Clinical trials: Transient Ischemic Attack (TIA)
Non-valvular Atrial Fibrillation
Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation
The purpose of this study are 1) to characterize the primary and secondary prevention patients, 2) to calculate incidence rates of stroke/SE or major bleeding in each cohort and 3) to investigate for Japanese secondary prevention…
- Trial name
- NCT05321810
- Testing
- Apixaban, Warfarin
- Where
- Japan
- Volunteers
- 193,565 people
- Sponsor
- Pfizer
Ischemic Stroke, Transient Ischemic Attack
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients.
- Trial name
- SAFEST - RCT (NCT06785727)
- Testing
- Statin (atorvastatin, fluvastatin, pravastatin, rosuvastatin or simvastatin)
- Volunteers
- 612 people
- Sponsor
- Prof. dr. Nathalie van der Velde
Cerebrovascular Event, Acute Ischemic Stroke
Prospective Italian Validation of SMS in Patients With Suspected Acute Stroke
The overall objective of the study is to prospectively validate the diagnostic accuracy of the Stroke Mimics Score (SMS). This score is calculated using information collected at the time of the patient's arrival in the Emergency…
- Conditions
- Cerebrovascular Event, Acute Ischemic Stroke, Intracerebral Hemorrhage, TIA (Transient Ischemic Attack)
- Trial name
- PIVA-SMS (NCT07601659)
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Intracerebral Infarcts, Ischemic Stroke
Discharge Educational Strategies for Reduction of Vascular Events
DESERVE is a discharge education study using health workers to enroll and randomly assign 800 subjects diagnosed with TIA, or mild stroke to either risk factor education or usual care.
- Conditions
- Intracerebral Infarcts, Ischemic Stroke, Hemorrhagic Strokes, TIA's
- Trial name
- DESERVE (NCT01836354)
- Testing
- DESERVE education
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- NYU Langone Health
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Stroke, Ischemic Attack, Transient
Home Blood Pressure Monitoring Trial
Design: Community based randomised trial with follow up after 12 months Participants: 360 patients admitted with stroke or TIA within the past 9 months will be recruited from the wards or outpatients and randomly allocated into…
- Trial name
- NCT00514800
- Testing
- Intervention - a validated home BP monitor and support from the specialist nurse, Control - usual care (BP monitoring by their practice)
- Where
- 3 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- St George's, University of London
Stroke, Transient Ischemic Attack
A Person-centred Care Transition Support for People With Stroke/TIA
The goal of this clinical trial is to test a person-centred care transition support in people with stroke/TIA. The main questions it aims to answer are: Does a multi-component care transition intervention have an effect on…
- Trial name
- Missing Link (NCT05646589)
- Testing
- Person-centred care transition support, Regular care transition
- Where
- 3 sites in Sweden
- Volunteers
- 213 people
- Sponsor
- Karolinska Institutet
Coronary Disease, Cerebral Infarction
The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study)
The purpose of this study is to determine the clinically meaningful definition and prevalence of aspirin resistance based on data linking aspirin-dependent laboratory tests to recurrent vascular events in cardiovascular patients…
- Conditions
- Coronary Disease, Cerebral Infarction, Ischemic Attack, Transient
- Trial name
- NCT00250380
- Where
- 23 sites in Japan
- Volunteers
- 583 people
- Sponsor
- Ministry of Health, Labour and Welfare, Japan
Transient Ischemic Attack, Non-disabling Stroke
Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT
The objective of the Program of Rehabilitative Exercise and Education to avert Vascular Events after Non-disabling stroke and Transient ischemic attack (PREVENT) Trial is to determine whether the timely delivery of secondary…
- Trial name
- PREVENT (NCT00885456)
- Testing
- PREVENT program, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 187 people
- Sponsor
- Marilyn MacKay-Lyons
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital
Delirium, Ischemic Stroke
Post-stroke Delirium Screening
For a long time, delirium was considered a merely temporary dysfunction of the brain. Today, it is established that it is a brain disease associated with network dysfunction, neuroinflammation and impaired transmitter homeostasis…
- Conditions
- Delirium, Ischemic Stroke, Transient Ischemic Attack
- Trial name
- PSD Screen (NCT03930719)
- Testing
- Stroke screening tools
- Where
- Germany
- Volunteers
- 141 people
- Sponsor
- University Medicine Greifswald
Atrial Fibrillation, Transient Ischemic Attack
Optimal Detection of Atrial Fibrillation in TIA
Transient ischemic attack (TIA) is a common neurologic emergency. Although the detection of atrial fibrillation (AF) has identical consequences for preventive therapy in patients with ischemic stroke and TIA, the management…
- Trial name
- ODEA-TIA (NCT04075500)
- Testing
- Subcutaneously implanted event recorder (REVEAL LINQ), 28-day non-invasive continuous ECG monitoring (patch)
- Where
- 27 sites in Germany, Spain
- Volunteers
- 516 people
- Sponsor
- Alfried Krupp Krankenhaus
Stroke, Hypertension
DELPHI in Subjects at Risk for Stroke and Dementia
The DELPhi system is a software device that is used for the noninvasive evaluation of brain plasticity and connectivity. The DELPhi software uses EEG and TMS devices as accessories.
- Conditions
- Stroke, Hypertension, Diabete Mellitus, Dyslipidemias
- Trial name
- NCT03884647
- Testing
- DELPhI system
- Where
- 4 sites in United States, Israel
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Myocardial Infarction, Ischemic Stroke
Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease
Autoimmune diseases are diseases in which inappropriate immune responses that have the capability of harming host cells play an important role.
- Conditions
- Myocardial Infarction, Ischemic Stroke, Stroke, Subarachnoid Haemorrhage
- Trial name
- NCT02062021
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Ischemic Stroke, Transient Ischemic Attack
Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke
This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Carotid Artery Stenosis (Symptomatic and Asymptomatic)
- Trial name
- NCT07756775
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Stroke, Transient Ischemic Attack
International PFO Consortium
The prevalence of patent foramen ovale (PFO) is about 25% in the general population and approximately 40% in patients who have ischemic stroke of unknown cause (cryptogenic stroke).
- Trial name
- NCT00859885
- Testing
- Antithrombotic treatment, percutaneous device closure of PFO
- Where
- 18 sites in United States, Belgium and 4 more
- Volunteers
- 1,500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Peripheral Vascular Diseases
Screening DIVA - Diffuse Vascular Disease
Primary Objective: To investigate the value of the Edinburgh Claudication Questionnaire (ECQ) against the ankle-brachial index (ABI) in Canadian patients mainly followed in general practice, with documented acute coronary…
- Trial name
- NCT01076738
- Where
- Canada
- Volunteers
- 2,233 people
- Sponsor
- Sanofi
Ischemic Attack, Transient, Stroke
Colchicine for Prevention of Vascular Inflammation in Non-cardio Embolic Stroke
This study evaluates the use of Colchicine in adults over 40 years of age who have suffered an ischaemic stroke or transient ischaemic attack NOT caused by cardiac embolism or other defined causes.
- Trial name
- CONVINCE (NCT02898610)
- Testing
- Colchicine
- Where
- 145 sites in Belgium, Canada and 12 more
- Volunteers
- 3,154 people
- Sponsor
- University College Dublin
Acute Cerebral Ischemia
Field Randomization of Nerinetide (NA-1) Therapy in Early Responders
The purpose of this study is to determine whether nerinetide (NA-1) is effective in reducing global disability in patients with acute cerebral ischemia if administered early after symptom onset.
- Trial name
- FRONTIER (NCT02315443)
- Testing
- Nerinetide (NA-1)
- Where
- 4 sites in Canada
- Volunteers
- 532 people
- Sponsor
- NoNO Inc.
Transient Ischemic Attack, Minor Stroke
Multiple Interventions to Accelerate the Return to the Pre-event Level of Functioning After a TIA and Minor Stroke
The occurrence of a transient ischemic attack (TIA) or a minor stroke is frequently assumed as a temporary and non-disabling event.
- Trial name
- NCT05369637
- Testing
- Cognitive training, Physical exercise, Behavioral: Nutrition education
- Where
- Portugal
- Volunteers
- 70 people
- Sponsor
- Instituto de Saude Publica da Universidade do Porto