Clinical trials: Transplantation: Facial Transplantation
Osteitis, Limb Salvage
Allogeneic Vascularized Knee Transplantation
High energy trauma often results in severe soft tissue, bone and joint injury. Today, many methods and techniques exist to treat theses severely injured extremities.
- Conditions
- Osteitis, Limb Salvage, Joint Deformities, Acquired, Skin Transplantation
- Trial name
- kneeTx (NCT01133145)
- Testing
- knee joint transplantation
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- University of Jena
Nasolabial Folds, Glabellar Crease
Autologous Fibroblast Transplantation in Facial Deformities
Beautiful skin requires maintenance of proper care. Skin exercise, protections from direct sunlight or harsh wind, and maintaining a healthy diet are some of the ways of having a good and radiant skin.
- Conditions
- Nasolabial Folds, Glabellar Crease, Deep Wrinkles of the Forehead, Acne Scars
- Trial name
- NCT01115634
- Testing
- Fibroblast, fibroblast and gel
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Breast Hypoplasia and Facial Ageing
Cosmetic Fat Transplantation Using Expanded ASC Enriched Fat Grafts
The purpose of the present study is to examine whether enrichment of a fat graft with autologous ex vivo expanded ASC injected into the breast tissue or face, both for cosmetic use, will significantly improve the results of…
- Trial name
- NCT03258164
- Testing
- ASC enriched lipofilling, Standard Lipofilling
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stemform
Facial Vascularized Composite Allotransplantation, Functional Recovery
Facial Vascularized Composite Allotransplantation: A Study Evaluating Safety, Functional Outcomes, and Patient-Reported Psychosocial Outcomes
The primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of facial vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
- Trial name
- NCT07810764
- Testing
- Facial Vascularized Composite Allotransplantation (VCA)
- Where
- 9 sites in United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Eye Injury
Transplantation of Cultivated Corneal Epithelial Sheet in Patients With Ocular Surface Disease
The aim of the study is to assess if transplantation of cultivated corneal epithelial stem cells could restore vision in patients with severe ocular surface disorder with a favourable safety profile that warrants further…
- Trial name
- CLET (NCT01123044)
- Testing
- conservative, Medical Therapy
- Where
- Malaysia
- Volunteers
- 42 people
- Sponsor
- Ministry of Health, Malaysia
Skin Transplantation, Reconstructive Surgical Procedures
Effect of Platelet-Rich Plasma on Graft Uptake and Postoperative Outcomes in Full-Thickness Skin Grafting of Face and Neck
This clinical study aims to evaluate whether applying platelet-rich plasma (PRP), a substance made from a person's own blood, can improve the success of full-thickness skin grafts used to treat facial and neck wounds.
- Trial name
- NCT07112898
- Testing
- Platelet-Rich Plasma (PRP), Standard Skin Grafting
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Severe Facial Deformity
Face Transplantation for Treatment of Severe Facial Deformity
Face transplantation surgery is the transfer of face tissue from a deceased human donor to a patient with a severe facial deformity.
- Trial name
- NCT01281267
- Testing
- Facial Allograft Transplantation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Severe Facial Deformities
Face Transplantation Clinical Trial
The purpose of this study is to apply human facial allograft transplant to the subjects with severe facial deformities or disfigurements in order to provide adequate coverage, aesthetic appearance and functional outcome.
- Trial name
- NCT01269164
- Testing
- Surgical Procedure Composite Facial Transplant
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Facial Trauma, Facial Deformity
Face Transplantation
Face allotransplantation will be performed in facial trauma patients. Immune suppression will primarily be provided according to standard three-drug regimen.
- Conditions
- Facial Trauma, Facial Deformity, Facial Injuries
- Trial name
- NCT05699187
- Testing
- Face allotransplantation
- Sponsor
- Massachusetts General Hospital
Facial Injuries, Traumatic Wounds and Injuries
Human Craniomaxillofacial Allotransplantation
Background: The human face is critically important for breathing, eating, seeing, and speaking/ communicating, but its most important job may be to look like a human face.
- Conditions
- Facial Injuries, Traumatic Wounds and Injuries, Craniofacial Injuries, Craniofacial Defects
- Trial name
- NCT01889381
- Testing
- Bone marrow cell-based therapy & 1-drug immunosuppression.
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Pharmaceutical Preparations
Human Partial Facial Allotransplantation
Progress in composite tissue allotransplantation provides a new remedy for severely disfigured patients. We plan to carry out allograft composite tissue transplantation after a careful systemic preparation.
- Trial name
- NCT00663988
- Testing
- human transplantation
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Xijing Hospital
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Eye Burns
The Role of Amniotic Membrane Transplantation in Ocular Chemical Burns
This is a randomized clinical trial study to identify the role of AMT (amniotic membrane transplantation) in treating epithelial defect, symblepharon prevention preventing corneal vascularization and opacity decreasing pain and…
- Trial name
- NCT00370812
- Testing
- amniotic membrane transplantation
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Corneal Injuries, Corneal Burns
Stem Cells Therapy for Corneal Blindness
This is a investigative initiated, comparative pilot clinical trial to ascertain the safety of application of ex-vivo cultivated limbal stem cells in human eyes for treating different superficial corneal pathologies.
- Conditions
- Corneal Injuries, Corneal Burns, Corneal Scars and Opacities
- Trial name
- ExCell (NCT02948023)
- Testing
- Ex-vivo cultivated limbal stem cell pool
- Where
- India
- Volunteers
- 100 people
- Sponsor
- L.V. Prasad Eye Institute
Disfigurement of Face
Self-Face Recognition After Face Transplantation
The purpose of the proposed study is to use functional magnetic resonance imaging (fMRI) to investigate how a change in facial appearance is initially represented in brain circuits and then alters over time, as the new face…
- Trial name
- NCT03027141
- Testing
- Face recognition task
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Facial Injuries
Craniomaxillofacial Allotransplantation
The purpose of this study is to perform face transplants on people who have suffered severe facial trauma with tissue and functional loss; and evaluate the acceptance and function of the transplanted tissue.
- Trial name
- NCT02158793
- Testing
- Craniomaxillofacial allotransplantation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Corneal Scars and Opacities
To Evaluate the Clinical Safety and Efficacy of Limbal Stem Cell for Treatment of Superficial Corneal Pathologies".
This study proposes to investigate the transplantation of ex-vivo cultivated allogenic limbal stromal cells for the treatment of the corneal pathologies.
- Trial name
- NCT04932629
- Testing
- Ex-vivo cultivated Allogeneic limbal stromal stem cells
- Volunteers
- 20 people
- Sponsor
- L.V. Prasad Eye Institute
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Transplantation: Facial Transplantation
Face Transplantation
This study aims to: 1. Perform face transplants on people who have suffered severe facial trauma with tissue and functional loss; and 2. Evaluate the acceptance and function of the transplanted tissue.
- Trial name
- NCT01140087
- Testing
- Face Transplant
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Maryland, Baltimore
Face Injuries, Hand Injuries
Craniomaxillofacial and Upper Extremity Allotransplantation
The purpose of this study is to evaluate functional and aesthetic outcomes of combined facial and upper extremity composite tissue allografts on patients who have not achieved functional and aesthetic outcomes with conventional…
- Conditions
- Face Injuries, Hand Injuries, Craniofacial Injuries, Upper Extremity Injuries
- Trial name
- NCT04057638
- Testing
- Combined Craniomaxillofacial and Upper Extremity Allotransplantation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health