Clinical trials: Translational Research
Low Back Pain
Reliabılıty,Validity Of The Turkish Version Of The NIH-Minimal Dataset
This study, we performed the Turkish version validity and reliability of the NIH Task Force's Recommended Multidimensional Minimal Dataset
- Trial name
- NCT06049719
- Testing
- NIH Task Force's Recommended Multidimensional Minimal Dataset
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Gazi University
Use of Research Evidence
Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence
The investigators have developed an online database called 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is designed to support the use of research evidence by those working in the HIV/AIDS sector.
- Trial name
- NCT01257724
- Testing
- SHARE (Synthesized HIV/AIDS Research Evidence)
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ontario HIV Treatment Network
Eosinophilic Asthma, EGPA - Eosinophilic Granulomatosis With Polyangiitis
Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils
Introduction: The etiology and therapy of eosinophilic lung diseases are still poorly understood. For individual forms of disease, such as eosinophilic asthma or eosinophilic granulomatosis with polyangiitis (EGPA), new…
- Conditions
- Eosinophilic Asthma, EGPA - Eosinophilic Granulomatosis With Polyangiitis, Samter Triad, HES - Hypereosinophilic Syndrome
- Trial name
- PROMETHEos (NCT04538937)
- Testing
- no intervention
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
PK, PD, and Safety
A Study Evaluating the Bioavailability of Oral Insulin (N11005)
The objective of this study was to preliminarily verify whether the oral insulin N11005 is a prandial insulin by assessing the PK, PD, and safety profiles of N11005.
- Trial name
- NCT04975022
- Testing
- N11005, Novolin R
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Childhood Leukemia
Advanced Translational Research on Childhood Leukemia
Prognosis of children with leukemia, the most common pediatric cancer, has improved markedly. Yet, relapse still occurs in 15-40% of patients with a probability of survival of <50%, which is unlikely to be boosted by…
- Trial name
- NCT04478006
- Testing
- RNA-seq, whole exon sequencing, Cytogenetics test
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Electrochemically Sensing Prob, Breast Cancer Diagnosis
Electrochemical Biosensor Based on Lectin-functionalized Nitrogen, Sulfur-doped Graphene Quantum Dot Decorated Gold Nanoparticles for Breast Cancer Diagnosis: From Academic Research to Clinical Translation
In this research, considering benefits of the nitrogen, sulfur-doped graphene quantum dot (NSGQDs) and 3-dimensional gold nanoparticle (AuNP), we used these materials for the construction of a novel electrochemical biosensor to…
- Trial name
- NCT07034248
- Testing
- Electrochemical biosensor
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Tuberculosis
Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to Treatment
Tuberculosis bacterium (TB) is a germ that can infect any part of the human body, especially the lungs. Vitamin D is a hormone present in humans that regulates blood electrolytes such as calcium and phosphate.
- Trial name
- NCT00918086
- Testing
- Vitamin D pill
- Where
- Georgia
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Emory University
Healthy
Investigating ELSI Issues That May Facilitate or Impede Clinical Translation of Epigenetic Research. Phase 3a Survey
Few people realize that environmental pollution and some behaviors like physical activity and tobacco smoking can affect their health by "turning on" or "turning off" certain genes through a process called "epigenetic…
- Trial name
- NCT07713667
- Testing
- Uncertainty Video, Uncertainty Normalization Video, Epigenetics Video
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Preventive Services, Immunizations
Delivery of Preventive Services in Primary Care
The major goal of this project is to determine the effectiveness of a multi-component intervention designed to help primary care practices implement three office system strategies known to increase delivery of immunizations and…
- Conditions
- Preventive Services, Immunizations, Screening
- Trial name
- NCT00115557
- Testing
- Practice intervention, Practice intervention 2
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetes Mellitus, Cardiovascular Disease
SPREAD-NET: PRactices Enabling Adapting and Disseminating in the Safety NET
The investigators propose to compare the effectiveness of 3 strategies (low, medium, high intensity) at supporting CHCs' implementation of the ALL Initiative (an intervention shown to reduce patients' cardiovascular disease (CVD)…
- Trial name
- SPREAD-NET (NCT02325531)
- Testing
- Low support, Medium support, High support
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Heart Failure
Asian neTwork for Translational Research and Cardiovascular Trials ("ATTRaCT")
To build on Singapore's competitive advantages in advanced cardiac imaging, genetic and molecular studies to develop an integrated "one -stop" platform spanning from human to large and small animal models, dedicated to deepening…
- Trial name
- NCT02791009
- Testing
- Cardiovascular Magnetic Resonance Imaging (CMRI), Electrocardiogram (ECG), Blood Sample Collection
- Where
- Singapore
- Volunteers
- 815 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Posttraumatic Stress Disorder
Resilient Roots: Supporting Youth and Families
Resilient Roots is integrated into the TRANSFORM Center to promote translation of research findings into clinical interventions, to inform the next generation of research on child abuse and neglect (CAN), and to facilitate…
- Trial name
- NCT06535516
- Testing
- Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) augmented with Socialization (S)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Mandibular Hypoplasia
Applicability Clinic of Cement Portland Structural White in Endodontic Surgery
Thirty teeth twelve patients, two female and a male, who had persistent periradicular lesions were selected to participate in this study.
- Trial name
- NCT02474615
- Testing
- ENDODONTIC SURGERY
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
School-based Intervention, Sleep
Educational Intervention for Sleep Hygiene Nursing in Adolescents
There is an urgent need to influence the knowledge and beliefs associated with sleep (TV viewing, use of electronic devices, sedentary activity...) of school children through holistic interventions involving students, parents…
- Trial name
- ENISHA-ST (NCT06805708)
- Testing
- Sleep hygiene training programme
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Behavior and Behavior Mechanisms
Translational Research to Inform Interventions for Challenging Behavior
This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts.
- Trial name
- NCT04842500
- Testing
- Demand Informed Moderator Analysis
- Where
- 5 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Bulimia Nervosa, Eating Disorders
Motivating Factors That Play a Role in Bulimia Nervosa
This study will evaluate whether people with bulimia nervosa will binge eat in a structured laboratory setting and display behavioral patterns similar to those of individuals who are dependent on drugs.
- Trial name
- NCT00304174
- Testing
- Motivation to eat
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Healthy, Adult
Understanding Effects of Calcium on the Gut-Bone Axis
The study team is inviting 13 healthy people to complete a study to explore how calcium affects hormones and bones after eating. Participants will be asked to complete two study visits within eight weeks.
- Conditions
- Healthy, Adult, Calcium, Bone Resorption
- Trial name
- NCT06383117
- Testing
- Calcium carbonate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Genetic Disease, Nervous System Diseases
Prospective Cohort Study of Neurogenetic Diseases
Neurogenetic diseases (NGD) represent rare and hereditary forms of neurological diseases. The goal of CNGD is to create a one-window approach for NGDs, to facilitate and accelerate participation in research projects through deep…
- Trial name
- CNGD (NCT06048523)
- Testing
- Patient cohort, Control cohort
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Aggression, Conduct Disorder
Real-time fMRI for the Treatment of Aggressive Behavior in Adolescents
The purpose of this study is to determine whether real-time fMRI feedback is effective in the treatment of aggressive behavior problems in adolescents with high callous unemotional traits when compared to treatment as usual.
- Trial name
- NCT02563145
- Testing
- Real-time fMRI feedback, Treatment as usual
- Where
- Germany
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim