Clinical trials: Transplantation, Liver
Education
Video-supported Training in Line With the Health Belief Model
Summary The only treatment method for those with incurable, irreversible, progressive, acute or chronic liver disease is liver transplantation.
- Trial name
- NCT06138379
- Testing
- Experimental: 1st Experimental Group, Experimental: 2nd Experimental Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Solid Organ Transplant, Heart Transplant
REmote moBile Outpatient mOnitoring in Transplant 2.0
This study is designed to determine if an innovative mobile health intervention designed to improve patient-provider communication can reduce unscheduled hospitalizations, and visits to the emergency department and ambulatory…
- Conditions
- Solid Organ Transplant, Heart Transplant, Liver Transplant, Kidney Transplant
- Trial name
- Reboot (NCT04721288)
- Testing
- Active communication through Reboot application, Generic communication through Reboot application
- Volunteers
- 400 people
- Sponsor
- University Health Network, Toronto
Liver Transplantation, Fatigue
Home-Based Exercise Education in Liver Transplant Recipients
Liver transplant recipients often experience reduced physical activity levels, fatigue, and increased caregiver burden after transplantation. Structured home-based exercise education may help improve these outcomes.
- Conditions
- Liver Transplantation, Fatigue, Physical Inactivity
- Trial name
- Liv (Liver) (NCT07417423)
- Testing
- Home-Based Exercise Education, Brochure-Based Exercise Education (Experimental)
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Hasan Kalyoncu University
Evidence of Liver Transplantation
The Study to Evaluate Efficacy and Safety of MY-REPT Capsule in Primary, Liver Transplantation Recipients (MYLT1)
Efficacy and safety of MY-REPT capsule in primary, liver transplantation recipients
- Trial name
- NCT01766518
- Testing
- Mycophenolate mofetil
- Where
- 3 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Immunodeficiency Secondary to Organ Transplantation
Evolution of Interleukin 7, Fat Mass and Metabolic Profile Before and After Transplantation
Three different white adipose tissue-related disorders, whether due to its excess (obesity), absence (lipoatrophies) or aberrant distribution (lipodystrophies), are paradoxically able to induce metabolic insulin resistance…
- Trial name
- IL-7tran (NCT01414660)
- Testing
- transplantation
- Where
- 5 sites in France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Lille
Frailty, Cirrhosis
LIFT Intervention in Liver Transplant Candidates
Frailty is a significant problem in patients undergoing liver transplant and is associated with poor outcomes and survival. Hence, optimizing physical fitness and counteracting frailty is important.
- Conditions
- Frailty, Cirrhosis, Liver Transplant
- Trial name
- NCT04836923
- Testing
- "LIver FrailTy" intervention (LIFT)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Northwestern University
Liver Allograft
Second-Generation Laryngeal Mask Airway vs Endotracheal Intubation in Adult Liver Transplantation
This prospective, multicenter, randomized controlled trial aims to evaluate the safety and feasibility of second-generation laryngeal mask airway (LMA) management compared with conventional endotracheal intubation (ETT) during…
- Trial name
- NCT07775521
- Testing
- Second-Generation Laryngeal Mask Airway, Endotracheal Intubation Airway Management
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou Medical University
Liver Transplantation, Postoperative Recovery
Effects of The Telerehabilitation-Based Exercise Program in Liver Transplant Patients
This randomized controlled study aims to evaluate the effects of a telerehabilitation-based exercise program on muscle strength, exercise capacity, fatigue level, and cognitive status in adult liver transplant recipients.
- Conditions
- Liver Transplantation, Postoperative Recovery, Muscle Weakness, Functional Capacity
- Trial name
- NCT07425314
- Testing
- Telerehabilitation Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Hasan Kalyoncu University
Alcoholic Hepatitis
Fecal Microbial Transplantation in Severe Alcoholic Hepatitis
1. A subtype of Alcoholic hepatitis (AH), named severe alcoholic hepatitis (SAH) is associated with high short-term mortality (J Hepatol, 2019) 2.
- Trial name
- FMTH7 (NCT04758806)
- Testing
- Fecal microbial transplantation
- Where
- Slovakia
- Volunteers
- 50 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Haemopoietic Stem Cell Transplantation, Allograft
Impact of a Fourth Hexavalent Vaccine After Hematopoietic Stem Cell Transplantation
It is recommended for patients who underwent an hematopoietic stem cell transplantation to receive 6 months after the graft 3 injections of hexavalent vaccine (diphteria-tetanus- poliomyelitis-pertussis-Hib-HBV) within 2 months…
- Trial name
- EVaxAll (NCT03402776)
- Testing
- 4th dose of hexavalent vaccine 1 month after the 3rd dose
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Liver Transplant; Complications, COVID19
COVID-19 in Liver Transplant Recipients
Prospective observational study aimed at analyzing the incidence, clinical characteristics and outcomes of COVID-19 in LT in Spain.
- Conditions
- Liver Transplant; Complications, COVID19, Respiratory Failure
- Trial name
- COVID19-SETH (NCT04361591)
- Testing
- Observational only
- Where
- Spain
- Volunteers
- 121 people
- Sponsor
- Hospital Clinic of Barcelona
Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately
Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation
Tacrolimus is the most commonly used immunosuppressant for preventing and treating rejection after liver transplantation. However, its treatment window is narrow, the pharmacokinetic individual differences are large, routine dose…
- Conditions
- Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately, Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients, According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the Cases and Grading of Postoperative Acute Kidney Injury in 60 Patients Were Counted
- Trial name
- NCT06319391
- Testing
- CYP3A5*1*、CYP3A5*1*3, CYP3A5*3*3
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziqiang Li
Impaired Oxygen Delivery, Transplant; Failure, Liver
Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Patients Undergoing Liver Transplantation Surgery
Mixed venous oxygen saturation (SvO2) is an important parameter in the management of patient during liver transplantation surgery especially during portal vein clamping.
- Trial name
- NCT04778150
- Testing
- VO 100 medical device from Mespere LifeSciences
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Geneva
Liver Transplant, Hepatitis C
The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients
This is an open-label, pilot trial to test the safety and efficacy of transplantation of livers from Hepatitis C seropositive non-viremic (HCV Ab+/NAT-) and HCV seropositive viremic (HCV Ab+/NAT+) donors to HCV seronegative…
- Trial name
- NCT03819322
- Testing
- sofosbuvir/velpatasvir
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Fernanda P Silveira, MD, MS
Blood Loss, Postoperative, Liver Transplant
Individualized Multimodal Hemostasis Evaluation Pyramid (IMHOTEP)
This study evaluates the hemostatic changes defined as hemostasis reserve capacity (HRC) in the first perioperative 48 hours of bloodless liver transplanted patients.
- Conditions
- Blood Loss, Postoperative, Liver Transplant, Hemostatic Disorder
- Trial name
- NCT03555383
- Testing
- Coagulation factor levels
- Where
- Hungary
- Volunteers
- 59 people
- Sponsor
- Semmelweis University
Hepatitis E
Prevalence of Hepatitis E During Follow-up Liver and Kidney Transplant Patients in Guadeloupe, French West Indies
Hepatitis E is well known to be a common cause of severe hepatitis on organ-transplanted people. However, several studies also show a risk of transition to a chronic state.
- Trial name
- KARU-HEP (NCT07729202)
- Testing
- Liver and Kidney transplanted patients
- Where
- Guadeloupe
- Volunteers
- 95 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Rheumatoid Arthritis, Psoriatic Arthritis
Vaccine Response to COVID-19 Vaccines in Patients Using Immunosuppressive Medication
The purpose of this study is to assess the strength and duration of the immunological response to COVID-19 vaccines in patients treated with immunosuppressive and/or immunomodulating medication for immune-mediated inflammatory…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Spondyloarthritis, Crohn Disease
- Trial name
- Nor-vaC (NCT04798625)
- Where
- 2 sites in Norway
- Volunteers
- 2,300 people
- Sponsor
- Diakonhjemmet Hospital
Drug-drug Interaction, Liver Transplantation
Pharmaco-proteomic Platform to Evaluate Drug Interactions in Liver Transplant Patients
The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of…
- Trial name
- NCT06682325
- Testing
- Multi-drug interaction
- Where
- 3 sites in Chile
- Volunteers
- 48 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Liver Transplant Failure and Rejection, Children, Only
Histologic Evolution of Patients With Liver Transplantation
Certain pediatric liver transplant patients with immunosuppression levels in the therapeutic range and normal liver function tests present histological alterations (inflammation or fibrosis) in protocol biopsies.
- Trial name
- NCT06103097
- Testing
- No interventions done (obervational)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Vall d'Hebron
Liver Transplantation
Prospective Evaluation of Predictors for Organ Failure Following Liver Transplantation
Early organ failure occurs frequently and is difficult to predict. The study aims to define a predictive score for early transplant failure.
- Trial name
- NCT00408889
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Heidelberg University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.