Clinical trials: Trauma, Spinal Cord
Spinal Cord Injury, Urinary Incontinence
Two Devices for Reflex Voiding Following Spinal Cord Injury
The purpose of this investigation is to evaluate methods in spinal cord injured individuals to improve reflex urination. Anal dilation will be investigated to reduce high urethral resistance and a vibrator on the patient's bottom…
- Trial name
- NCT00662207
- Testing
- Vibrator, Anal dilator
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries
Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury
The purpose of this research is to learn about how the participant's body is able to balance changes in blood pressure, and how spinal cord stimulation affects these changes as well as immune \& cardiovascular function in…
- Trial name
- NCT07210411
- Testing
- Tests of sympathetic inhibition, Tests of above level sympathetic activation, Testing of below level sympathetic activation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain, Inflammatory Response
Association Between Body Composition and Pain in Spinal Cord Injury
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and…
- Trial name
- NCT05459207
- Testing
- Moderate Fat Meal, High Fat Meal
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Autonomic Dysreflexia, Spinal Cord Injuries
Prevention of Complications Due to Autonomic Dysreflexia in SCI Individuals
Autonomic dysreflexia (AD) is a syndrome of unbalanced response of the sympathetic system to noxious stimuli below the level of spinal cord injury (SCI), characterized by paroxysmal hypertension.
- Trial name
- NCT05024487
- Testing
- Clinical Examination
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Assoc. Prof. Jiri Kriz, MD, PhD
Spinal Cord Injury
Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07418398
- Testing
- Exoskeleton-Assisted Walking (EAW), Active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury
Early detection of response to therapeutic intervention is vital, as it will enable early termination of intervention in non-responding patients, prevent unnecessary financial burden, and allow for early changes to the…
- Trial name
- NCT03854214
- Testing
- Functional Electric Stimulation cycling, Passive cycling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Spinal Cord Injury
Cardiovascular Autonomic Function After Resistance Training
The purpose of this clinical trial is to evaluate whether an 8-week upper-limb resistance training program improves cardiovascular autonomic function in adults with chronic spinal cord injury (SCI).
- Trial name
- NCT07725952
- Testing
- Upper-Limb Resistance Training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital
Spinal Cord Injury
Functional Electrical Stimulation (FES) Cycling for Children With Spinal Cord Injuries (SCI)
The overall objective of this research project is to examine the clinical efficacy of lower extremity cycling with functional electrical stimulation to improve the health and fitness of children with spinal cord injuries (SCI).
- Trial name
- NCT00245726
- Testing
- FES Cycle, ES therapy, Passive (Motor Assist) Cycle
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Shriners Hospitals for Children
Spinal Cord Injury, Chronic Neuropathic Pain
VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY
The goal of this feasibility study is to assess the feasibility of the combined treatment intervention "virtual walking (VW) and transcranial direct current stimulation (tDCS)" of neuropathic pain in patients with spinal cord…
- Trial name
- NCT06710808
- Testing
- Virtual walking and transcranial direct current stimulation
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spinal Cord Injury, Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI (WINY)
This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT07222033
- Testing
- Hands-free exoskeleton
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Spinal Cord Injuries (SCI), Depression
Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults With SCI
The investigators propose a pilot randomized clinical trial to determine if adults with spinal cord injury (SCI) show improved cognitive function and depression following home-based Action Observation and Motor Imagery (AOMI)…
- Conditions
- Spinal Cord Injuries (SCI), Depression, Motor Imagery, Cognitive Functions
- Trial name
- NCT06708026
- Testing
- Action Observation and Motor Imagery (AOMI) training, Basic wheelchair exercises, Watch landscape videos
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Shoulder Impingement
Effects of PNF on Shoulder Pain in Paraplegic Manual Wheel Chair Users
This project was a Randomized control trial conducted to check the Effects of Proprioceptive Neuromuscular Facilitation on Shoulder Pain due to chronic impingement syndrome in paraplegic Manual Wheelchair users after Spinal Cord…
- Trial name
- NCT04967911
- Testing
- Rhythmic stabilization exercises, conventional treatment
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Tetraplegia, Asthma
Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury
The purpose of this study is to obtain markers of airway inflammation from the exhaled breath condensate (the moisture in exhaled air) for comparison to blood based markers.
- Trial name
- NCT02235714
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries (SCI), Spinal Cord Injury
Study on Preliminary Safety and Efficacy of Epidural Electrical Stimulation to Manage Lower Urinary Tract Dysfunction After Spinal Cord Injury
This clinical trial aims to assess the preliminary safety and efficacy of Epidural Electrical Stimulation (EES) therapy in managing lower urinary tract dysfunction in individuals with sub-acute or chronic spinal cord injury…
- Trial name
- ReeVoid (NCT06845904)
- Testing
- WaveWriter Alpha™ neurostimulation system
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Spinal Cord Injury
Virtual Sport for Adults ≥ 50 Years With Spinal Cord Injury
Sport is a physical activity that has many physical, psychological and social benefits for those with spinal cord injury (SCI). However, most sport research involves people with SCI who are <50 years old.
- Trial name
- NCT06040749
- Testing
- Virtual group-based handcycling
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injuries, Psychological Distress
A Guided Online ACT Intervention Combined With Psychoeducation for People With Spinal Cord Injury
The purpose of this preliminary study is to examine the effects of a guided online acceptance and commitment therapy (ACT) intervention combined with psychoeducation on people with spinal cord injury (SCI) who experience…
- Trial name
- NCT04670406
- Testing
- acceptance and commitment therapy (ACT) combined with psychoeducation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Xerosis
Safety and Efficacy of SQIN™ on Xerosis in Adults With Mobility Problems and Paralysis
In the general population, xerosis is often caused by external factors such as seasonal changes. In that case, the best way to relieve dry skin is to use a standard moisturizer.
- Trial name
- NCT02429206
- Testing
- SQIN, standard moisturizing cream (Glaxal Base)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Nordic Life Science Pipeline Inc.
Perinatal Spinal Cord Injury
Understanding Perinatal Spinal Cord Injury
The purpose of this study is to deepen our understanding of children who have a cervical spinal cord injury obtained in utero or at birth and examine the effects of tailored activity-based recovery training (ABRT) in combination…
- Trial name
- NCT06808035
- Testing
- Activity-Based Recovery Training, Transcutaneous Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Spinal Cord Injury
The ATLET Study: Can Subjects With Incomplete Spinal Cord Injury Learn to Walk?
The ATLET study will assess the effect of manual or robotic body-weight supported locomotor training of patients with stable motor incomplete spinal cord injury (SCI) on gait and overall ADL function as well as on estimated…
- Trial name
- ATLET (NCT00854555)
- Testing
- Locomotor training with robot, Locomotor training with manual assistance
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- North Norway Rehabilitation Center
Spinal Cord Injury, Peer Group
A Patient-centered Approach to Successful Community Transition After Catastrophic Injury
Shepherd Center is bringing a more patient-centered focus to educational, peer-support, and technology resources offered to patients with spinal cord injury and their families and is evaluating these changes.
- Trial name
- NCT02746978
- Testing
- Peer directed education, Patient Engagement Portal
- Volunteers
- 800 people
- Sponsor
- Shepherd Center, Atlanta GA
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