Clinical trials: Transdiagnostic
Dysautonomia, Anxiety
Implementation of Transdx Group for POTS
The proposed intervention is focused on developing and implementing a psychological approach incorporated into a group-based outpatient intervention for pediatric autonomic dysfunction.
- Conditions
- Dysautonomia, Anxiety, Depression
- Trial name
- NCT03185247
- Testing
- Transdiagnostic Group-Based Treatment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sexual Violence
Developing and Testing a Trauma-Informed Exercise Intervention for Women Veterans With Histories of Sexual Violence
Exposure to sexual violence disproportionally impacts women Veterans and can have profound negative impacts on daily functioning.
- Trial name
- NCT06746740
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Emotional Disorders, Anxiety
Unified Protocol Group Treatment in a University Outpatient Clinic
This clinical trial aims to evaluate the effectiveness and underlying processes of change of the Unified Protocol (UP) for treating emotional disorders in a university outpatient clinic.
- Conditions
- Emotional Disorders, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07129941
- Testing
- Unified Protocol
- Where
- Norway
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Anxiety Disorders
Transdiagnostic Treatment for Anxiety Disorders in Two Cities of México
This study evaluates the effectiveness of The Unified Transdiagnostic Protocol, a psychological treatment for the intervention of a broad range of anxiety disorders.
- Trial name
- NCT03916315
- Testing
- Transdiagnostic Treatment
- Where
- 2 sites in Mexico
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Depressive Disorder, Anxiety Disorders
Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression
Psychological therapies for depression have demonstrated efficacy, but outcomes are still unsatisfactory, especially in cases with high comorbidity.
- Trial name
- NCT01829100
- Testing
- Group Behavioral Activation Therapy (GBAT)
- Where
- United States
- Volunteers
- 895 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Cancer Survivors
Improving Sleep, Fatigue, Activity & Quality of Life in Cancer Survivors Via a Transdiagnostic Intervention
Poor sleep affects over half of U.S. cancer survivors, contributing to daytime fatigue, reduced physical activity, and diminished quality of life.
- Trial name
- SLEEP-CARE (NCT07023783)
- Testing
- Transdiagnostic Sleep Health Intervention (TSHI)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
The Focus is the Prevention and Promotion of Mental Well-being and is a Universal Delivery Intervention
Promotion of Mental Health in Adolescents: A School-Based Preventive Version of the Unified Protocol (UP-A Kind)
The goal of this clinical trial is to assess the efficacy of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders for Adolescents (UP-A; Ehrenreich-May et al., 2018) as a universal school-based preventive…
- Trial name
- UP-A Kind (NCT07021001)
- Testing
- UP-A, a cognitive-behavioral structured group intervention, was adapted as a universal preventive intervention to be delivered in school settings (UP-A Kind).
- Where
- Portugal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Major Depressive Disorder, Bipolar Disorder
Transdiagnostic Markers of Cognitive Symptoms in Disorders Affective.
The objective of this project is to determine the concordance between the subjective and objective evaluation of cognitive functions in affective patients in partial remission through scales and cognitive tests that would be…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, BDMF, GSH
- Trial name
- NCT05523076
- Where
- Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Alcohol Use, College Drinking
Building Undergraduate Coping & Knowledge for Stress-Resilience
Nearly 60% of college students use alcohol and 30% binge drink monthly. This is alarming given that heavy alcohol use is linked to serious detrimental outcomes.
- Conditions
- Alcohol Use, College Drinking, Anxiety
- Trial name
- BUCKS (NCT06885320)
- Testing
- IMPROVE, HET
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Emotion Regulation
Process Evaluation of the Effectiveness of Two Transdiagnostic Interventions on Emotion Regulation
Emotional regulation (ER) appears today as a fundamental skill for the adaptation of an individual to his environment. Indeed, functional and efficient ER is crucial for mental well-being, but also for physical health, for the…
- Trial name
- INTREC (NCT05113680)
- Testing
- compassion focused group, emotional competencies
- Where
- France
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University Grenoble Alps
Circadian Dysregulation
Maintaining Behavior Change: An Evaluation of a Habit-based Sleep Health Intervention
The study will test a sleep-health intervention that leverages the science on habit formation. It will evaluate if adding a text messaging intervention improves habit formation. The participants will be 18-30 years old.
- Trial name
- NCT05167695
- Testing
- Habit-based Sleep Health Intervention, Text messaging intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Depression, Anxiety
Mechanisms of Anxiety and Depression Study
Eligible participants will come in for three separate visits in which they will be interviewed, perform a variety of tasks, and undergo a non-invasive MRI scan.
- Trial name
- NCT03135756
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Palo Alto University
Antenatal Depression, Antenatal Anxiety
Effectiveness and Cost-effectiveness of Simultaneous Screening and Intervention for Antenatal Depression and Anxiety Symptoms From a Transdiagnostic Perspective: A Scale-up Feasibility Study
This scale-up study aimed to explore the effectiveness of simultaneous screening and intervention of antenatal depression and anxiety in preventing postpartum depression and anxiety and how scale-up might be successfully…
- Trial name
- NCT07349368
- Testing
- implementation group
- Where
- China
- Volunteers
- 3,314 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Depression, Insomnia
A Transdiagnostic Sleep and Circadian Treatment for Depression
This study will examine the use of a transdiagnostic Sleep and Circadian Treatment (TranS-C) in treating Major Depressive Disorder (MDD) in Chinese adults.
- Trial name
- NCT03775148
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)
- Where
- Hong Kong
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Emotional Disorder, Stress Related Disorder
Online Transdiagnostic Intervention for Emotional Disorders and Stress-related Disorders
The general objective of this study is to determine the indicators of suitability, clinical utility and satisfaction of the transdiagnostic online intervention for the treatment of emotional disorders and those derived from…
- Conditions
- Emotional Disorder, Stress Related Disorder, Anxiety Disorders, Depression
- Trial name
- NCT05081830
- Testing
- Transdiagnostic online intervention, TCC online intervention
- Where
- Mexico
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Insomnia, Anxiety
Treating Comorbid Insomnia in Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy
Transdiagnostic Internet-delivered Cognitive Behaviour Therapy (ICBT) is an efficacious treatment option for anxiety and depression; however, not all patients benefit equally and some leave treatment before program completion.
- Conditions
- Insomnia, Anxiety, Depression
- Trial name
- NCT04512768
- Testing
- Transdiagnostic Internet-delivered Cognitive Behaviour Therapy, Brief Internet-Delivered Cognitive Behaviour Therapy for Insomnia
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Regina
Psychological Distress, Trauma, Psychological
Feasibility Study of a Group Intervention for Youth Wellbeing
Psychological distress, anxiety and depression are common in adolescence, and even more so following traumatic events. On Friday 15 March 2019, two mosques in Ōtautahi, Christchurch were targeted in an act of terrorism, resulting…
- Conditions
- Psychological Distress, Trauma, Psychological, Emotional Problem
- Trial name
- NCT05030909
- Testing
- transdiagnostic group treatment
- Where
- New Zealand
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Otago
Behavior Problem
Effectiveness of the MY LIFE Treatment for Adolescents With Behavioral Problems
Objective This study examines the effects of the MY LIFE treatment, a group intervention aiming to increase hope, self-worth and social support seeking in adolescents with behavioral problems in mental health care.
- Trial name
- NCT05581914
- Testing
- MY LIFE treatment, Care as Usual
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Emotion Regulation, Stress
Optimization of a Mobile Transdiagnostic Emotion Regulation Intervention for University Students
This study will explore the functioning of a mobile transdiagnostic emotion regulation intervention designed for university students to optimize the uptake and the effectiveness of the intervention.
- Conditions
- Emotion Regulation, Stress, Depressive Symptoms, Anxiety
- Trial name
- NCT05576883
- Testing
- Transdiagnostic emotion regulation intervention
- Where
- Netherlands
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Erasmus University Rotterdam