (Active), High-definition transcranial alternating stimulation (Active), Cognitive-motor dual task gait training
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University