Clinical trials: Transplantation, Liver
Liver Transplant Recipients
L-arginine for Prevention of Kidney Damage in Liver Transplant Recipients
Chronic renal insufficiency is a common and important health problem that causes morbidity and mortality among patients who have undergone liver transplantation.
- Trial name
- NCT00587418
- Testing
- L-arginine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Heart Transplantation, Liver Transplantation
Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement
The aims of this 3-year randomized, single-blinded clinical trial are to compare the effect of high and low feedback about performance on the bedside exercise device in heart or liver transplantation recipients during the…
- Trial name
- NCT01705015
- Testing
- direct feedback about exercise
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- National Taiwan University Hospital
Progressive Familial Intrahepatic Cholestasis
Prospective Analysis of the Treatment of Progressive Familial Intrahepatic Cholestasis (TreatFIC)
The project has the following general aims: 1. Natural course and prognosis: To prospectively follow the natural course and prognosis of the different types of PFIC, to broaden the understanding of the different very rare…
- Trial name
- TreatFIC (NCT06778174)
- Testing
- observational study
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- University Medical Center Groningen
Liver Cancer
Contrast-Enhanced CT and MRI in Diagnosing and Staging Liver Cancer Using UNOS Policy
RATIONALE: Diagnostic procedures, such as contrast-enhanced CT scan and contrast-enhanced MRI, may help find liver cancer and find out how far the disease has spread.
- Trial name
- ACRIN6690 (NCT01082224)
- Testing
- iodinated contrast dye, motexafin gadolinium, Eovist-enhanced MRI
- Where
- 9 sites in United States
- Volunteers
- 440 people
- Sponsor
- American College of Radiology Imaging Network
Liver Transplantation
Effect of Rapid Transfusion With Fluid Management System 2000® (FMS)
Rapid infusion of red blood cells is known to result in the increase of plasma potassium. The researchers are trying to investigate the change in plasma potassium during rapid infusion of mixed blood components in the reservoir…
- Trial name
- FMS (NCT01448343)
- Testing
- Fluid management system 2000 (FMS)
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Hepatocellular Injury
Interest of Oxygenated Hypothermic Perfusion (PHO) in Preservation of Hepatic Grafts From Expanded Criteria Donors
Interest of oxygenated hypothermic perfusion in preservation of hepatic grafts from expanded criteria donors.
- Trial name
- PERPHO (NCT03376074)
- Testing
- Hypothermic oxygenated perfusion (HOPE), Conventional cold storage
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Rennes University Hospital
Post-transplant Hepatitis C
Expanded Access Program of Sofosbuvir With Ribavirin and With or Without Pegylated Interferon in Aggressive Post-transplant Hepatitis C
This is a single arm, open-label study which will be opened at specific clinical sites at the request of an investigator for the treatment of individual subjects for whom there are no other treatment options.
- Trial name
- NCT01779518
- Testing
- Sofosbuvir, Ribavirin, Pegylated Interferon
- Sponsor
- Gilead Sciences
Progressive Familial Intrahepatic Cholestasis
NAtural Course and Prognosis of PFIC and Effect of Biliary Diversion
The natural course of PFIC syndromes and the effect of diversion techniques, have so far not been characterized in a rigorous manner within a larger population of patients.
- Trial name
- NAPPED (NCT03930810)
- Testing
- Surgical biliary diversion
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- University Medical Center Groningen
Liver Transplantation, Mycoses
Liver Transplant European Study Into the Prevention of Fungal Infection
Prevention of invasive fungal infection in high risk patients following liver transplant.
- Trial name
- TENPIN (NCT01058174)
- Testing
- micafungin, fluconazole, liposomal amphotericin B
- Where
- 36 sites in Austria, Belgium and 12 more
- Volunteers
- 350 people
- Sponsor
- Astellas Pharma Inc
Colorectal Cancer, Liver Metastasis
Liver Transplantation for Colorectal Cancer
This is an observational study that will follow adults with stage IV colorectal cancer whose disease has spread only to the liver (not to other organs) and who are undergoing a liver transplant as part of their cancer treatment.
- Trial name
- NCT07884110
- Testing
- Liver transplantation
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Exocrine Pancreatic Insuficiency
Determine the Prevalence of Exocrine Pancreatic Insufficiency (EPI) in Pediatric and Adult Participants With Alagille Syndrome After Liver Transplantation
The goal of this clinical trial is to determine the prevalence of exocrine pancreatic insufficiency (EPI) in a population of pediatric and adult participants with Alagille Syndrome (ALGS) post liver transplant.
- Trial name
- NCT07335523
- Testing
- Fecal Fat
- Where
- 9 sites in United States
- Volunteers
- 30 people
- Sponsor
- Digestive Care, Inc.
Hepatocellular Carcinoma
Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)
The purpose of this study is to evaluate the anti-tumor effect of sirolimus-based immunosuppressive regimen in patients following living donor liver transplantation for hepatocellular carcinoma exceeding Milan criteria with…
- Trial name
- Sirolimus (NCT01374750)
- Testing
- Sirolimus, m-TOR inhibitor free
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Seoul National University Hospital
Liver Fibrosis After Liver Transplantation, Multiparameter Magnetic Resonance Imaging
Mp-MRI in the Diagnosis of Liver Fibrosis After Liver Transplantation
It is an open label observation clinical trial, all participants are liver transplant patients. The investigators deem to make a better criteria for assessing liver fibrosis after liver transplantation.
- Trial name
- NCT05292885
- Testing
- Gadopentetate Dimeglumine Injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Liver Transplant
Controlled Donors After Circulatory Death and Brain Death: a Multicenter Study of Transfusion, One-year Graft Survival and Mortality. Cohort Study,
RBC requirement ein DBD and DCD liver transplants
- Trial name
- NCT04945135
- Where
- 2 sites in Spain
- Volunteers
- 591 people
- Sponsor
- Hospital Clinic of Barcelona
Liver Disease
Minocycline Administration During Human Liver Transplantation
Liver transplantation is the sole therapy for end-stage liver diseases and acute liver failure in children and adults. However, use of this life-saving technique is limited due to a severe shortage of donor livers.
- Trial name
- NCT02712775
- Testing
- Minocycline (yes/no)
- Where
- United States
- Sponsor
- Medical University of South Carolina
Obesity, Liver Transplantation
Immunosuppression and Diet: the Role of Inflammation in the Adipose Tissue Remodeling
The main goal of this project is to evaluate the effect of immunosuppression in the weight loss and in the metabolic status of patients after liver transplantation.
- Trial name
- NCT03103984
- Testing
- Weight loss diet
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Liver Transplant, Carbapenem-resistant Enterobacterales
Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase Producing Enterobacterales Undergoing Liver Transplantation
This is a multicenter stepped-wedge cluster randomized trial, conducted over a 2-year period at three hospitals. The trial is structured into four phases, each lasting six months.
- Conditions
- Liver Transplant, Carbapenem-resistant Enterobacterales, CRE Colonization
- Trial name
- TAILOR (NCT07759453)
- Testing
- Ceftazidime - Avibactam ( CAZ-AVI), Meropenem-Vaborbactam, Imipenem+Relebactam
- Where
- 3 sites in Italy
- Volunteers
- 168 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
HIV Infection, AIDS
HIV Liver Regeneration Project for HIV Patients With Cirrhosis by Autologous Bone Marrow Transplantation
An international investigation to evaluate if, and if so how long, autologous bone marrow hematopoietic stem cell transplantation can safely restore liver functions for HIV infected patients who have decompensated liver cirrhosis.
- Conditions
- HIV Infection, AIDS, Cirrhosis
- Trial name
- HIV-ABMi (NCT01309594)
- Testing
- Hematopoietic stem cell transplantation
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- National Center for Global Health and Medicine, Japan
Liver Transplant Disorder
Perioperative Analgesia by ESP Catheter on Recipient for Liver Transplantation
Enhanced recovery after surgery (ERAS) programs were developed by Prof Henrik Kehlet in Denmark to reduce the hospitalization and improve the surgical outcomes.
- Trial name
- ESPLIVERRec (NCT04584151)
- Testing
- regional analgesia
- Where
- 2 sites in Vietnam
- Volunteers
- 11 people
- Sponsor
- Vinmec Healthcare System
Liver Transplant; Complications
Immune Function Following Liver Transplantation
Post-operative care following liver transplantation is characterized by a high incidence of infective and immunological complications.
- Trial name
- SEPTIFOIE (NCT04302246)
- Testing
- Biological testing on sequential blood sample
- Volunteers
- 61 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.